The effect of obesity and dietary soy protein with different isoflavone levels on fecal microbial composition in lean and obese Zucker rats over 9- and 18-week periods [0.03%]
肥胖及不同异黄酮水平的豆蛋白对leizucker和obzucker大鼠粪便微生物组成的影响：持续9周和18周的研究
Wei Li,Michael S Robeson nd,Christopher E Randolph et al.
Wei Li et al.
To characterize the effects of obesity and dietary soy protein with different isoflavone levels on fecal microbial composition, six-week-old male obese (fa/fa) Zucker rats were randomly assigned to receive a diet (6-7 rats per group) with p...
Natural polyphenol rutin inhibits ferroptosis in ulcerative colitis by regulating lipid metabolism via blocking the LCN2-ALOX15 axis [0.03%]
天然黄酮类化合物芸香苷通过阻断LCN2-ALOX15轴调节脂质代谢来抑制溃疡性结肠炎铁死亡作用研究
Yiming Sun,Guixuan Fang,Kangdi Liu et al.
Yiming Sun et al.
Ulcerative colitis (UC), a chronic inflammatory disorder with elevated carcinogenic risk, urgently requires multi-target therapeutic strategies. Ferroptosis, characterized by iron-dependent lipid peroxidation, emerges as a promising interve...
Fermented purple potato dough improves glycolipid metabolism by modulating gut microbiota and fecal metabolites in high-fat diet-induced obese mice [0.03%]
发酵紫色马铃薯面团通过调节肠道菌群和高脂饮食诱导的肥胖小鼠粪便代谢物来改善糖脂代谢
Yongli Zhang,Wenying Zeng,Xue Bai et al.
Yongli Zhang et al.
Obesity is one of the major global public health concerns. Purple potatoes exhibit anti-obesity properties attributable to their content of abundant polyphenols and amylose. However, the anti-obesity effects and underlying mechanisms of pur...
Propionate alleviates ulcerative colitis by modulating the PI3K/AKT signaling pathway and suppressing NLRP3 inflammasome activation [0.03%]
丙酸通过调节PI3K/AKT信号通路和抑制NLRP3炎性小体的活化来缓解溃疡性结肠炎
Yao Shi,Danqing Xin,Haojie Zhang et al.
Yao Shi et al.
Background: Ulcerative colitis (UC) poses a significant health challenge characterized by recurrent inflammation of the intestinal tract, yet effective treatment options remain elusive. While previous studies have hinted at the potential of...
Innovative fermented milk enriched with the safe probiotic Lactiplantibacillus plantarum LVS14: genomic characterization and in vivo effectiveness [0.03%]
一种新型的安全益生菌Lactiplantibacillus plantarum LVS14发酵乳：基因组表征及其体内功效
Nancy M El Halfawy,Samar M Aborhyem,Amel A Ibrahim
Nancy M El Halfawy
Lactiplantibacillus plantarum is a probiotic known for its diverse health-promoting effects. In the current study, fifty lactic acid bacteria isolates were screened for probiotic characteristics, cholesterol-reducing potential, antioxidant ...
Adherence to the EAT-Lancet reference diet and risk of type 2 diabetes, metabolic dysfunction-associated steatotic liver disease, and their co-occurrence [0.03%]
遵循EAT-Lancet参考饮食与2型糖尿病、代谢功能紊乱相关脂肪肝病及其共病风险的关系
Shunming Zhang,Xu-Fen Zeng,Yan Borné et al.
Shunming Zhang et al.
Background and aims: The EAT-Lancet Commission proposed a healthy dietary pattern to prevent diet-related diseases while promoting planetary sustainability, but little is known regarding its associations with type 2 diabetes (T2D) and metab...
Daily walnut consumption increases 6-sulfatoxymelatonin urinary levels and can improve sleep quality: a randomized crossover trial [0.03%]
每日食用核桃可以增加尿液6-硫酸水杨胺水平并且改善睡眠质量：一项交叉试验研究
María Fernanda Zerón-Rugerio,Aradeisy Ibarra-Picón,María Diez-Hernández et al.
María Fernanda Zerón-Rugerio et al.
We aimed to study the potential impact of daily consumption of walnuts on urinary 6-sulphatoxymelatonin (6-SMT) levels and sleep quality parameters. We conducted an open-label randomized crossover trial (NCT04799821) in 76 young adults (24....
Design, synthesis and evaluation of gluten peptide analogues as inhibitors of the HLA/DQ8-mediated celiac immune response [0.03%]
设计、合成和评价面筋肽类似物作为针对HLA-DQ8介导的乳糜泻免疫反应的抑制剂
Lucia Treppiccione,Vincenzo Mangini,Annarita Del Gatto et al.
Lucia Treppiccione et al.
The immune response induced by gluten is the result of molecular mechanisms involving gliadin peptides, DQ2 or DQ8 glycoproteins, and the interaction with T lymphocyte receptors. DQ8-glia-α1 is an immunodominant peptide present in gliadin ...
Egg matrices alleviate long-term florfenicol-induced behavioral alterations via the gut microbiota and host metabolism in mice [0.03%]
蛋黄矩阵通过肠道微生物群和宿主代谢缓解氟苯尼考引起的长期行为异常研究
Jie Bai,Yan Gong,Junlin Ge et al.
Jie Bai et al.
Florfenicol (FFC) is a broad-spectrum antibiotic that is commonly detected as a residue in livestock products, such as eggs. Although the adverse effects of FFC have been widely reported, the combined influence of the food matrix with FFC e...
Siraitia grosvenorii extract improves insulin tolerance and pancreatic islet function in ageing and HFD-induced diabetic mice [0.03%]
葫芦鲜味剂罗汉果提取物能改善衰老及高脂饮食致糖尿病小鼠的胰岛素耐受性和胰岛功能
Yan Gao,Chun-Cheng Pu,Ying Feng et al.
Yan Gao et al.
Siamenoside I (SI) is the sweetest compound isolated from Siraitia grosvenorii fruit. The extremely low natural abundance limits its application. We have previously produced an M3 extract (containing 68.5% SI) by subjecting Siraitia grosven...