Dietary alpha-lipoic acid alleviates heat stress by modulating insulin-like signaling to maintain homeostasis in C. elegans [0.03%]
饮食α-硫辛酸通过调节类胰岛素信号维持线虫的体内平衡来缓解热应激
Longnong You,Zirui Huang,Wenyuan He et al.
Longnong You et al.
Prolonged exposure to high temperatures can cause oxidative stress in the body, negatively impacting human health. Alpha-lipoic acid (ALA) is a naturally occurring antioxidant prevalent in both plant and animal foods, exhibiting bioactivity...
Flaxseed-derived peptide, Ile-Pro-Pro-Phe (IPPF), ameliorates hepatic cholesterol metabolism to treat metabolic dysfunction-associated steatotic liver disease by promoting cholesterol conversion and excretion [0.03%]
来自亚麻籽的肽Ile-Pro-Pro-Phe (IPPF)通过促进胆固醇转化和排泄来改善肝胆固醇代谢，从而治疗与代谢功能障碍相关的脂肪性肝病
Xingyu Yuan,Yifeng Hou,Narisu Qin et al.
Xingyu Yuan et al.
Flaxseed-derived peptide IPPF has been reported to effectively inhibit cholesterol micellization and reduce cholesterol accumulation in vitro. However, its effects on hepatic cholesterol accumulation and related dysfunction-associated steat...
Comment on "The quercetin metabolite 4-methylcatechol causes vasodilation via voltage-gated potassium (Kv) channels" by Patrícia Dias, Rudy Salam, Jana Pourová, Marie Vopršalová, Lukáš Konečný, Eduard Jirkovský, Jurjen Duintjer Tebbens and Přemysl Mladěnka, Food & Function, 2024, 15, 11047 [0.03%]
对Patrícia Dias等人发表在《食品与功能》2024年第15期第11047页上的论文"The quercetin metabolite 4-methylcatechol causes vasodilation via voltage-gated potassium (Kv) channels"（黄酮醇代谢物4-甲基 catechol通过电压门控钾(Kv)通道引起血管舒张）的评论
Rían W Manville,Hanh A Nguyen,Geoffrey W Abbott
Rían W Manville
Voltage-gated potassium (Kv) channels in the Kv1 and Kv7 gene families are expressed in vascular smooth muscle, where they can modulate cellular excitability and potentially act as targets for antihypertensive drugs and botanicals. In an ar...
Effects of polyphenols on non-alcoholic fatty liver disease: a case study of resveratrol [0.03%]
多酚对非酒精性脂肪肝疾病的影响：白藜芦醇的病例研究
Ying Zhao,Jiali Ren,Weisan Chen et al.
Ying Zhao et al.
The primary etiology of liver disease is non-alcoholic fatty liver disease (NAFLD), which can progress to non-alcoholic steatohepatitis, cirrhosis, and ultimately hepatocellular carcinoma. The efficacy of plant-derived polyphenolic compound...
Polyphenol extracts from rambutan peel promote longevity via the attenuation of the Toll/Imd pathway [0.03%]
番荔枝果皮的多酚提取物通过衰减Toll/Imd通路促进长寿
Jian-Cong Huang,Xue-Kun Pan,Shun-Cai Li et al.
Jian-Cong Huang et al.
Rambutan peel is rich in polyphenols such as ellagic acid, corilagin, geraniin, quercetin, and rutin, which contribute to its diverse health benefits, including antioxidant, antimicrobial, antiviral, anti-inflammatory, hypoglycemic, and pot...
Ergosterol originated from Auricularia auricula attenuates high fat diet-induced obesity and cognitive impairment in mice [0.03%]
牛肝菌来源的麦角固醇减轻高脂饮食诱导的小鼠肥胖和认知障碍
Wei Song,Lina Zhu,Chunyan Yang et al.
Wei Song et al.
Excessive intake of a high fat diet (HFD) leads to accumulation of fat and obesity. Ergosterol (ERG) is a characteristic sterol of fungi with various bioactive functions; however, there are few studies on the ERG function of ameliorating ob...
Organic acids from ice wine ameliorate fructose-induced disorders of glycolipid metabolism in C57BL/6J mice [0.03%]
冰酒中的有机酸改善C57BL/6J小鼠由果糖导致的脂代谢和糖代谢紊乱性疾病
Yang Liu,Fuliang Han,Xinyuan Ma et al.
Yang Liu et al.
Excessive intake of fructose has been widely reported to cause glycolipid metabolism disorders, and it is unclear whether long-term consumption of ice wine, a sweet wine with high sugar content, is beneficial for health. In this study, 6-we...
Structural modification of lactoferrin by epigallocatechin gallate: elucidation of its structure and exploration of its potential in promoting osteoblast proliferation [0.03%]
表没食子儿茶素没食子酸酯对乳铁蛋白的结构修饰：明确其结构并探索其促进成骨细胞增殖的潜力
Zhenni Zhai,Xiaoni Lian,Fengjiao Fan et al.
Zhenni Zhai et al.
Lactoferrin (LF) and epigallocatechin gallate (EGCG) are recognized for their potent osteogenic properties. However, the osteogenic activity of LF-EGCG complexes is not fully understood. In this study, both non-covalent and covalent LF-EGCG...
New perspectives on the taste mechanisms of umami and bitter peptides in low-salt fermented fish sauce based on peptidomics, molecular docking and molecular dynamics [0.03%]
基于肽组学、分子对接和分子动力学的低盐发酵鱼露中鲜味和苦味肽的味觉机制新视角
Jiarun Han,Hangjia Zhang,Qi Wang et al.
Jiarun Han et al.
Umami and bitter peptides generated by microbial metabolism are essential to the taste of low-salt fish sauce. However, the uncertain taste mechanisms of peptides hinder the efficient identification of high-intensity taste peptides in fish ...
Insights from traditional fermented legumes towards the innovation of modern plant-based meat analogues [0.03%]
传统发酵豆制品对现代植物基肉制品创新的启示
Raisa Rudge,Reed A Nicholson,Colleen Cottrell et al.
Raisa Rudge et al.
There has been a major growth in the development of plant-based meat alternatives (PBMA) in recent years. However, current PBMA often contain ultra processed ingredients and numerous additives to be able to mimic animal-based meat (ABM) inc...