Attenuation of colitis-related metabolic dysregulation via consumption of wholemeal sourdough bread but not wholemeal bread: a molecular discovery [0.03%]
通过摄入全麦酸面包而非全麦面包来缓解结肠炎相关的代谢紊乱：分子发现
Cheng Chen,Gaoheng Li,Anqi Wang et al.
Cheng Chen et al.
Epidemiological studies reveal that the majority of adult patients with inflammatory bowel disease (IBD) are obese and/or overweight. Whole wheat sourdough produced by lactic acid bacterial (LAB) fermentation can provide numerous benefits. ...
Exploring Galician phenolic-rich olive oil as a glycemic control strategy: the OILDIABET randomized trial [0.03%]
富含酚的加利西亚橄榄油降糖作用研究——OILDIABET随机对照试验
María Figueiredo-González,Inés Seoane-Cruz,Patricia Reboredo-Rodríguez et al.
María Figueiredo-González et al.
The rising prevalence of type 2 diabetes (T2D) demands effective dietary strategies. High-phenolic extra virgin olive oil (EVOO) has been proposed as a functional food with antidiabetic properties. This study evaluates the effects of a high...
Development of a bio-functional fermented soy beverage supplemented with microbial exopolysaccharides and its effect on the human gut microbiome in vitro [0.03%]
一种富含微生物胞外多糖的发酵豆奶饮料的开发及其对体外人肠道菌群的影响
Giulia Bisson,Clara Comuzzi,Jamie A FitzGerald et al.
Giulia Bisson et al.
The gut microbiome plays a key role in modulating human health and well-being. Exopolysaccharides (EPS) produced by lactic acid bacteria (LAB) are emerging as novel polymers that could exert a prebiotic effect via modification of this micro...
Screening of Lactococcus lactis strains with hypoglycemic effects and evaluation of their protective mechanisms against glucose-induced type 2 diabetes in zebrafish [0.03%]
低血糖作用乳酸菌筛选及其降糖保护机制的斑马鱼模型评价研究
Huiying Li,Huijing Chen,Jianquan Kan et al.
Huiying Li et al.
Type 2 diabetes mellitus (T2DM) is a major global health challenge, and probiotics represent a potential therapeutic avenue. In this study, three strains of probiotics with α-glucosidase inhibitory activity were screened in vitro, and the ...
Is moderate beer consumption associated with poor dietary and biochemical parameters of nutritional status in adults? A systematic review of observational and interventional studies with meta-analysis [0.03%]
适量饮酒与成人不良的饮食和生化营养参数有关吗？一项观察性和干预性研究的系统评价及荟萃分析
Liliana G González-Rodríguez,Iván Cavero-Redondo,Ana M López-Sobaler et al.
Liliana G González-Rodríguez et al.
The impact of heavy alcohol consumption on health and nutritional status is well-documented, but the effects of moderate beer consumption remain less well understood. This systematic review and meta-analysis examined evidence on moderate be...
Impact of extensively hydrolyzed infant formula on the probiotic and postbiotic properties of Lactobacillus fermentum in an in vitro co-culture model [0.03%]
一种水解婴儿配方奶粉对乳酸菌发酵子和其后生物因子在体外共培养模型中的影响研究
Marta Arroyo-Calatayud,Elisabeth M Haberl,Laura Olivares et al.
Marta Arroyo-Calatayud et al.
Early gut homeostasis is a balance between dietary antigen exposure, gut barrier function, microbiome establishment and orchestration of innate and adaptive immune responses. Imbalances during this early time of development can lead to incr...
A dietary switch from a high fat to a low fat diet mitigates obesity-induced intestinal barrier dysfunction in mice: implications for pancreatic carcinogenesis [0.03%]
高脂饮食向低脂饮食的转换可缓解肥胖引起的肠屏障功能障碍：对胰腺癌发生的意义
Jazmin Machuca,Joanna Wirkus,Aya S Ead et al.
Jazmin Machuca et al.
Consumption of high-fat diets (HFD) is linked to increased intestinal permeability and metabolic endotoxemia, which may contribute to pancreatic cancer development. We previously showed that 8-week HFD consumption altered intestinal barrier...
A casein-derived peptide exerted immunomodulatory effects by targeting protein phosphatase 1-catalytic subunit alpha: a potential alternative to combat infections [0.03%]
一种衍生自酪蛋白的肽通过靶向蛋白磷酸酶1调节亚单位α发挥免疫调节作用：对抗感染的新潜力
Jinyang Cai,Shanshan Wang,Lamei Wu et al.
Jinyang Cai et al.
Antibiotic resistance is a growing global threat to the effective treatment of bacterial infections, therefore, novel therapeutic alternatives need to be developed urgently. We recently reported that BCCY-1, a peptide derived from human β-...
Phytosterol-mediated disturbance of the lipid packing order in the plasma membrane regulates inflammatory response [0.03%]
植物固醇通过干扰质膜脂序来调控炎症反应
Xiuxiu Wang,Ya Liu,Fangling Du et al.
Xiuxiu Wang et al.
While phytosterols have been widely reported for their anti-inflammatory effects, the precise biophysical mechanisms underlying their regulation of inflammatory responses remain largely unexplored. Our study demonstrates that phytosterols e...
Vitamin K2 reprograms the multi-organ transcriptional landscape in mice with high-fat diet-induced obesity [0.03%]
维生素K2重新编程高脂饮食诱导的肥胖小鼠多器官转录景观
Xuanyang Wang,Yuntao Zhang,Lin Liu et al.
Xuanyang Wang et al.
Vitamin K2 (VK2) shows promise as a nutritional intervention for obesity-related disorders, but its mechanisms of action in obesity and associated phenotypes are not yet fully understood. This study aims to elucidate the rescue effects of V...