Effect of pectinase addition in juice processing on the structural characteristics, immunological activity and in vitro and in vivo prebiotic properties of apple pomace pectic polysaccharides [0.03%]
果胶酶对苹果皮渣果胶多糖结构特性、免疫活性及体内外益生理功能的影响
Fangfang Yue,Miao Jiang,Jiaxin Xu et al.
Fangfang Yue et al.
Apple pomace is a waste in fruit juice processing and is an important raw material for pectin extraction. The addition of pectinase will not only change the juice characteristics but also affect the apple pomace. However, the differences in...
Crocin extends lifespan by mitigating oxidative stress and regulating lipid metabolism through the DAF-16/FOXO pathway [0.03%]
通过DAF-16/FOXO途径减轻氧化应激和调节脂质代谢从而延长寿命：一项关于crocin作用机制的研究
Ai-Pei Li,Dan Li,Xin Tan et al.
Ai-Pei Li et al.
Aging represents a significant global challenge characterized by persistent oxidative stress and dysregulated lipid metabolism. Crocin, the primary bioactive constituent of saffron (Crocus sativus L.), is widely utilized as a natural food c...
Metabolomics-based analysis of the effects of differences in soluble sugars on the sweetness quality of six major tea types in China [0.03%]
基于代谢组学分析六大茶类可溶性糖差异及其对鲜爽型风味的影响效应
Wen Li,Zhenbiao Zhang,Ruohong Chen et al.
Wen Li et al.
Soluble sugars are indeed key factors in the formation of tea sweetness quality. However, the specific impact they exert on tea sweetness has not been clearly elucidated. Consequently, in this study, one bud and two leaves of the same tea v...
The polyphenol/caffeine ratio determines the arousal-inducing properties of the green tea ethanol extract [0.03%]
原儿茶素/咖啡因比例决定了绿茶乙醇提取物的兴奋作用性质
Duhyeon Kim,Seonghui Kim,Gibeom Choi et al.
Duhyeon Kim et al.
Green tea (Camellia sinensis L.), one of the most popular beverages worldwide, contains caffeine, a natural stimulant. However, some green tea extracts have been known to possess both hypnotic and arousal effects. This study aimed to identi...
Curcumin exerts anti-tumor activity in colorectal cancer via gut microbiota-mediated CD8+ T Cell tumor infiltration and ferroptosis [0.03%]
姜黄素通过肠道菌群介导的CD8⁺T细胞肿瘤浸润和铁死亡在结直肠癌中发挥抗肿瘤作用
Hongli Zhou,Yupei Zhuang,Yuwei Liang et al.
Hongli Zhou et al.
Colorectal cancer (CRC), as a high-incidence malignancy, continues to present significant challenges in prevention, screening, and treatment. Curcumin (Cur) exhibits notable anti-inflammatory and anticancer properties. Despite its poor solu...
The unexpected role of B vitamins in osteoarthritis: a call for caution [0.03%]
维生素B在骨关节炎中的意外作用：谨慎行事的呼吁
Jingkai Di,Liying Song,Lujia Liu et al.
Jingkai Di et al.
Background: The purpose of this study was to investigate the single and mixed effects of B vitamins on OA. Methods: Data from the National Health and Nutrition Examination Survey (NHANES) database, from 2003 to 2018, were extracted. A weigh...
Hepatoprotective effects of wine-steamed Schisandra sphenanthera fruit in alleviating APAP-induced liver injury via the gut-liver axis [0.03%]
五味子果实葡萄酒蒸制产物通过肠肝轴改善对乙酰氨基酚致小鼠急性肝损伤的机制研究
Xiaorui Wang,Xilin Fang,Jia Zhou et al.
Xiaorui Wang et al.
Drug-induced liver injury (DILI) is a common adverse drug reaction that can result in liver injury, particularly in cases of paracetamol (APAP) abuse. Schisandra sphenanthera Rehd. et Wils. has attracted attention due to its hepatoprotectiv...
Probiotics improve lung function and QOL in participants with exposure to fine particulate matter air pollution: a randomized, double-blind, placebo-controlled clinical trial [0.03%]
益生菌改善细颗粒物空气污染暴露者的肺功能和生活质量：随机、双盲、安慰剂对照临床试验
Yongcan Wu,Caixia Pei,Xiaomin Wang et al.
Yongcan Wu et al.
Background: Probiotics have been reported to alleviate pulmonary inflammation through the gut-lung axis. However, their effects on PM2.5-induced toxic reactions have not yet been well studied. Objective: This study aims to investigate the e...
Impact of maternal Lactiplantibacillus plantarum S58 supplementation on offspring rat immunity and gut health [0.03%]
母体植物乳杆菌S58补充对子代大鼠免疫和肠道健康的影响
Yu-Ting Zhao,Yu-Hang Jiang,Xi Zhang et al.
Yu-Ting Zhao et al.
Pregnancy and lactation provide several opportunities for maternal dietary interventions to confer health benefits to newborns. However, the effects of maternal probiotic supplementation during pregnancy and lactation on offspring immunity ...
Preventive effects of turmeric against HFD/STZ-induced type 2 diabetes in mice by activating IRS1/PI3K/Akt signaling in association with gut microbiota metabolism [0.03%]
姜黄通过激活IRS1 / PI3K / Akt信号与肠道微生物群代谢相关联预防HFD / STZ诱导的2型糖尿病小鼠的作用
Chengcheng Yang,Yao Du,Lusha Wei et al.
Chengcheng Yang et al.
This study is the first to investigate the antidiabetic effect of turmeric powder (TP) and its underlying molecular mechanism in type 2 diabetes mellitus (T2DM) mice. The T2DM mice were supplemented with or without TP (8%) for 8 weeks. The ...