Sinensetin, a polymethoxyflavone from citrus fruits, ameliorates LPS-induced acute lung injury by suppressing Txnip/NLRP3/Caspase-1/GSDMD signaling-mediated inflammatory responses and pyroptosis [0.03%]
柑橘类水果中的多甲氧基黄酮Sinensetin通过抑制TxnIP/NLRP3/ Caspase-1/GSDMD信号介导的炎症反应和细胞焦亡改善LPS诱导的大鼠急性肺损伤
Zaibin Xu,Huiyu Hu,Kongyan Wang et al.
Zaibin Xu et al.
Sinensetin (SIN), a polymethoxylated flavonoid, exists widely in citrus fruits with abundant biological activities, such as antioxidant and anti-inflammatory properties, delaying the progression of lung fibers and ameliorating inflammatory ...
Edible bird's nest regulates glucose and lipid metabolic disorders via the gut-liver axis in obese mice [0.03%]
鸟巢通过肠道-肝脏轴调节肥胖小鼠的糖脂代谢紊乱
Wei Zhang,Meizhen Zhu,Xuncai Liu et al.
Wei Zhang et al.
Edible bird's nest (EBN) is a traditional food known for its nourishing and functional properties and is found to be involved in anti-oxidation, anti-aging, and anti-influenza mechanisms, immune regulation, and improving cardiovascular dise...
Lower plasma linoleic acids as a risk factor for gout: an integrated analysis of population-based cohort and genetic data [0.03%]
血浆亚油酸水平较低是痛风的风险因素吗？基于人群队列和遗传数据的综合分析
Hao-Wei Tao,Zhong-Yue Liu,Wei Jiang et al.
Hao-Wei Tao et al.
Background: Gout is a nutrition-related, highly prevalent inflammatory arthritis with undesirable effects on the quality of life. The relationships between circulating fatty acids (FAs) and gout remain poorly understood. Method: We included...
Resistant starch and tannic acid synergistically ameliorated dextran sulfate sodium-induced ulcerative colitis, particularly in the distal colon [0.03%]
抗性淀粉和单宁酸协同改善葡聚糖硫酸钠诱导的溃疡性结肠炎，尤其是远端结肠的效果更好
Zijun Liu,Shunjing Luo,Chengmei Liu et al.
Zijun Liu et al.
We previously confirmed that tannic acid could delay the metabolism of resistant starch in vitro, which suggested that tannic acid might deliver resistant starch to the distal colon in vivo. Accordingly, co-supplementation of resistant star...
Underutilized Canadian wild berries as potential sources of lipophilic bioactive compounds with antihypertensive properties [0.03%]
加拿大未充分利用的野生浆果作为具有抗高血压性质的亲脂活性化合物的潜在来源
Chamali Kodikara,Thomas Netticadan,Sijo Joseph Thandapilly et al.
Chamali Kodikara et al.
Traditional berries are small fruits and are widely distributed in the Canadian prairies. The current study investigates the lipophilic bioactive compounds such as fatty acids, phytosterols, and terpenes, and their bioactivities, such as li...
In vitro fermentation reveals an interplay relationship between oat β-glucan and human gut Bacteroides and their potential role in regulating gut cytokines [0.03%]
体外发酵揭示燕麦β-葡聚糖与人体肠道细菌之间的相互作用关系及其潜在的调节肠道细胞因子的作用
Junying Bai,Jing Wang,Mingcong Fan et al.
Junying Bai et al.
Dietary oat β-glucan regulates the gut microbial composition and structure; however, the interplay relationship between oat β-glucan and the gut microbiota is unclear. In this study, we aim to investigate the interaction between oat β-gl...
Urolithin B protects mice from diet-induced obesity, insulin resistance, and intestinal inflammation by regulating gut microbiota composition [0.03%]
富布苷通过调节肠道菌群组成保护小鼠免受高脂饮食诱导的肥胖、胰岛素抵抗和肠炎
Peng Chen,Rong Wang,Jiexin Lei et al.
Peng Chen et al.
The increasing prevalence of obesity and type 2 diabetes (T2D) signifies the failure of conventional treatments for these diseases. The gut microbiota has been proposed as a key player in the pathophysiology of diet-induced T2D. Urolithin B...
Association between daily consumption of spicy food and bone mineral density in middle-aged and older adults: a cross-sectional study [0.03%]
经常食用辛辣食物与中老年人骨密度的关系：一项横断面研究
Wenhao Zhu,Haitao Zhang,Chunchun Yuan et al.
Wenhao Zhu et al.
Background: Many studies have reported the effects of spicy food on human health, but no studies have been conducted on the impact of long-term spicy food consumption on bone mineral density (BMD). This study aimed to investigate the impact...
Body mass index mediates the association between four dietary indices and phenotypic age acceleration in adults: a cross-sectional study [0.03%]
体重指数介导了四个饮食指数与成人表型衰老加速之间的关系：一项横断面研究
Jing Li,Zibo Wu,Sitong Xin et al.
Jing Li et al.
Background: Diet and body mass index (BMI) are widely recognized as being closely associated with aging. However, it remains unclear which dietary indices are associated with aging, and the extent to which BMI mediates the relationship betw...
Porphyra haitanensis glycoprotein regulates glucose homeostasis: targeting the liver [0.03%]
_porphyra haitanensis_ 蛋白质调节血糖平衡：作用于肝脏
Yujia Ou,Yuehong Guo,Haoyu Wang et al.
Yujia Ou et al.
In this study, we investigated the effects of glycoprotein (PG)-mediated regulation of Porphyra haitanensis on liver glucose metabolism in hyperglycemic mouse models, and sought to establish the underlying mechanism, as determined by the ch...