Hilde Ten Berge,Greta Piazza,Dianne Ramaker et al.
Hilde Ten Berge et al.
Aim: This study aimed to assess the cost-effectiveness of the annual volumetric-enabled low-dose computed tomography (LDCT) lung cancer screening (LCS), based on the NELSON screening outcomes, versus no screening for the asymptomatic high-r...
A disease progression model comparing the long-term mobility and respiratory outcomes of adults with late-onset Pompe disease receiving cipaglucosidase alfa plus miglustat versus alglucosidase alfa [0.03%]
α-半乳糖苷酶alfa与cipaglucosidase αfa加miglustat相比，成人晚发型庞贝病长期运动和呼吸结局的疾病进展模型比较
Amy Dymond,Will Green,Matthew Crabtree et al.
Amy Dymond et al.
Aim: Late-onset Pompe disease (LOPD) is a rare lysosomal disease primarily impacting muscle strength and respiratory function. LOPD has a substantial burden despite the availability of alglucosidase alfa (alg). Patients often require mobili...
R WE ready for reimbursement? A round-up of developments in real-world evidence relating to health technology assessment: part 27 [0.03%]
我们准备好报销了吗？有关基于现实世界证据的卫生技术评估最新进展的回顾（二十七）
Paul Arora,Sreeram V Ramagopalan
Paul Arora
In this update, we review the US FDA's updated compendium of real-world evidence (RWE) use in medical device regulatory decisions, a comprehensive scan of RWE utilization in Canadian drug reimbursement submissions, and Institute for Clinica...
Access in all areas? A round-up of developments in market access and health technology assessment: part 15 [0.03%]
处处有通道？市场准入和卫生技术评估的最新发展概览（第15部分）
Sreeram V Ramagopalan,Annie Jullien Pannelay
Sreeram V Ramagopalan
In this update we examine the inaugural report of the Health Economics Methods Advisory group on defining appropriate benefits for economic evaluation and the responses it has generated. We also review recent research on the timeliness of c...
Healthcare resource utilization and costs in patients with multiple myeloma administered ciltacabtagene autoleucel in outpatient versus inpatient settings after one to three prior lines of therapy [0.03%]
接受cilta-cel治疗的多发性骨髓瘤患者在门诊和住院环境下的医疗资源利用和成本：一线至三线治疗后的一项回顾性研究
Murali Janakiram,Sabyasachi Ghosh,Victoria Alegria et al.
Murali Janakiram et al.
Background: Ciltacabtagene autoleucel (cilta-cel) was approved for patients with relapsed or refractory multiple myeloma who received 1-3 prior lines of therapy in April 2024. Although traditionally administered inpatient (IP), there is an ...
Observational Study
Journal of comparative effectiveness research. 2026 Jul;15(7):e260052. DOI:10.57264/cer-2026-0052 2026
Considerations for assessing the feasibility of network meta-analysis of seasonal vaccines [0.03%]
开展季节性疫苗网络 meta 分析可行性评价的考虑因素
Allie Cichewicz,Marissa Betts,Narcisa Mesaros et al.
Allie Cichewicz et al.
Aim: Network meta-analyses (NMAs) of seasonal vaccines face distinct challenges that can compromise the validity and relevance of findings. While established frameworks offer guidance for evaluating the feasibility of NMAs, they do not addr...
Covariate selection and adjustment for efficacy and safety endpoints in indirect comparative effectiveness analyses of CAR-T-cell therapies for large B-cell lymphoma: a systematic review [0.03%]
CAR-T细胞疗法治疗大B细胞淋巴瘤的间接疗效和安全性分析中的协变量选择与调整：系统评价
Marie A-C Neumann,Jonas Jost,Sybille Riou et al.
Marie A-C Neumann et al.
Aim: Several CAR-T cell therapies have received regulatory approval from both the US FDA and the EMA for the treatment of large B-cell lymphoma. However, direct comparative trials between CAR-T cell therapies are lacking, mainly due to diff...
Acthar Gel treatment in patients with rheumatoid arthritis, systemic lupus erythematosus, or dermatomyositis/polymyositis: analysis of physician-reported charts [0.03%]
艾 ча ω 胶治疗类风湿性关节炎、系统性红斑狼疮或多发性肌炎/皮肌炎患者的疗效分析：基于医师报告的病历资料
Kyle Hayes,Amit Patel,Priyanka P Shanbhag et al.
Kyle Hayes et al.
Aim: To examine the characteristics, treatment patterns, and physicians' assessments of outcomes for patients with rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), or dermatomyositis/polymyositis (DM/PM) who received Acthar Ge...
Use of intracardiac echocardiography and three-dimensional mapping during catheter ablation for atrial fibrillation is associated with reduced complications: a retrospective analysis of United States Medicare Fee-For-Service Database [0.03%]
ICE和三维标测技术用于导管消融治疗房颤可减少并发症：美国Medicare数据库回顾性分析
Yiran Rong,Tom Wei,Kevin Corriveau et al.
Yiran Rong et al.
Aim: This retrospective cohort study assessed differences in procedure-related complications and death among old patients with atrial fibrillation (AF) undergoing catheter ablation (CA) procedure with versus without use of intracardiac echo...
Comparative efficacy and safety of olezarsen versus volanesorsen for familial chylomicronemia syndrome: a matching-adjusted indirect comparison [0.03%]
奥利扎尔森与沃拉内索尔恩治疗家族性高脂血症的疗效和安全性：一种匹配调整后的间接比较分析
Handrean Soran,Asia Sikora Kessler,Montserrat Vera-Llonch et al.
Handrean Soran et al.
Background: Familial chylomicronemia syndrome (FCS) is a rare genetic disorder characterized by severe hypertriglyceridemia causing recurrent acute pancreatitis (AP). Since FCS is a genetic deficiency in functional lipoprotein lipase, conve...