Lactobacillus reuteri JCM 1112 ameliorates chronic acrylamide-induced glucose metabolism disorder via the bile acid-TGR5-GLP-1 axis and modulates intestinal oxidative stress in mice [0.03%]
罗伊氏乳杆菌JCM 1112通过胆汁酸-TGR5-GLP-1轴改善丙烯酰胺诱导的慢性糖代谢紊乱并调节小鼠肠道氧化应激反应
Zonghao Yue,Feiyue Zhao,Yuqi Guo et al.
Zonghao Yue et al.
Acrylamide (AA) is a toxic food contaminant that has been reported to cause glucose metabolism disorders (GMD) at high doses. However, it is unclear whether chronic low-dose AA can induce GMD and whether probiotics can alleviate AA-induced ...
Intestinal absorption of bioactive oligopeptides: paracellular transport and tight junction modulation [0.03%]
生物活性寡肽的肠道吸收：旁路转运和紧密连接调节
Zhipeng Yu,Di Liu,Chunjian Wu et al.
Zhipeng Yu et al.
Bioactive oligopeptides have gained increasing attention due to their diverse physiological functions, and these can be transported into the vasculature via transcellular and paracellular pathways. Among these, paracellular transport throug...
Efficacy and safety of galacto-oligosaccharide in the treatment of functional constipation: randomized clinical trial [0.03%]
益生元低聚半乳糖治疗功能性便秘的疗效和安全性：随机临床试验
Jae-Hwan Lee,Geun-Bae Kim,Kisoo Han et al.
Jae-Hwan Lee et al.
The efficacy and safety of galacto-oligosaccharides (GOS) in treating functional constipation were evaluated in a four-week randomized, double-blind clinical trial on 63 patients who met Rome IV criteria (34 GOS, 29 placebo group). The numb...
Randomized Controlled Trial
Food & function. 2024 Jun 17;15(12):6374-6382. DOI:10.1039/d4fo00999a 2024
Fucoxanthin alleviates lipopolysaccharide-induced intestinal barrier injury in mice [0.03%]
富足黄素缓解脂多糖诱导的小鼠肠道屏障损伤作用
Lei Du,Chen Chen,Yu-Hong Yang et al.
Lei Du et al.
The aim of this study was to evaluate the preventive role and underlying mechanisms of fucoxanthin (Fx) on lipopolysaccharide (LPS)-induced intestinal barrier injury in mice. Our results demonstrated that the oral administration of Fx (50 a...
Advances in the composition, efficacy, and mimicking of human milk phospholipids [0.03%]
人类乳脂磷脂的组成、功效及模拟研究进展
Yuru Wang,Qian Liu,Yan Liu et al.
Yuru Wang et al.
Phospholipids are the essential components of human milk, contributing to the enhancement of cognitive development, regulation of immune functions, and mitigation of elevated cholesterol levels. Infant formulas supplemented with phospholipi...
Gut microbiota-bile acid axis mediated the beneficial associations between dietary lignans and hyperuricemia: a prospective study [0.03%]
膳食木脂素通过肠道菌群-胆汁酸轴介导的与高尿酸血症之间有益关联：一项前瞻性研究
Lai-Bao Zhuo,Yingdi Yang,Congmei Xiao et al.
Lai-Bao Zhuo et al.
Background: The escalating prevalence of hyperuricemia is emerging as a significant public health concern. The association between dietary lignans and hyperuricemia is yet to be fully elucidated. Our study aims to evaluate the relationships...
Anti-obesity effects of a standardized ethanol extract of Eisenia bicyclis by regulating the AMPK signaling pathway in 3T3-L1 cells and HFD-induced mice [0.03%]
地木耳标准化乙醇提取物通过调节AMPK信号通路发挥抗肥胖作用
Young-Seo Yoon,Kyung-Sook Chung,Su-Yeon Lee et al.
Young-Seo Yoon et al.
Obesity requires treatment to mitigate the potential development of further metabolic disorders, including diabetes, hyperlipidemia, tumor growth, and non-alcoholic fatty liver disease. We investigated the anti-obesity effect of a 30% ethan...
Compressed fluid-based technology for downstream isolation of bluish anthocyanin-derived pigments obtained from blueberry surplus [0.03%]
基于压缩流体技术的从蓝莓废弃物中提取蓝色花色苷色素的下游分离工艺
Ana N Nunes,Joana Oliveira,Maria Rosário Bronze et al.
Ana N Nunes et al.
A dynamic compressed fluid-based separation process combining carbon dioxide and ethanol was explored to isolate portisins previously hemi-synthesized from blueberry surplus anthocyanins. The influence of process parameters such as pressure...
The effectiveness of probiotics as an adjunct therapy in patients under mechanical ventilation: an umbrella systematic review and meta-analysis [0.03%]
益生菌作为机械通气患者辅助治疗的有效性：伞状系统评价和meta分析
Paniz Anvarifard,Maryam Anbari,Faezeh Ghalichi et al.
Paniz Anvarifard et al.
The literature regarding the role of probiotics in critically ill patients who have undergone mechanical ventilation (MV) is unclear; therefore, this umbrella systematic review and meta-analysis was carried out to clarify the effects of pro...
The ameliorative mechanism of Lactiplantibacillus plantarum NJAU-01 against D-galactose induced oxidative stress: a hepatic proteomics and gut microbiota analysis [0.03%]
植物乳桿菌NJAU-01改善D-半乳糖致氧化應激的作用機制：基于肝臟蛋白組學和腸道微生物群分析
Du-Xin Jin,Chao-Yang Jia,Bo Yang et al.
Du-Xin Jin et al.
Probiotic intervention is an effective strategy to alleviate oxidative stress-related diseases. Our previous studies found that Lactiplantibacillus plantarum NJAU-01 (NJAU-01) exhibited antioxidant effects in a D-galactose (D-gal)-induced a...