Plasma choline metabolites associate with metabolic stress among young overweight men in a genotype-specific manner [0.03%]
年轻超重男性中的血浆胆碱代谢物以基因型特异性的方式与代谢压力相关联
J Yan,L B Winter,B Burns-Whitmore et al.
J Yan et al.
Objectives: We aimed to test the hypotheses that (i) plasma choline metabolites differ between normal (body mass index (BMI)
Estimation of genetic effects on BMI during adolescence in an ethnically diverse cohort: The National Longitudinal Study of Adolescent Health [0.03%]
遗传效应在美国民族多样性的青少年队列中对体质指数的影响评估：全国青少年健康纵向研究数据分析
M Graff,K E North,K L Mohlke et al.
M Graff et al.
Objective: The contribution of genetic variants to body mass index (BMI) during adolescence across multiethnic samples is largely unknown. We selected genetic loci associated with BMI or obesity in European-descent sample...
Abdominal obesity and mortality: The Pennington Center Longitudinal Study [0.03%]
腹部肥胖和死亡率：彭宁顿中心纵向研究结果
P T Katzmarzyk,E Mire,C Bouchard
P T Katzmarzyk
The purpose of this study was to determine the association between visceral adipose tissue (VAT) and all-cause mortality. The sample included 1089 white men and women 18-84 years of age from the Pennington Center Longitudinal Study, a prosp...
C H Sandholt,T Hansen,O Pedersen
C H Sandholt
Obesity and related complications are major health burdens. Almost 700 million adults are currently obese globally and the prevalence is predicted to rise towards 2030. The sudden change of lifestyle with physical inactivity and excessive c...
Menin liver-specific hemizygous mice challenged with high fat diet show increased weight gain and markers of metabolic impairment [0.03%]
男性肝特异性半单倍体小鼠高脂肪饮食后体重增加和代谢障碍标志物升高
L Wuescher,K Angevine,P R Patel et al.
L Wuescher et al.
Objective: The menin tumor suppressor protein is abundantly expressed in the liver, although no function has been identified because of lack of tumor development in multiple endocrine neoplasia type 1 (Men1) null livers. ...
Wheat-derived arabinoxylan oligosaccharides with prebiotic effect increase satietogenic gut peptides and reduce metabolic endotoxemia in diet-induced obese mice [0.03%]
一种具有益生元作用的 wheat-derived arabinoxylan 寡糖通过增加饱腹感肠道多肽和减少代谢性内毒素血症来改善由饮食诱导的小鼠肥胖症状的研究
A M Neyrinck,V F Van Hée,N Piront et al.
A M Neyrinck et al.
Background: Alterations in the composition of gut microbiota -known as dysbiosis- have been proposed to contribute to the development of obesity, thereby supporting the potential interest of nutrients acting on the gut mi...
B Perry,Y Wang
B Perry
The overwhelming increase in the prevalence of overweight and obesity in recent years represents one of the greatest threats to the health of the developed world. Among current treatments, however, gastrointestinal (GI) surgery remains the ...
Abdominal adiposity and daily step counts as determinants of glycemic control in a cohort of patients with type 2 diabetes mellitus [0.03%]
腹型肥胖和每日步数对2型糖尿病患者血糖控制的影响
P Manjoo,L Joseph,K Dasgupta
P Manjoo
Objective: Favorable effects of walking levels on glycemic control have been hypothesized to be mediated through reductions in abdominal adiposity, but this has not been well studied. We addressed this issue in patients t...
Proximal correlates of metabolic phenotypes during 'at-risk' and 'case' stages of the metabolic disease continuum [0.03%]
代谢性疾病连续体的“高危”和“病例”阶段的代谢表型的临近相关因素
M T Haren,G Misan,J F Grant et al.
M T Haren et al.
Objective: To examine the social and behavioural correlates of metabolic phenotypes during 'at-risk' and 'case' stages of the metabolic disease continuum. ...
M Caron-Jobin,D Mauvoisin,A Michaud et al.
M Caron-Jobin et al.
Objective: Subcutaneous (SC) adipose tissue stearic acid (18:0) content and stearoyl-CoA desaturase-1 (SCD1)-mediated production of oleic acid (18:1) have been suggested to be altered in obesity. The objective of our stud...