Global burden of 13 non-communicable diseases attributable to high fasting plasma glucose from the GBD 2021 study [0.03%]
2021年全球疾病负担研究中归因于高空腹血糖的13种非传染性疾病疾病负担
Junfeng Zhou,Zhengbin Yao,Shugen Xu et al.
Junfeng Zhou et al.
Background and objective: High fasting plasma glucose (HFPG) is a major risk factor for diseases, posing a serious public health challenge. This study examines the global burden of 13 non-communicable diseases (NCDs) attr...
Pre-clinical studies show anti-diabetic effect of INSPARIN, a protein derived from the E4orf1 gene of a human adenovirus [0.03%]
临床前期研究显示：源自人类腺病毒的E4orf1基因的蛋白质INSPARIN具有抗糖尿病作用
Md Abu Bakkar Siddik,Zahra Feizy,Masoud Nateqi et al.
Md Abu Bakkar Siddik et al.
Background: Human adenovirus Ad36-derived protein, termed INSPARIN, up-regulates cellular glucose uptake through insulin-independent cell signaling. Transgenic or viral vector mediated delivery of INSPARIN exhibits signif...
Umbelliferone preserves skin epidermal barrier integrity in diabetes-induced keratinocytes by regulating actin dynamics and suppressing ROS-mediated apoptosis [0.03%]
伞形素通过调节肌动蛋白动力学并抑制糖尿病诱导的角质形成细胞中ROS介导的凋亡来维持皮肤表皮屏障的完整性
Dong Yeon Kim,Young-Hee Kang,Min-Kyung Kang
Dong Yeon Kim
Background: The skin serves as a fundamental protective barrier against environmental insults, with the epidermis, particularly the stratum corneum and tight junctions (TJs) connecting keratinocytes, playing a crucial rol...
Designing GLP-1 delivery: structural perspectives and formulation approaches for optimized therapy [0.03%]
GLP-1给药设计：优化治疗的结构观点与制剂方法
Ravi Vamsi Peri,Harsh Anchan,Kamal Jonnalagadda et al.
Ravi Vamsi Peri et al.
GLP-1 and its synthetic analogs have emerged as significant therapeutic agents for the management of metabolic disorders, merging glycemic control with weight loss through innovative structural and delivery breakthroughs. This review provid...
Bedtime snacking and glycemic deterioration in young children with Type 1 diabetes on multiple daily injections: a randomized controlled crossover trial [0.03%]
学龄前1型糖尿病每天多次注射胰岛素患儿睡前加餐对高血糖恶化的影响：交叉试验研究
Tuğba Gökçe,Kağan Ege Karakuş,Gül Yeşiltepe Mutlu et al.
Tuğba Gökçe et al.
Objective: To determine if a bedtime snack in young children with type 1 diabetes (T1D) prevents nocturnal hypoglycemia, and the impact on glycemia overnight. ...
Randomized Controlled Trial
Nutrition & diabetes. 2025 Nov 21;15(1):49. DOI:10.1038/s41387-025-00392-9 2025
Dosage exploration of the effects of honey and its derivatives on cardiometabolic outcomes: an overview of systematic reviews and GRADE-assessed updated meta-analysis [0.03%]
蜂蜜及其衍生物对心血管代谢结局影响的剂量效应研究：系统评价和GRADE分级的meta分析更新摘要
Mostafa Norouzzadeh,Sanaz Barazandeh,Minoo Hasan Rashedi et al.
Mostafa Norouzzadeh et al.
Cardiovascular diseases and diabetes are associated with significant mortality, morbidity, and economic burden, highlighting the need for alternative preventive strategies. Honey bee products, including honey, royal jelly, and propolis, are...
Long-term time in target range for body mass index (BMI) and diabetes incidence: insights from CHARLS [0.03%]
基于CHARLS的长期目标范围内体质指数(BMI)与糖尿病发病率关系研究
Chao Chu,Yan Zhang,Fuxue Deng et al.
Chao Chu et al.
Background: Body mass index (BMI) is strongly associated with the development of type 2 diabetes. However, the association between long-term time in target range (TTR) for BMI and the incidence of new-onset diabetes remai...
Can high-protein diabetes-specific oral nutritional supplements improve postprandial glycemic response in prediabetes? An open-label, cross-over clinical trial [0.03%]
高蛋白糖尿病专用口服营养补充剂可改善糖耐量受损的餐后血糖反应吗？一项开放标签交叉临床试验
Yeongtaek Hwang,Minkyung Bok,Suk Chon et al.
Yeongtaek Hwang et al.
Background: Prediabetes is becoming increasingly widespread and often progresses to diabetes, thereby raising the risk of severe complications. High-protein diets, known to improve glucose control and prevent diabetes, ca...
Clinical Trial
Nutrition & diabetes. 2025 Nov 17;15(1):47. DOI:10.1038/s41387-025-00399-2 2025
Association of GAS6, AXL, and GAS6-AS lncRNAs with nephropathy in Egyptian patients with type 2 diabetes mellitus: a case-control observational study [0.03%]
GAS6，AXL和GAS6-AS长链RNA与埃及2型糖尿病患者肾病的关系：一项病例对照观察研究
Tarek Kamal Motawi,Dina Sabry,Nancy Mamdouh Ahmed et al.
Tarek Kamal Motawi et al.
Background/objectives: Diabetic nephropathy (DN) is a prevalent microvascular diabetic complication that is not totally unveiled. In this study, we considered GAS6, AXL, GAS6-AS1, and GAS6-DT as possible early diagnostic ...
Observational Study
Nutrition & diabetes. 2025 Nov 13;15(1):45. DOI:10.1038/s41387-025-00400-y 2025
Does partial replacement of animal protein with plant protein in the diet affect components of metabolic syndrome, adropin levels, and the atherogenic index of plasma? Results from a parallel randomized clinical trial in adults with metabolic syndrome [0.03%]
用植物蛋白部分替代动物蛋白对代谢综合征组分、adropin水平和血浆致动脉粥样硬化指数的影响：一项并行随机对照试验结果
Farnaz Shahdadian,Mahsa Rezazadegan,Parisa Rouhani et al.
Farnaz Shahdadian et al.
Background: Few studies evaluated the effect of different proportions of dietary plant- and animal-based protein on metabolic syndrome (MetS) and its related biomarkers. ...
Randomized Controlled Trial
Nutrition & diabetes. 2025 Oct 27;15(1):43. DOI:10.1038/s41387-025-00401-x 2025