Tezepelumab in Chinese Patients With Severe Chronic Rhinosinusitis With Nasal Polyps: A Prespecified Subgroup Analysis of the Phase 3 WAYPOINT Trial [0.03%]
针对严重慢性鼻窦炎伴鼻息肉的中国患者开展特苏培尤姆单抗治疗的III期WAYPOINT试验预设亚组分析
Li Hu,Houyong Li,Xicai Sun et al.
Li Hu et al.
Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) in Chinese patients often exhibits a mixed Type 1/2/3 inflammatory phenotype (63%), potentially impacting the efficacy of biologics targeting Type 2 inflammati...
Reply to: Comment on "Female-Specific Risk of TAS2R Variants in Chronic Rhinosinusitis: A Hospital-Based Cohort Study From the Taiwan Precision Medicine Initiative" [0.03%]
关于“台湾精准医学计划医院队列研究中慢性鼻窦炎的TAQR2变异女性特异性风险”的评论回复
Rong-San Jiang,Yi-Chen Chen
Rong-San Jiang
Correlation of Local Nasal Biomarkers and Olfactory Dysfunction in Chronic Rhinosinusitis: A Systematic Review and Meta-Analysis [0.03%]
慢性鼻窦炎局部鼻生物标志物与嗅觉障碍相关性的系统评价和meta分析
David Kayekjian,Neeti Gandra,Shaun A Nguyen et al.
David Kayekjian et al.
Background: To systematically evaluate the local biomarkers correlated with olfactory dysfunction (OD) in chronic rhinosinusitis (CRS). Methods: ...
Persistent Smell and Taste Disorders in the Post-COVID-19 Pandemic Era: A Cross-National Study of Prevalence and Quality of Life in the UK and the USA [0.03%]
后新冠肺炎时代持续性嗅觉和味觉障碍的跨国研究：英国和美国患病率及生活质量的差异
Umar Rehman,Zi Jian Lau,Carl Philpott et al.
Umar Rehman et al.
Anosmia/hyposmia affected 14.8%-19.6% of participants in the UK and the USA in the post-pandemic era. Since symptom onset, 37.1%-48.8% of affected participants reported no improvement, while 15.3%-17.6% reported worsening symptoms. Anosmia/...
Alison J Yu,Kristina A LaPointe,Kaitlyn Ann Roberts et al.
Alison J Yu et al.
Nearly two-thirds of patients had no surgery or incomplete sinus surgery before biologics. Among all sinuses, the frontal sinus was the least frequently addressed before biologics. ...
Deep Learning Improves Sensitivity to Change in Sinus Computed Tomography: Evidence From Two Randomized Controlled Trials [0.03%]
深度学习改善窦部CT影像变化的检出：两项随机对照试验证据
James W MacKay,Lars H Nordenmark,Sofia Necander et al.
James W MacKay et al.
Parosmia Beyond Olfactory Loss: A Propensity Score-Matched Study of Central Sensitization-Associated Comorbidities [0.03%]
中枢敏感性相关共病的倾向评分匹配研究：不仅仅是嗅觉丧失的味觉异常气味体验
Elay Amidor,Nidal Muhanna,Avraham Abergel et al.
Elay Amidor et al.
Parosmia is linked to migraine, chronic pain, fibromyalgia, and hypersomnia beyond anosmia. Central sensitization comorbidities distinguish parosmia from quantitative olfactory loss. Findings support parosmia as a disorder of altered centra...
Chronic Rhinosinusitis and Nasal Polyps in Eosinophilic Granulomatosis With Polyangiitis: A Scoping Review [0.03%]
嗜酸性肉芽肿伴聚动脉炎的慢性鼻窦炎和鼻息肉：系统评价
Alisha Sharma,Alyssa Y Li,Teruko Kishibe et al.
Alisha Sharma et al.
Background: Chronic rhinosinusitis (CRS) is one of the most common manifestations of eosinophilic granulomatosis with polyangiitis (EGPA), often preceding the diagnosis of systemic vasculitis by several years. The sinonas...
Early Versus Late Recurrence in Olfactory Neuroblastoma: A Multi-Institutional Analysis of Predictive Risk Factors [0.03%]
嗅神经母细胞瘤早期复发与晚期复发的多中心分析预测危险因素
Alexandria Harris,Anthony Tang,Nicholas Fung et al.
Alexandria Harris et al.
Background: Olfactory neuroblastoma (ONB) exhibits variable recurrence patterns, with significant late recurrences occurring years after treatment. We investigated cutoff periods to define late recurrence and identified p...