Midodrine for Sepsis Treatment and Early Vasopressor Weaning (MID-STEP): protocol for a pragmatic randomised clinical trial [0.03%]
Aysun Tekin,Gabriele Halpern,Diksha Gowda et al.
Aysun Tekin et al.
Introduction: Sepsis is a global health priority with nearly 50 million cases annually. Cardiovascular dysfunction is common, frequently manifesting as hypotension that persists despite fluid resuscitation. Most affected ...
Rehabilitation intervention to improve Recovery after an Episode of Delirium in adults over 65 years (RecoverED): a multicentre, single-arm feasibility study in NHS acute hospitals in the UK [0.03%]
Louise Allan,Jinpil Um,Abby O&#x;Connell et al.
Louise Allan et al.
Objectives: To test a theory-informed, person-centred rehabilitation intervention for older adults following a hospital admission complicated by delirium, developed in line with the Medical Research Council framework for ...
Multicenter Study
BMJ open. 2026 Apr 22;16(4):e102316. DOI:10.1136/bmjopen-2025-102316 2026
Parental-based prevention interventions to reduce suicidal-related behaviours in adolescents: protocol for a systematic review and meta-analysis [0.03%]
Daniel Núñez,Fabiola Salas,Jorge Gaete et al.
Daniel Núñez et al.
Introduction: Effectiveness of prevention programmes to reduce suicidal-related behaviours among adolescents could improve when systematically involve interventions for parents/caregivers to enhance family functioning and...
Understanding tonic and phasic irritability in developmental psychopathology among help-seeking children and adolescents in Switzerland: Protocol for the longitudinal multimodal UTOPICA study [0.03%]
Sebastien Urben,Julia Giovannini,Aline Dietsche et al.
Sebastien Urben et al.
Introduction: Irritability represents one of the most common causes of referral to child and adolescent mental health services. Conceptually, tonic irritability (i.e., persistent grumpy mood) can be distinguished from pha...
Effects of nurse-led shared decision-making on low-dose CT uptake and screening outcomes in high-risk populations: a systematic review and meta-analysis [0.03%]
Xiumei Tang,Tingqian Cao,Wenchong He et al.
Xiumei Tang et al.
Objectives: To evaluate the effects of nurse-led shared decision-making (SDM) on lung cancer screening outcomes, including low-dose CT (LDCT) uptake, benign findings, early cancer detection and willingness to participate ...
Meta-Analysis
BMJ open. 2026 Apr 22;16(4):e113486. DOI:10.1136/bmjopen-2025-113486 2026
LEAN mass Preservation with Resistance Exercise and Protein during semaglutide and tirzepatide therapy (LEAN-PREP study): a protocol for a randomised controlled trial [0.03%]
Ameenah A Alawadhi,Dherar Alroudhan,Dalal J Alsaeed et al.
Ameenah A Alawadhi et al.
Introduction: Obesity is a global public health issue, with its effects a particular issue in Kuwait. Advances in pharmaceutical treatment (eg, glucagon-like peptide-1s) offer an effective solution, with the magnitude of ...
Challenges in translating GINA asthma recommendations into practice: a qualitative study of healthcare professionals in Jordan [0.03%]
Anas Abed,Arwa Omar Al Khatib
Anas Abed
Objectives: To explore barriers and enablers to the implementation of the Global Initiative for Asthma (GINA) recommendations in Jordan, building on prior quantitative survey findings. We aimed to examine healthcare profe...
Improving menstrual and vaginal health for all (IMVAHA): protocol for a randomised cross-over trial assessing the impact of menstrual products on the vaginal microbiome of women aged 18-35 years in Cameroon, Peru and Switzerland [0.03%]
Monica R Ticlla,Mari Dumbaugh,Sandra Condori-Catachura et al.
Monica R Ticlla et al.
Introduction: Menstrual health is critical to achieving gender equity and reaching the 2030 Sustainable Development Goals, yet evidence on the health impacts of menstrual products-particularly on the vaginal microbiota-is...
Participatory priority setting of research questions for improving hospital care of adults with childhood-onset intellectual disabilities (PRISMA): a study protocol for a mixed-methods study [0.03%]
Antonia Scheffel,Tanja Fritsch,Susanne Arnold et al.
Antonia Scheffel et al.
Introduction: Persons with childhood-onset intellectual or complex disabilities have an elevated probability of encountering delayed or erroneous diagnoses during hospital treatment. It is imperative to consider the possi...
Assessing the impact, uptake and use of reporting guidelines for patient and public involvement in research: GRIPP2 - study protocol for a meta-research project [0.03%]
Ferrán Catalá-López,Ernesto Ganuza,Adolfo Alonso-Arroyo et al.
Ferrán Catalá-López et al.
Introduction: Patient and public involvement (PPI) in research is increasingly recognised for its potential to enhance feasibility, improve relevance and foster collaboration at different stages of a study. Reporting guid...