Oral exposure to ovalbumin alters glucose metabolism in sensitized mice: upregulation of HIF-1α-mediated glycolysis [0.03%]
口服卵清蛋白暴露可改变过敏小鼠的糖代谢：HIF-1α介导的糖酵解的上调作用
Fangfang Min,Zhongliang Wang,Huming Shao et al.
Fangfang Min et al.
Food allergies are pathological adverse reactions against harmless dietary proteins. While studies have shown the involvement of host metabolic changes (e.g., lipid metabolism and amino acid metabolism) in the development of food allergy (F...
Astaxanthin promotes the longevity of Caenorhabditis elegans via modulation of the intracellular redox status and PHA-4-mediated autophagy [0.03%]
虾青素通过调节细胞内氧化还原状态和PHA-4介导的自噬促进秀丽隐杆线虫寿命延长
Feng Ding,Yan Zhao
Feng Ding
Astaxanthin is a xanthophyll carotenoid which has been associated with a number of health-promoting effects, including anti-aging; however, the underlying mechanisms are not fully understood. In the present study, it was found that astaxant...
The mediating role of C-reactive protein (CRP) in the dietary intake of flavonoids and the risk of albuminuria [0.03%]
饮食类黄酮摄入量与尿白蛋白之间的关系：C-反应蛋白的介导作用
Feng Jiang,Tiantian Zheng,Yong Jie Li
Feng Jiang
Background: Prior experimental investigations have highlighted the beneficial effects of flavonoid consumption on renal function. However, a comprehensive evaluation of their impact on modulating albuminuria risk within population-based epi...
Differential effects of EPA and DHA on aging-related sarcopenia in mice and possible mechanisms involved [0.03%]
EPA和DHA对小鼠衰老相关肌少症的差异性影响及可能机制
Zi-Jian Wu,Ying-Chao Li,Yan Zheng et al.
Zi-Jian Wu et al.
Sarcopenia frequently occurs with aging and leads to major adverse impacts in elderly individuals. The protective effects of omega-3 polyunsaturated fatty acids against aging-related sarcopenia have been demonstrated; however, the effect an...
Tetrahydrocurcumin alleviates di-(2-ethylhexyl) phthalate-induced adipose tissue dysfunction and testicular toxicity in adult mice: possible involvement of adiponectin-adipoR signaling in the testis [0.03%]
tetrahydrocurcumin缓解Di-(2-乙基己基)邻苯二甲酸对成年小鼠脂肪组织功能障碍和睾丸毒性的诱导：可能涉及睾丸中的脂联素-脂联素受体信号通路
Choirul Anwar,Yu-Chi Chu,Mei-Ling Tsai et al.
Choirul Anwar et al.
Widespread exposure to endocrine disruptors is associated with metabolic dysfunction and reproductive toxicity. Tetrahydrocurcumin (THC) has attracted attention as it offers protection against obesity and metabolic disorders due to its pote...
Screening of the effect of new food prototypes based on fermented lentil and quinoa flours on the colonic microbiota of older adults through a static in vitro colonic fermentation model [0.03%]
基于发酵鹰嘴豆和奇雅子面粉的新食品原型对老年人结肠微生物组影响的筛选研究：一种静态体外结肠发酵模型的方法学应用
Elena Gomez-Gomez,Andrea Asensio-Grau,Ana Heredia et al.
Elena Gomez-Gomez et al.
In view of the increasing demand for plant-based protein alternatives, along with the increased protein requirements of older adults, the formulation of new food concepts based on protein-rich ingredients from legumes or pseudo-cereals seem...
Pediococcus acidilactici Y01 reduces HFD-induced obesity via altering gut microbiota and metabolomic profiles and modulating adipose tissue macrophage M1/M2 polarization [0.03%]
枯草芽孢杆菌Y01通过改变肠道微生物组和代谢谱并调节肥胖组织中巨噬细胞的M1 / M2极化来减少HFD引起的肥胖症
Yujing Wang,Yu Xue,Huan Xu et al.
Yujing Wang et al.
Obesity-related metabolic syndrome is intimately associated with infiltrated adipose tissue macrophages (ATMs), gut microbiota, and metabolic disorders. Pediococcus acidilactici holds the potential to mitigate obesity; however, there exist ...
Anthocyanin-rich black wheat as a functional food for managing type 2 diabetes mellitus: a study on high fat diet-streptozotocin-induced diabetic rats [0.03%]
富含花青素的黑小麦作为管理二型糖尿病的功能性食品研究：高脂饮食-链脲佐菌素诱导的糖尿病大鼠模型研究
Vandita Tiwari,Akhil Kamboj,Bhawna Sheoran et al.
Vandita Tiwari et al.
Background: Type 2 Diabetes Mellitus (T2DM) is associated with insulin resistance, hyperglycemia, and hyperlipidemia. Anthocyanins, which are natural antioxidants, have been reported to manage T2DM-related complications. However, the potent...
Solanum lycopersicum derived exosome-like nanovesicles alleviate restenosis after vascular injury through the Keap1/Nrf2 pathway [0.03%]
源自Solanum lycopersicum的类似外体的纳米囊泡通过Keap1/Nrf2途径缓解血管损伤后的再狭窄
Hechen Shen,Meng Zhang,Dachang Liu et al.
Hechen Shen et al.
Despite the significant alleviation of clinical cardiovascular diseases through appropriate interventional treatments, the recurrence of vascular restenosis necessitating reoperation remains a substantial challenge impacting patient prognos...
Impact of astaxanthin on the capacity of gut microbiota to produce tryptophan catabolites [0.03%]
虾青素对肠道菌群生成色氨酸衍生代谢产物能力的影响
Pengfei Ren,Biqian Wei,Wanting Qin et al.
Pengfei Ren et al.
This study utilized in vitro colonic fermentation to examine the impact of astaxanthin on the microbial catabolism of tryptophan. Astaxanthin significantly altered the gut microbiota and raised the tryptophan catabolism metabolite levels in...