Pediococcus acidilactici KCTC 15831BP-fermented industrial hempseed (Cannabis sativa L.) supplementation corrects metabolite and gut microbiota dysbiosis, potentially mitigating Alzheimer's disease-like symptoms induced by obesity in high-fat diet-fed mice [0.03%]
植物乳桿菌KCTC 15831BP發酵的工業大麻籽（Cannabis sativa L.）補充劑可糾正代謝物和腸道微生物群的異常，可能消除高脂肪飲食小鼠肥胖引起的類似阿爾茨海默氏病的症狀
Simon Okomo Aloo,Ramachandran Chelliah,Fred Kwame Ofosu et al.
Simon Okomo Aloo et al.
A long-term high-fat diet (HFD) intake causes obesity, disrupting the gut microbiota and body metabolite balance, and increasing the risk of Alzheimer's disease (AD). Fermented hempseed may restore microbiota balance, improve metabolism, an...
Cinnamic acid ameliorates diabetic nephropathy in rats via Nrf2 activation and inflammation modulation [0.03%]
香豆酸通过激活Nrf2和调节炎症来改善糖尿病肾病
Setah Naif Alotaibi,Ghedeir M Alshammari,Nawal A Albadr et al.
Setah Naif Alotaibi et al.
This study investigates the therapeutic effects of cinnamic acid (CA) on diabetic nephropathy (DN) and elucidates its mechanisms involving Nrf2 activation and NF-κB suppression. Type 2 diabetes mellitus (T2DM) was induced in Wistar rats th...
Efficacy and safety of steamed ginger extract for gastric health: a randomized, double-blind, placebo-controlled multi-center clinical trial [0.03%]
蒸制生姜提取物对胃健康的功效及安全性：随机、双盲、安慰剂对照多中心临床试验
Hyang-Im Baek,Nu-Ri Ha,Chul Kim et al.
Hyang-Im Baek et al.
The aim of this study was to investigate the efficacy and safety of steamed ginger extract (GGE03) for mild to moderate functional dyspepsia (FD) in a 12-week randomized, double-blind, placebo-controlled clinical trial. A total of 80 subjec...
Diet, genetic factors, and the risk of gastroesophageal reflux disease, Barrett's esophagus and esophageal adenocarcinoma [0.03%]
饮食、遗传因素与胃食管反流病、巴雷特食管及食管腺癌风险的关系
Tongyu Zhang,Meiyou Lu,Zihan Li et al.
Tongyu Zhang et al.
Introduction: Diet has been recognized as the most pivotal modifiable lifestyle factor in the development of Gastroesophageal Reflux Disease (GERD), Barrett's Esophagus (BE) and Esophageal Adenocarcinoma (EA). However, the associations betw...
Weissella confusa WIKIM51 (Wilac D001) improves constipation and gut health in a loperamide-induced mouse model [0.03%]
魏斯氏菌属迷惑 strain WIKIM51（Wilac D001）改善洛哌丁胺诱导小鼠模型的便秘和肠道健康状况
Dan-Bi Ki,Jong-Yeon Kim,Varun Jaiswal et al.
Dan-Bi Ki et al.
Weissella confusa WIKIM51 (Wilac D001) has been reported to reduce body fat, but its potential effects on constipation remain unclear. This study is the first to demonstrate that Wilac D001 alleviates loperamide-induced constipation in vivo...
Anti-photoaging activity of cod peptides: structural characterisation and clinical validation [0.03%]
鱼胶原蛋白肽抗皮肤衰老功效及临床验证
Lijuan He,Ruijia Liu,Linfeng Chen et al.
Lijuan He et al.
The role of collagen peptides in anti-photoaging has attracted considerable research attention; however, the structure-activity relationship between their specific structural characteristics and biological efficacy remains poorly defined. I...
Whole grains are not equal: the role of fiber structure and phytochemicals in health [0.03%]
全谷物不平等：纤维结构和植物化学物质在健康中的作用
Salar Hafez-Ghoran,Fatemeh Taktaz,Shengmin Sang
Salar Hafez-Ghoran
Precision nutrition seeks to optimize human health by tailoring dietary interventions to individual genetic, metabolic, microbial, and lifestyle profiles. In this context, whole grains (WGs) serve as ideal candidates, as their diverse fiber...
Integrating population-based metabolomics with computational microbiome modelling identifies methanol as a urinary biomarker for protective diet-microbiome-host interactions [0.03%]
整合人群代谢组学与计算微生物组建模鉴定甲醛为保护性饮食-微生物组-宿主互作的尿液生物标志物
Kristin Klier,Ameneh Mehrjerd,Daniel Fässler et al.
Kristin Klier et al.
Background: Diet-microbiome interactions are core to human health, in particular through bacterial fibre degradation pathways. However, biomarkers reflective of these interactions are not well described. Methods: Using the population-based ...
Gut microbiota mediated the curvilinear association between dietary animal protein intake and bone mineral density in Chinese adults [0.03%]
膳食动物蛋白摄入对骨密度的U形关联与中国居民肠道菌群有关
Yan-Jun Deng,Qiong Zhang,Mao-Xin Ren et al.
Yan-Jun Deng et al.
Dietary protein intake is closely related to bone health. However, it remains unclear how different dietary protein sources contribute to bone mass and how the gut microbiota affects these processes. This study investigated the relationship...
Dietary hispidulin ameliorated chemically-induced colitis by inhibiting epithelial cell ferroptosis via the ACAT2-GPX4 axis and remodeling the gut microbiota [0.03%]
饮食中的hispidulin通过ACAT2-GPX4轴抑制上皮细胞铁死亡并重塑肠道微生物群来改善化学诱导的结肠炎
Dapeng Chen,Jiayi Li,Xinyu Li et al.
Dapeng Chen et al.
Hispidulin, a dietary flavonoid occurring naturally in brown algae, has attracted considerable interest owing to its functions in modulating inflammatory responses and neutralizing reactive oxygen species. This study examined the consequenc...