Allicin induced vasorelaxation via endothelium-dependent and endothelium-independent mechanisms [0.03%]
大蒜素通过内皮依赖性和非依赖性机制引起血管舒张
Lei Tian,Su Zhao,Fenghua Ding et al.
Lei Tian et al.
Allicin is an active component of garlic that exerts protective effects against cardiovascular diseases. Vascular contraction and relaxation are the essential capacities of the vascular system to maintain its normal function. Endothelial ce...
Effects of astaxanthin on the mechanisms involved in skeletal muscle lipid metabolism and oxidative stress in an experimental model of metabolic syndrome [0.03%]
虾青素通过改善代谢综合征模型骨骼肌氧化应激及脂质代谢作用研究
María Eugenia Oliva,Valentina Degrave,Paola Ingaramo et al.
María Eugenia Oliva et al.
This study aimed to evaluate the mechanisms involved in skeletal muscle lipotoxicity, impaired lipid metabolism, and oxidative stress induced by a sucrose-rich diet (SRD) that mimics human Metabolic Syndrome (MS), and to assess the preventi...
Reshaping the gut microbiota to ameliorate DSS-induced colitis using a novel synbiotic consisting of jujube powder and Faecalibacterium prausnitzii [0.03%]
利用构杞粉和Faecalibacterium prausnitzii构建的新型合生元缓解DSS诱导结肠炎及重塑肠道菌群结构
Yalin Zhou,Zhenghuan Yang,Huiren Zhuang et al.
Yalin Zhou et al.
Ulcerative colitis (UC) remains challenging to existing therapeutic approaches, which may have variable efficacy, side effects, and high relapse rates. Increasing evidence indicates the critical role of the gut microbiota in UC pathogenesis...
Daily consumption of polyphenol-rich grape powder improves muscle strength markers in postmenopausal women [0.03%]
富含多酚的葡萄粉的每日摄入可改善绝经后妇女肌肉力量指标
Julianna L Mendez,Cecilia Rodriguez Lanzi,Zhikuan Quan et al.
Julianna L Mendez et al.
Sarcopenia is a debilitating age-associated condition with no effective treatment options. Therefore, there is high interest in evaluating whether food components, such as polyphenols found in grapes, could mitigate sarcopenia. However, the...
Daidzein alleviates CCl4- and BDL-induced liver fibrosis via suppressing the integrin alphaVbeta1/YAP signaling [0.03%]
大豆苷元通过抑制整合素alphaVbeta1/YAP信号缓解四氯化碳和胆管结扎诱导的肝纤维化
Junjie Bai,Zhongqiu Yang,Pengru Wang et al.
Junjie Bai et al.
Liver fibrosis is a pathological process characterized by the excessive deposition of diffuse extracellular matrix in the liver, serving as a reparative response of the body to chronic liver injury. Daidzein (DAI) is an isoflavone compound ...
Enhancing cognitive memory function with kumquat (Fortunella japonica Swingle) polyphenol extract: mechanisms of action in D-galactose-induced aging model mice [0.03%]
以福橘多酚提取物改善认知记忆功能：D-半乳糖致衰老模型小鼠的作用机制研究
Fuhua Li,Yingru Yi,Jichun Zhao et al.
Fuhua Li et al.
Kumquat polyphenols, known for their antioxidant, anti-inflammatory, have been less studied for their potential to delay aging and enhance cognitive memory. This research involved extracting and analyzing free and bound phenols from oil-ski...
Qian Zhao,Ancha Baranova,Fuquan Zhang
Qian Zhao
Alterations in calcium homeostasis are critical for the development of type 2 diabetes (T2D), but its specific impacts on this disease are unclear. We aimed to evaluate whether the potential effect is causal. In a two-sample Mendelian rando...
The effect of crocetin (a saffron carotenoid) supplementation on antioxidant and inflammatory indexes and serum leptin concentration in patients with coronary artery disease [0.03%]
藏红花类胡萝卜素番茄红素补充对冠心病患者抗氧化及炎症指标和血清瘦素浓度的影响
Faezeh Moeini Badi,S Zahra Bathaie,Fatemeh Borazjani et al.
Faezeh Moeini Badi et al.
Background: Coronary artery disease (CAD) is a common heart disease characterized by plaque buildup in the coronary arteries. Saffron, which is rich in active compounds, has strong antioxidant properties that help reduce free radicals and p...
6-Shogaol inhibits the cell motility of prostate cancer cells by suppressing the PI3K/AKT/mTOR and Ras/Raf/MAPK pathways with comparable effects to paclitaxel treatment [0.03%]
6-姜酚通过抑制PI3K/Akt/mTOR和Ras/Raf/MAPK途径抑制前列腺癌细胞迁移的作用与紫杉醇相当
Pei-Jhen Cai,Sheng-Yi Chen,Yi-Fan Chen et al.
Pei-Jhen Cai et al.
Prostate cancer ranks among the top causes of cancer-related deaths in men, with a substantial number of fatalities occurring in metastatic cases. Although paclitaxel (PTX) is used as a first-line treatment, its effectiveness is hindered by...
INFOGEST in vitro digestion: protein breakdown in relation to food composition and moisture content [0.03%]
体外消化法测定蛋白质水解与食物组成和含水量的关系
Alessandra Ferrara,Karen Mariel Treviño,Giovanni D&#x;Auria et al.
Alessandra Ferrara et al.
Driven by environmental sustainability, the transition to alternative food proteins is introducing a variety of plant-based products that simulate animal-derived foods. This study investigated the in vitro protein digestibility of a blend o...