A biotin-free diet attenuates the incidence of collagen-induced arthritis and alleviates microbial dysbiosis [0.03%]
无生物素饮食可降低自身免疫性关节炎发病率并缓解微生物群紊乱状况
Xiuli Su,Xiaona Li,Xiaojuan He et al.
Xiuli Su et al.
Emerging evidence has shown that the gut microbiota and its products are important triggers in the pathogenesis of rheumatoid arthritis (RA). Biotin is a diet- and microbiome-dependent metabolite and an immune regulator; however, the role o...
Ferulic acid identification in brown rice using untargeted metabolomics and network analysis and its effects in mitigating AFB1-induced hepatic damage [0.03%]
基于非目标代谢组学和网络分析的稻糠中富肺酸的鉴定及其对黄曲霉毒素B1诱导肝损伤的影响研究
Qianqian Wang,Gaigai Wang,Yanan Wang et al.
Qianqian Wang et al.
Regular consumption of brown rice has been linked to a reduction in the probability of oxidative stress-related diseases, including diabetes, Alzheimer's disease and cancer. The higher abundance of bioactive metabolites, including polypheno...
Effects of honey and Taiwanese green propolis on oral mucositis and quality of life in head and neck cancer patients undergoing radiotherapy: a randomized controlled trial [0.03%]
蜂蜜和台湾绿茶 propolis 对放射治疗头颈部癌症患者的口腔黏膜炎及生活质量的影响：随机对照试验
Shao-Ching Jen,Yue-Wen Chen,Jo-Ting Tsai et al.
Shao-Ching Jen et al.
Background: Head and neck cancer (HNC) significantly impacts patients' quality of life (QoL), particularly due to complications like oral mucositis (OM). This study evaluated the effectiveness of honey and Taiwanese green propolis (TGP) in ...
Lactobacillus acidophilus KLDS1.0901 ameliorates non-alcoholic fatty liver disease by modulating the tryptophan metabolite indole-3-aldehyde and acting on its receptor AhR [0.03%]
嗜酸乳杆菌KLDS1.0901通过调节色氨酸代谢物吲哚-3-甲醛及其受体AhR的作用改善非酒精性脂肪肝病
Zhengtao Guo,Shengjun Yang,Liwen Qi et al.
Zhengtao Guo et al.
Our previous study demonstrated that Lactobacillus acidophilus KLDS1.0901 significantly alleviated symptoms of high-fat diet (HFD)-induced non-alcoholic fatty liver disease (NAFLD) and showed a strong association with the gut microbiota; ho...
Exploring causal links in the gut-brain axis: a Mendelian randomization study of gut microbiota, metabolites, and cognition [0.03%]
探索肠道微生物组、代谢物和认知之间因果联系的孟德尔随机化研究
Sunan Gao,Angela Y Xiao,Siyu Zou et al.
Sunan Gao et al.
The causal mediation effects of metabolites between gut microbiota and cognitive phenotypes remain unclear. Guided by the gut-brain axis mechanism, this study employed systematic Mendelian randomization (MR) to investigate these mediation p...
Exploring tarhana's prebiotic potential using different flours in an in vitro fermentation model [0.03%]
采用不同面粉在体外发酵模型中探索tarhana的益生潜力
Fatma Koc,Merve Sabuncu,Günnur Gülkun Yavuz et al.
Fatma Koc et al.
Tarhana, a traditional fermented food important to Turkish and Central Asian cuisines, is known for its unique composition of yoghurt, flour, vegetables, and herbs, and its potential health benefits through fermentation. The aim of this stu...
Dietary methionine restriction ameliorates atherosclerosis by remodeling the gut microbiota in apolipoprotein E-knockout mice [0.03%]
甲硫氨酸限制通过重塑肠道菌群改善 apoE 缺失小鼠动脉粥样硬化病情
Hao Yang,Yuhui Yang,Guifang Cui et al.
Hao Yang et al.
Dietary methionine restriction (MR) has been shown to reduce the risk of atherosclerosis, but the specific regulatory effects and mechanisms remain unclear. This research intends to investigate the effects of MR on atherosclerosis in apolip...
Ketogenic diet attenuates microglia-mediated neuroinflammation by inhibiting NLRP3 inflammasome activation via HDAC3 inhibition to activate mitophagy in experimental autoimmune encephalomyelitis [0.03%]
生酮饮食通过抑制HDAC3激活自噬来抑制NLRP3炎性小体的活化，从而减轻自身免疫性脑脊髓炎中微胶质介导的神经炎症作用
Qianye Zhang,Mingxiao Zheng,Wei Sun et al.
Qianye Zhang et al.
The activation of microglia is an important cause of central nervous system (CNS) inflammatory cell infiltration and inflammatory demyelination in multiple sclerosis (MS). NOD-, LRR- and pyrin domain-containing protein 3 (NLRP3) inflammasom...
Neuroprotective effect of folic acid by maintaining DNA stability and mitochondrial homeostasis through the ATM/CHK2/P53/PGC-1α pathway in alcohol-exposed mice [0.03%]
叶酸通过ATM/CHK2/P53/PGC-1α通路维持DNA稳定性和线粒体稳态的神经保护作用：酒精暴露小鼠模型研究
Nan Zhang,Huaqi Zhang,Xi Liang et al.
Nan Zhang et al.
Excessive drinking leads to alcoholic brain injury, which is characterized by neuroinflammation, cognitive decline and motor dysfunction. These pathological features are closely related to chromosomal DNA damage and mitochondrial dysfunctio...
Temple stay diet and its impact on gut microbiome and irritable bowel syndrome: a prospective cohort study [0.03%]
韩国寺庙饮食对其肠道菌群和肠易激综合征的影响：队列研究
Sang Hoon Kim,Woorim Kang,Minyoung Kim et al.
Sang Hoon Kim et al.
Background/Aims: Irritable Bowel Syndrome (IBS) significantly impacts quality of life, with effective treatment challenged by its multifactorial pathogenesis. A temple stay program incorporating a vegetarian diet may benefit IBS by modulati...