Central obesity in males affected by a dyslipidemia-associated genetic polymorphism on APOA1/C3/A4/A5 gene cluster [0.03%]
脂质代谢相关基因APOA1/C3/A4/A5多态性男性携带者中心型肥胖特点分析
M-C Hsu,C-S Chang,K-T Lee et al.
M-C Hsu et al.
Background: Central obesity is a rising epidemic, and often occurs in parallel with dyslipidemia. Furthermore, enhancement of ectopic fat deposition has been observed in both human studies and animal models of altered lip...
Cannabinoid type 1 receptor mediates depot-specific effects on differentiation, inflammation and oxidative metabolism in inguinal and epididymal white adipocytes [0.03%]
大麻素受体1介导的大鼠腹股沟和附睾白色脂肪细胞分化、炎症及氧化代谢的脂库特异性效应
I V Wagner,N Perwitz,M Drenckhan et al.
I V Wagner et al.
Objective: The endocannabinoid system is a major component in the control of energy metabolism. Cannabinoid 1 (CB1)-receptor blockade induces weight loss and reduces the risk to develop the metabolic syndrome with its ass...
Eating dark and milk chocolate: a randomized crossover study of effects on appetite and energy intake [0.03%]
食用深巧克力和牛奶巧克力：对摄食欲望及能量摄入的随机交叉试验研究
L B Sørensen,A Astrup
L B Sørensen
Objective: To compare the effect of dark and milk chocolate on appetite sensations and energy intake at an ad libitum test meal in healthy, normal-weight men. ...
Long-term effect of lifestyle intervention on adiposity, metabolic parameters, inflammation and physical fitness in obese children: a randomized controlled trial [0.03%]
肥胖儿童生活方式干预对体脂、代谢参数、炎症和体质的长期影响：一项随机对照试验
R C Vos,J M Wit,H Pijl et al.
R C Vos et al.
Background: Behavioral lifestyle intervention, combined with parental involvement, is preferred over standard care or self-help in childhood obesity. The short-term results of such interventions are promising, but long-te...
Serum adiponectin level is not only decreased in metabolic syndrome but also in borderline metabolic abnormalities [0.03%]
血清脂联素水平不仅在代谢综合征中降低，在临界代谢异常中也降低
M Y Baden,Y Yamada,Y Obata et al.
M Y Baden et al.
Objective: Along with the increasing prevalence of obesity and related diseases, particularly atherosclerotic diseases, metabolic syndrome (MetS) is now a common and major public health issue in many countries around the ...
Effect of moderate weight loss on hepatic, pancreatic and visceral lipids in obese subjects [0.03%]
中度减肥对肥胖者肝脏、胰腺和内脏脂肪的影响
A P Rossi,F Fantin,G A Zamboni et al.
A P Rossi et al.
Objective: To compare the effects of weight loss on visceral and subcutaneous abdominal fat, liver and pancreas lipid content and to test the effects of these changes on metabolic improvement observed after weight loss. ...
A proposed potential role for increasing atmospheric CO2 as a promoter of weight gain and obesity [0.03%]
二氧化碳促进体重增加和肥胖的潜在作用机制探讨
L-G Hersoug,A Sjödin,A Astrup
L-G Hersoug
Human obesity has evolved into a global epidemic. Interestingly, a similar trend has been observed in many animal species, although diet composition, food availability and physical activity have essentially remained unchanged. This suggests...
Relation of depot-specific adipose inflammation to insulin resistance in human obesity [0.03%]
人体肥胖中脂肪组织特异性脂肪炎症与胰岛素抵抗的关系
S J Bigornia,M G Farb,M M Mott et al.
S J Bigornia et al.
Background: A low-grade state of adipose tissue inflammation associated with obesity has been linked to mechanisms of systemic metabolic dysfunction. However, the relation of clinical phenotypes to depot-specific inflamma...
C K Tan,H C Chong,E H P Tan et al.
C K Tan et al.
Recent findings on the role of transforming growth factor (TGF)-β/Smad3 signaling in the pathogenesis of obesity and type 2 diabetes have underscored its importance in metabolism and adiposity. Indeed, elevated TGF-β has been previously r...
Increased vegetable and fruit consumption during weight loss effort correlates with increased weight and fat loss [0.03%]
减重过程中增加果蔬的摄入与更大的体重和体脂减少相关性增强
L D Whigham,A R Valentine,L K Johnson et al.
L D Whigham et al.
Background: Individuals who focused on calorie counting lost more weight than those who focused on increasing vegetable and fruit (V&F) intake in a weight loss program. We now present serum carotenoid data (biomarkers of ...