Exploring the lipid-lowering effects of cinnamic acid and cinnamaldehyde from the perspective of the gut microbiota and metabolites [0.03%]
肉桂酸和肉桂醛降脂作用的肠道菌群及代谢物视角研究
Xueke Wang,Tianxing Li,Ling Dong et al.
Xueke Wang et al.
The increasing incidence and associated metabolic complications pose major challenges in the treatment of hyperlipidaemia. Cinnamon is a food and medicinal resource associated with lipid metabolism, but the mechanism by which its active com...
The natural dihydrochalcone phloretin reduces lipid accumulation via downregulation of IIS and sbp-1/ SREBP pathways in HepG2 cells and Caenorhabditis elegans [0.03%]
天然二氢查耳酮花青素通过下调胰岛素信号通路和sbp-1/SREBP通路减少HepG2细胞和秀丽杆线虫的脂质堆积
Qi Gu,Litao Wang,Mingyue Xu et al.
Qi Gu et al.
Phloretin, a natural dihydrochalcone, exhibits significant potential in modulating lipid metabolism both in vitro and in vivo. This study investigated the effects of phloretin on lipid accumulation in HepG2 cells and Caenorhabditis elegans....
Fruits native to South America: a narrative review of their biological properties and chemical profiles [0.03%]
南美洲本土水果的功能特性及化学组成叙事性综述研究
Ana Sofia Martelli Chaib Saliba,Pedro Luiz Rosalen,Marcelo Franchin et al.
Ana Sofia Martelli Chaib Saliba et al.
Fruits native to South America have been recognized for their relevant levels of phytochemicals with bioactivities that offer human health benefits beyond nutrition; however, many of them remain unexplored. The objective of this study was t...
Multi-omics analysis reveals the attenuation effect of C-phycocyanin on aging-induced subfertility in female mice [0.03%]
多组学分析揭示了藻蓝蛋白缓解衰老诱导的小鼠不孕症状的作用机制
Zhe Han,Xin Wen,Lei Ge et al.
Zhe Han et al.
Excessive inflammatory responses within the ovary are one of the main causes of subfertility in elderly women. Eliminating these responses can reverse fertility in aged individuals. Here, we demonstrate that administering 300 mg kg-1 day-1 ...
Association between the quality of plant-based diets and risk of thyroid dysfunction [0.03%]
基于植物的饮食质量与甲状腺功能障碍风险之间的关系
Juanjuan Zhang,Yuchuan He,Zhiyuan Tang et al.
Juanjuan Zhang et al.
Background: Plant-based diets are generally considered to be associated with a decreased risk of several chronic diseases. However, there is limited prospective evidence on the association between plant-based diet quality and thyroid dysfun...
Food microstructure and protein digestion in the human gastrointestinal tract: an ileostomy study focusing on interindividual variability in gluten digestibility [0.03%]
人胃肠道中食物微观结构与蛋白消化：以回肠造口术关注 Gluten 消化性的个体差异性研究
Daniela Freitas,Joan Colom,Laura G Gómez-Mascaraque et al.
Daniela Freitas et al.
The degree of digestion of gluten proteins is thought to be directly linked to their capacity to elicit immune-mediated responses in predisposed individuals. Levels and timing of detection of gluten epitopes in stool samples exhibit high in...
Oat beta-glucans consumed at breakfast improve glucose tolerance acutely and after a subsequent lunch - a randomized dose-response study in healthy young adults [0.03%]
燕麦β-葡聚糖早餐摄入可改善血糖耐量并降低午餐后的血糖水平——健康年轻人中的随机剂量反应研究
Mohammad Mukul Hossain,Juscelino Tovar,Lieselotte Cloetens et al.
Mohammad Mukul Hossain et al.
Oat beta-glucans (OBGs) lower postprandial blood glucose by increasing gastrointestinal viscosity, delaying gastric emptying, and slowing glucose absorption. While the European Food Safety Authority (EFSA) recommends a minimum intake of 4 g...
Inhibitory mechanism study of soyasaponins on thrombin: extraction, purification, and functional property analysis [0.03%]
大豆皂苷的抗凝血作用机制研究：提取、纯化及功能性质分析
Mengqian Chen,Pengcheng Wang,You Li et al.
Mengqian Chen et al.
This study aimed to investigate the inhibitory effects of soyasaponins extracted from soybean meal on thrombin, thereby providing scientific evidence for the application of soybean meal byproducts in functional foods and cardiovascular dise...
Synergistic effect of 2'-fucosyllactose and osteopontin on intestinal mucosal immunity injury [0.03%]
2'-岩藻糖基乳糖与骨桥蛋白对肠道黏膜免疫损伤的协同作用
Rui Zhang,Sufang Duan,Xinming Ma et al.
Rui Zhang et al.
Previous studies have demonstrated the beneficial effects of 2'-fucosyllactose (2'-FL) and osteopontin (OPN) in modulating intestinal mucosal immunity. Nevertheless, the potential synergistic interactions and underlying mechanisms of 2'-FL ...
Proteome evaluation of the biological activity of grape seed extract (GSE) on the intestine of rats [0.03%]
葡萄籽提取物(GSE)对大鼠肠道生物活性的蛋白质组评价
Eduardo Guisantes-Batán,Sara Artigas-Jerónimo,Lorena Mazuecos et al.
Eduardo Guisantes-Batán et al.
Grape seed extract (GSE) is rich in polyphenols and has garnered attention for its potential health benefits, particularly in the gastrointestinal system. This study explores the principal effects of consuming a low dose of GSE on the intes...