Lactic acid bacteria target NF-κB signaling to alleviate gastric inflammation [0.03%]
乳酸菌通过作用于NF-κB信号通路来缓解胃炎
Shiying Wu,Yuenuo Luo,Fangtong Wei et al.
Shiying Wu et al.
Helicobacter pylori (H. pylori) infection and the resulting gastric inflammation are major contributors to gastric cancer development. Probiotics, particularly Lactobacillus, are promising for their anti-inflammatory potential, yet their ex...
The role of cecal metabolites and DNA methylation in deciphering the effects of maternal genistein intake on white fat browning in adult female offspring [0.03%]
母体摄入的大豆异黄酮对后代白色脂肪棕色化的效应中盲肠代谢物和DNA甲基化的作用
Shunhua Li,Liyuan Zhou,Jing Ren et al.
Shunhua Li et al.
Maternal diets during pregnancy and lactation are critical determinants that regulate the metabolic homeostasis in offspring. Our previous research demonstrated that maternal genistein (GEN) intervention ameliorated the dysregulation of glu...
Native Brazilian fruits: postprandial glycemic control and carbohydrate-enzyme inhibition - insights from a randomized crossover clinical trial [0.03%]
巴西本地水果对餐后血糖控制和碳水化合物酶抑制的影响 - 随机交叉临床试验的见解
Isabella de Araújo Esteves Duarte,Thais Mie Ando de Mello Araújo,Layanne Nascimento Fraga et al.
Isabella de Araújo Esteves Duarte et al.
Brazilian native fruits are excellent sources of polyphenols, especially berries, which are rich in anthocyanins. These compounds are associated with improvements in the insulin signaling pathway, reduced glucose absorption, and the inhibit...
Lycopene improves cisplatin induced hepatointestinal injury in rats by modulating the microbe-gut-liver axis [0.03%]
番茄红素通过调节微生物-肠-肝轴改善大鼠顺铂诱导的肝肠损伤
Enshuang Xu,Zhiying Yu,Jiasan Zheng
Enshuang Xu
Cisplatin (CIS) is a commonly used antitumor drug in clinics, but its application is limited due to hepatotoxicity, nephrotoxicity and gastrointestinal toxicity. In recent years, a large number of studies have shown that the imbalance of in...
Bifidobacterium breve HH079 alleviates early-life antibiotic-exposed colon dysbiosis in mice by restoring the gut microbiota and gut barrier function [0.03%]
短双歧杆菌HH079通过恢复肠道微生物群和肠屏障功能来缓解小鼠早期生命抗生素暴露引起的结肠菌群失衡
Zhipeng Gu,Zerong Lu,Jian-Yong Wu et al.
Zhipeng Gu et al.
Antibiotic exposure in early life disrupts gut microbiota development in infants, which could result in intestinal dysfunction. This study mimicked early-life antibiotic exposure in mice by administering antibiotic water to lactating dams, ...
Cynarin protects against seizures and neuronal death in a rat model of kainic acid-induced seizures [0.03%]
cynarin可保护抗海人酸诱发的癫痫大鼠模型中的癫痫和神经元死亡
Cheng-Wei Lu,Tzu-Yu Lin,Wun-Jing Pan et al.
Cheng-Wei Lu et al.
The potential therapeutic value of cynarin, a phenolic compound derived from artichoke, in treating epilepsy has not yet been reported. The present study evaluated the effects of cynarin on a kainic acid (KA)-induced seizure rat model and i...
Comparative assessment of flavonoid content in banana pulp and peel and their role in mitigating bone loss conditions and promoting osteoblast differentiation [0.03%]
香蕉果肉和果皮中黄酮含量的比较评估及其对缓解骨质流失状况和促进成骨细胞分化的功效研究
Shradha Sinha,Anirban Sardar,Divya Rai et al.
Shradha Sinha et al.
Banana fruit is widely grown and serves as a source of income across the tropics. It is known for its nutritional qualities and well-recognized medicinal applications. Given that banana pulp and peel are rich in flavonoids, such as naringen...
Bioactive peptides from barley protein hydrolysate stimulate cholecystokinin secretion via calcium-sensing receptor signaling in enteroendocrine cells [0.03%]
来自大麦蛋白水解物的生物活性肽通过肠道内分泌细胞中的钙敏受体信号途径促进胆囊收缩素分泌
Hongdong Song,Lei Xue,Zhuwei Shao et al.
Hongdong Song et al.
Anorexigenic hormone cholecystokinin (CCK), secreted by enteroendocrine cells (EECs), is known for its inhibitory role in appetite. The secretion of CCK is greatly affected by dietary ingredients. The search for functional components in foo...
Potential of queen bee larvae as a dietary supplement for obesity management: modulating the gut microbiota and promoting liver lipid metabolism [0.03%]
王浆幼虫作为减肥膳食补充剂的潜能：调节肠道微生物和促进肝脏脂质代谢
Zhuang Li,Yiang Chen,Tengfei Shi et al.
Zhuang Li et al.
Queen bee larvae (QBL) have been consumed as both a traditional food and medicine in China for thousands of years; however, their specific benefits for human health, particularly their potential anti-obesity property, remain underexplored. ...
Phlorizin mitigates high glucose-induced metabolic disorders through the IIS pathway in Caenorhabditis elegans [0.03%]
phlorizin通过Caenorhabditis elegans中的IIS通路减轻高葡萄糖诱导的代谢紊乱
Qi Gu,Chenlu Wang,Han Huang et al.
Qi Gu et al.
Phlorizin is a dihydrochalcone with various biological activities. To elucidate the mechanism of mitigating high glucose-induced metabolic disorders by phlorizin, the integrated approach combining metabolomics and gene expression profiling ...