Palladium Catalyzed Aryl C-H Amination with O2 via In Situ Formation of Peroxide-Based Oxidant(s) from Dioxane [0.03%]
通过Dioxane的原位生成氧化剂实现O2介导的钯催化芳烃C-H氨氧化学反应
Adam B Weinstein,Shannon S Stahl
Adam B Weinstein
(DAF)Pd(OAc)2 (DAF = 4,5-diazafluorenone) catalyzes aerobic intramolecular aryl C-H amination with N-benzenesulfonyl-2-aminobiphenyl in dioxane to afford the corresponding carbazole product. Mechanistic studies show that the reaction involv...
P450-catalyzed asymmetric cyclopropanation of electron-deficient olefins under aerobic conditions [0.03%]
电子贫乏烯烃的有氧条件下P450催化环丙烷化反应中的不对称合成
Hans Renata,Z Jane Wang,Rebekah Z Kitto et al.
Hans Renata et al.
A variant of P450 from Bacillus megaterium five mutations away from wild type is a highly active catalyst for cyclopropanation of a variety of acrylamide and acrylate olefins with ethyl diazoacetate (EDA). The very high rate of reaction ena...