Wheat peptide alleviates DSS-induced colitis by activating the Keap1-Nrf2 signaling pathway and maintaining the integrity of the gut barrier [0.03%]
wheat肽通过激活Keap1-Nrf2信号通路并维持肠道屏障的完整性来缓解DSS诱导的结肠炎
Wen-Yin Xie,Zhong-Hao Ji,Wen-Zhi Ren et al.
Wen-Yin Xie et al.
Inflammatory bowel disease (IBD) is difficult to cure, and formulating a dietary plan is an effective means to prevent and treat this disease. Wheat peptide contains a variety of bioactive peptides with anti-inflammatory and antioxidant fun...
(+)-Catechin ameliorates diabetic nephropathy injury by inhibiting endoplasmic reticulum stress-related NLRP3-mediated inflammation [0.03%]
（+-）儿茶素通过抑制内质网应激相关的NLRP3介导的炎症改善糖尿病肾病损伤
Xiwen Zhang,Zhihao Huo,Xiaotong Jia et al.
Xiwen Zhang et al.
Endoplasmic reticulum (ER) stress and chronic sterile inflammation are associated with the pathogenesis of diabetic nephropathy (DN). Catechins are natural polyphenolic compounds found in green tea that possess some health benefits. However...
Protective effects of EGCG on acrolein-induced Caenorhabditis elegans and its mechanism of life extension [0.03%]
EGCG对丙烯醛诱导的秀丽隐杆线虫的保护作用及寿命延长机制研究
Yiming Song,Danyang Liu,Jiayan Xie et al.
Yiming Song et al.
In this study, it was found that epigallocatechin-3-gallate (EGCG) could extend the lifespan of Caenorhabditis elegans (C. elegans) induced by 100 μM acrolein (ACR) at all test concentrations (300, 400, 500, 600, and 700 μM). Notably, 500...
The protective role of water intake in age-related eye diseases: insights from a Mendelian randomization study [0.03%]
基于孟德尔随机化研究的饮水摄入在年龄相关性眼病中的保护作用分析
Yuze Mi,Qinnan Zhu,Xinni Zheng et al.
Yuze Mi et al.
Age-related eye diseases (AREDs), including age-related cataracts (ARCs), age-related macular degeneration (AMD), diabetic retinopathy (DR), and glaucoma, are a leading cause of visual loss globally. This study aimed to explore the effects ...
In vitro protein digestibility of RuBisCO-enriched wheat dough: a comparative study with pea and gluten proteins [0.03%]
Rubisco富集的小麦面团体外蛋白消化率与豌豆和麦胶蛋白的比较研究
Maude Ducrocq,Adeline Boire,Claire Bourlieu-Lacanal et al.
Maude Ducrocq et al.
Growing demand for sustainable, plant-based protein sources has stimulated interest in new ingredients for food enrichment. This study investigates the nutritional and digestive implications of enriching wheat dough with RuBisCO, in compari...
Comparative Study
Food & function. 2024 May 7;15(9):5132-5146. DOI:10.1039/d3fo05652j 2024
Colon-available mango (poly)phenols exhibit mitigating effects on the intestinal barrier function in human intestinal cell monolayers under inflammatory conditions [0.03%]
肠道炎症条件下肠道细胞单层上可用结肠的芒果(聚)酚对肠道屏障功能的影响缓解作用
Gema Pereira-Caro,Salud Cáceres-Jiménez,Alicia Moreno-Ortega et al.
Gema Pereira-Caro et al.
This study investigated the impact of in vivo available colon-mango (poly)phenols on stress-induced impairment of intestinal barrier function. Caco-2/HT29-MTX cells were incubated with six extracts of ileal fluid collected pre- and 4-8 h po...
Eicosapentaenoic acid activates the P62/KEAP1/NRF2 pathway for the prevention of diabetes-associated cognitive dysfunction [0.03%]
二十碳五烯酸通过激活P62/KEAP1/NRF2通路预防糖尿病相关的认知障碍
Ao Tian,Yan Zheng,Hui Li et al.
Ao Tian et al.
Diabetes-associated cognitive dysfunction (DCD) is a severe complication of diabetes mellitus (DM), threatening the life quality of the diabetic population. However, there is still a lack of effective approaches for its intervention. Eicosa...
Hydroxytyrosol ameliorates stress-induced liver injury through activating autophagy via HDAC1/2 inhibition [0.03%]
羟基酪醇通过HDAC1/2抑制激活自噬来改善应激引起的肝损伤
Li Fan,Lijuan Zhao,Yangbo Zhu et al.
Li Fan et al.
Hydroxytyrosol (HT), a phenolic extra-virgin olive oil compound used as a food supplement, has been recognized to protect liver function and alleviate stress-induced depressive-like behaviors. However, its protective effects against stress-...
The dairy-derived peptide Miltin exerts anti-obesity effects by increasing adipocyte thermogenesis [0.03%]
dairy-derived肽Miltin通过增加脂肪细胞产热来发挥减肥效果
Hong Zhong,Xiaoxiao Zhang,Yangyang Wu et al.
Hong Zhong et al.
Growing research has highlighted that the consumption of dairy products improves the metabolic health in obese individuals by functioning as regulatory modulators. However, the molecular basis of this effect remains largely unknown. Herein,...
Taurocholic acid ameliorates hypertension through the activation of TGR5 in the hypothalamic paraventricular nucleus [0.03%]
牛复合胆酸通过激活下丘脑室旁核的TGR5来改善高血压
Ying Li,Ya-Nan Gao,Ying-Bao Zhu et al.
Ying Li et al.
Diets rich in taurine can increase the production of taurine-conjugated bile acids, which are known to exert antihypertensive effects. Despite their benefits to the heart, kidney and arteries, their role in the central nervous system during...