Isobavachin inhibits osteoclastogenesis in inflammatory osteolysis loss by modulating the ROS-mediated Nrf2/HO-1 signaling pathway [0.03%]
异巴瓦灵通过调节ROS介导的Nrf2/HO-1信号通路抑制炎性骨溶解中的破骨细胞生成
Liang Liao,Yunde Xu,Jindeng Liao et al.
Liang Liao et al.
Objectives: Isobavachin (Ibv), a monomeric compound derived from a traditional Chinese herb, demonstrates a range of biological activities. However, the precise effects of Ibv on inflammatory osteolysis remain inadequatel...
Rutin enhances the analgesic efficacy of low-dose pregabalin without sedative side effects in a rat model of chronic constriction injury [0.03%]
rutin通过增强低剂量普瑞巴林的镇痛效应而不用考虑其催眠副作用:慢性约束损伤大鼠模型的研究
Gülsüm Helvacı,Rana Arslan,Nurcan Bektaş
Gülsüm Helvacı
Objectives: The aim of this study was to evaluate the antiallodynic and antihyperalgesic effects of rutin alone and in combination with pregabalin in a chronic constriction injury-induced neuropathic pain model. ...
Protective effect of cornel iridoid glycoside against isoniazid- and rifampicin- induced liver injury via regulating JAK/STAT pathway [0.03%]
Cornel 玄参属.iridoid 伊洛朵类.glycosides 多糖对抗异烟肼和利福平引起的肝损伤的保护作用通过调节 JAK/STAT 途径实现
Jia Liu,Xiao Han,Yumei Li et al.
Jia Liu et al.
Background: Hepatotoxicity associated with Isoniazid (INH) and Rifampicin (RIF) is one of the major impediments in antituberculosis therapy. Purpose: ...
Correction to: Improving the oral bioavailability and anti-inflammatory potential of clove oil-derived β-caryophyllene with a self-nanoemulsifying drug delivery system [0.03%]
Correction to:利用自微乳化药物递送系统改进肉桂油衍生物β- Caryophyllene的口服生物利用度和抗炎潜能
Published Erratum
The Journal of pharmacy and pharmacology. 2026 May 2;78(5):rgag053. DOI:10.1093/jpp/rgag053 2026
Viscoelastic properties of polymer mixtures containing micro-ribbons and microfibres for the 3D printing of pharmaceutical dosage forms by fused deposition modelling [0.03%]
含微 ribbon 和微纤维的聚合物混合物的粘弹性以及融合沉积模型的药物剂型的3D打印性质研究
Marwan Algellay,Satyajit D Sarker,Matthew Roberts et al.
Marwan Algellay et al.
Objectives: To match the disintegration time of conventional oral films with 3D printed fast-dissolving oral films (FDFs), micro-composites have been used in the formulation. However, in certain cases the 3D-printer faile...
Effect of Tribulus terrestris L. extract in the management of polycystic ovarian syndrome in rat model [0.03%]
霸王花提取物治疗多囊卵巢综合征模型大鼠的疗效研究
Hadia Abdul Qayyum,Haseeb Anwar,Ghulam Hussain et al.
Hadia Abdul Qayyum et al.
Objectives: Oxidative stress is considered to be a significant factor in the complex disorder known as polycystic ovarian syndrome (PCOS). In this study, we investigated whether using the traditional medicinal plant Tribu...
Modulation of vascular remodeling and vasoconstriction by α-phellandrene in hypoxia-induced pulmonary hypertension [0.03%]
α-冰片通过调节缺氧性肺动脉高压的血管重塑和血管收缩的作用机制研究
Zhan Ting Yang,Yi Wen Wang,Hai Jun Bai et al.
Zhan Ting Yang et al.
Objectives: This study investigated α-phellandrene (PE)'s therapeutic effects on hypoxia-induced pulmonary hypertension (HPH), with emphasis on pulmonary vasoconstriction and vascular remodeling. ...
A novel Platycladus orientalis essential oil with functional properties: antioxidant defense, cognitive improvement, and immune enhancement for potential nutraceutical use [0.03%]
一种具有功能性的新型侧柏叶精油:抗氧化防御、认知改善和免疫增强的潜在营养补充剂用途研究
Mengyuan Zhu,Xuanqi Fu,Yue Lv et al.
Mengyuan Zhu et al.
Context: A specialized essential oil extracted from the heartwood of Platycladus orientalis via supercritical CO₂ extraction shows distinct chemical and physicochemical properties compared with conventional leaf-derived ...
Oleanolic acid ameliorates collagen induced arthritis in rats through the gut microbiota [0.03%]
白桦酸通过肠道菌群改善胶原诱导的大鼠关节炎
Chipu Liu,Yue Zhao,Xiaoran Su et al.
Chipu Liu et al.
Objectives: Oleanolic acid (OA) is a natural anti-inflammatory triterpenoid. This study investigates its therapeutic potential against rheumatoid arthritis (RA), a chronic autoimmune condition characterized by inflammator...
Cynandione A improves white adipose tissue homeostasis in high-fat diet-fed mice [0.03%]
肉食饲养老鼠的白色脂肪组织稳态的类黄酮氰化豆稀酮A的作用机制研究
Atsushi Sawamoto,Misaki Shiba,Satoshi Okuyama et al.
Atsushi Sawamoto et al.
Objectives: Cynandione A (CA), a major bioactive compound isolated from Cynanchum wilfordii Radix, is a crude drug traditionally used in East Asia. We have previously demonstrated that CA induces a beige adipocyte-like ph...