Feasibility, safety, and compliance in a randomized controlled trial of physical therapy for Parkinson's disease [0.03%]
帕金森病物理治疗随机对照试验的有效性、安全性和依从性研究
Jennifer L McGinley,Clarissa Martin,Frances E Huxham et al.
Jennifer L McGinley et al.
Both efficacy and clinical feasibility deserve consideration in translation of research outcomes. This study evaluated the feasibility of rehabilitation programs within the context of a large randomized controlled trial of physical therapy....
Improved Dynamic Postural Task Performance without Improvements in Postural Responses: The Blessing and the Curse of Dopamine Replacement [0.03%]
改善姿势任务的表现而没有提高姿势反应：多巴胺替代治疗的利与弊
K B Foreman,C Wisted,O Addison et al.
K B Foreman et al.
Introduction. Dopamine-replacement medications may improve mobility while not improving responses to postural challenges and could therefore increase fall risk. The purpose of this study was to measure reactive postural responses and gait-r...
Kristine K Hanna,Alice Cronin-Golomb
Kristine K Hanna
In Parkinson's disease (PD), both the patient and the health care provider look for ways to preserve the patient's quality of life. Many studies focus on the impact of depression and motor disability on poor life quality but neglect to exam...
Lack of Short-Term Effectiveness of Rotating Treadmill Training on Turning in People with Mild-to-Moderate Parkinson's Disease and Healthy Older Adults: A Randomized, Controlled Study [0.03%]
短期来看旋转跑步机训练对轻中度帕金森病患者和健康老年人转身动作无改善：一项随机对照研究
Marie E McNeely,Gammon M Earhart
Marie E McNeely
Since turning is often impaired in Parkinson's disease (PD) and may lead to falls, it is important to develop targeted treatment strategies for turning. We determined the effects of rotating treadmill training on turning in individuals with...
Adenosine A(2A) Receptor Antagonists Do Not Disrupt Rodent Prepulse Inhibition: An Improved Side Effect Profile in the Treatment of Parkinson's Disease [0.03%]
腺苷A2A受体拮抗剂不影响啮齿动物的prepulse抑制：帕金森病治疗中的副作用改善特征
Carina J Bleickardt,Abigail L Lashomb,Carrie E Merkel et al.
Carina J Bleickardt et al.
Parkinson's disease (PD) is characterized by loss of dopaminergic neurons in the substantia nigra. Current treatments for PD focus on dopaminergic therapies, including L-dopa and dopamine receptor agonists. However, these treatments induce ...
Upper Extremity Motor Learning among Individuals with Parkinson's Disease: A Meta-Analysis Evaluating Movement Time in Simple Tasks [0.03%]
帕金森病患者的上肢运动学习：一项关于简单任务中运动时间的元分析评价
K Felix,K Gain,E Paiva et al.
K Felix et al.
Motor learning has been found to occur in the rehabilitation of individuals with Parkinson's disease (PD). Through repetitive structured practice of motor tasks, individuals show improved performance, confirming that motor learning has prob...
Raúl de la Fuente-Fernández
Raúl de la Fuente-Fernández
Cognitive impairment and behavioural disorders are often encountered in subjects with Parkinson's disease (PD). A simple PD-related frontostriatal cognitive dysfunction (PDFCD) staging is proposed. Executive dysfunction and mental fatigue (...
Accuracy of fall prediction in Parkinson disease: six-month and 12-month prospective analyses [0.03%]
预测帕金森病患者跌倒的准确性：6个月和12个月前瞻性分析
Ryan P Duncan,Abigail L Leddy,James T Cavanaugh et al.
Ryan P Duncan et al.
Introduction. We analyzed the ability of four balance assessments to predict falls in people with Parkinson Disease (PD) prospectively over six and 12 months. Materials and Methods. The BESTest, Mini-BESTest, Functional Gait Assessment (FGA...
Progressive resistance exercise and Parkinson's disease: a review of potential mechanisms [0.03%]
有关进行性阻力锻炼与帕金森病的潜在作用机制综述
Fabian J David,Miriam R Rafferty,Julie A Robichaud et al.
Fabian J David et al.
This paper reviews the therapeutically beneficial effects of progressive resistance exercise (PRE) on Parkinson's disease (PD). First, this paper discusses the rationale for PRE in PD. Within the first section, the review discusses the cent...
Medication responsiveness of motor symptoms in a population-based study of Parkinson disease [0.03%]
基于人群的帕金森病患者中运动症状对药物的反应性研究
Yvette M Bordelon,Ron D Hays,Stefanie D Vassar et al.
Yvette M Bordelon et al.
We assessed degree of Parkinson disease motor symptom improvement with medication among subjects enrolled in an ongoing, population-based study in Central California. The motor section of the unified Parkinson disease rating scale (UPDRS) w...