Methodological pitfalls in indirect treatment comparisons: insights from a recent systematic review and analysis for C3 glomerulopathy [0.03%]
间接治疗比较中的方法学陷阱：来自C3肾小球病的最新系统评价和分析的启示
Brian Hutton,James Fotheringham,Andrew Ervin et al.
Brian Hutton et al.
Aim: Indirect treatment comparisons (ITCs), as outlined in NICE and ISPOR guidance, require careful evaluation of cross-trial heterogeneity to ensure valid comparisons, particularly in rare diseases with limited evidence. C3 glomerulopathy ...
Treatment gaps in osteoporosis care following recurrent fractures: a nationwide cohort study [0.03%]
多次骨折后骨质疏松症治疗的缺口：一项全国性队列研究
Hyun Jin Han,Miryoung Kim,Eyoung Wang et al.
Hyun Jin Han et al.
Aim: This nationwide cohort study primarily aimed to descriptively characterize real-world treatment patterns, including treatment initiation, adherence, treatment duration and discontinuation of the first treatment drug, among patients who...
Systematic review and network meta-analysis of the efficacy, safety and tolerability of xanomeline plus trospium chloride compared with eight oral antipsychotics for the acute treatment of schizophrenia [0.03%]
系统综述与网络meta分析：评价扎莫利丁联合曲司氯铵与8种口服抗精神病药物急性治疗精神分裂症的疗效、安全性和耐受性比较
Conor Hickey,Matthew F Sidovar,Andrea Garcia et al.
Conor Hickey et al.
Aim: The recently approved first-in-class combination therapy xanomeline/trospium chloride (KarXT) demonstrated superiority over placebo in three randomized controlled trials (RCTs) of adults with schizophrenia. This analysis investigates i...
Effect of dose tapering policy on the prescription of advanced therapy for rheumatoid arthritis: a retrospective analysis of clinical and cost outcomes in Taiwan [0.03%]
剂量递减政策对台湾类风湿关节炎患者使用生物制剂的影响：临床及经济效益的回顾性分析
Ko-Jen Li,Chao-Hsiun Tang,Chia-Li Chang et al.
Ko-Jen Li et al.
Aim: To evaluate the impact of the Taiwan National Health Insurance program policy for advanced rheumatoid arthritis (aRA) therapies on treatment prescription patterns and costs in patients with rheumatoid arthritis (RA). Materials & method...
Mortality risk estimation for autistic older adults: comparing novel machine-learning derived weights versus standard weights for the Charlson Comorbidity Index [0.03%]
自闭症老年人死亡风险估计：新型机器学习派生权重与Charlson合并症指数标准权重的比较
Madison Blake,Melica Nikahd,J Madison Hyer et al.
Madison Blake et al.
Aim: We aimed to compare Quan and colleagues (2011) established weights for the Charlson Comorbidity Index (CCI) conditions to autism-specific weights for predicting mortality risk in autistic older adults. Materials & methods: We used inpa...
Validity of HINT-8 in evaluating health-related quality of life among cervical cancer patients [0.03%]
HINT-8在评估宫颈癌患者生活质量有效性的研究
Ah-Yeon Lee,Soo Hyeon Lee,Min-Ju Kim et al.
Ah-Yeon Lee et al.
Aim: Cervical cancer, caused primarily by human papillomavirus infection, affects patients' health-related quality of life (HRQoL). Despite research on quality of life in cancer patients, studies using the HINT-8 instrument, especially for ...
Transparency in positive airway pressure therapy trials: an evaluation of reporting quality [0.03%]
有关气道正压治疗试验透明性的报道：对报道质量的评估
Petra Stazić Kunčić,Diana Gujinović,Renata Pecotić et al.
Petra Stazić Kunčić et al.
Aim: Accurate and detailed reporting of nonpharmacological interventions such as positive airway pressure (PAP) therapy is essential for reproducibility, yet previous research shows frequent reporting deficiencies. Due to the complexity of ...
Understanding the economic and healthcare burden of metabolic dysfunction-associated steatohepatitis: a real-world claims data analysis from Germany [0.03%]
理解与代谢紊乱相关脂肪肝炎的经济和医疗负担：来自德国的真实世界理赔数据分析
Frank Tacke,Yestle Kim,Jennifer S Haas et al.
Frank Tacke et al.
Aim: Metabolic dysfunction-associated steatohepatitis (MASH) is a progressive form of metabolic dysfunction-associated steatotic liver disease, linked to hepatic and extra-hepatic complications and substantial healthcare costs. Despite its ...
Clinical effectiveness of a digitally delivered balance program for older adults: a nonrandomized controlled trial [0.03%]
老年人数字化平衡训练程序临床效果的非随机对照试验
Folasade Phillips,Sandhya Yadav,Cynthia Castro Sweet et al.
Folasade Phillips et al.
Aim: To evaluate the clinical effectiveness of a digitally delivered balance program relative to an attention-control comparison group in older adults at risk for falls. Materials & methods: This nonrandomized controlled trial recruited adu...
Real-world comparative effectiveness of analogue and human insulin on glycemic control in children and adolescents with Type 1 diabetes in Lebanon using continuous glucose monitoring data [0.03%]
使用连续葡萄糖监测数据评估黎巴嫩1型糖尿病儿童和青少年中人胰岛素与类似物疗效：真实世界研究
Sahar Masri,Manuel Albela,Iza Ciglenecki et al.
Sahar Masri et al.
Aim: In high income settings, insulin analogues were associated with improved glycemic control among adults with diabetes, mainly measured through HbA1c and hypoglycemic episodes. In low- and middle-income countries, especially those affect...