The effects of instructions on dual-task walking and cognitive task performance in people with Parkinson's disease [0.03%]
指令对帕金森病患者双任务行走和认知任务表现的影响
Valerie E Kelly,Alexis J Eusterbrock,Anne Shumway-Cook
Valerie E Kelly
Gait impairments are prevalent among people with Parkinson's disease (PD). Instructions to focus on walking can improve walking in PD, but the use of such a cognitive strategy may be limited under dual-task walking conditions, when walking ...
Todd J Swick
Todd J Swick
Parkinson's disease (PD) has traditionally been characterized by its cardinal motor symptoms of bradykinesia, rigidity, resting tremor, and postural instability. However, PD is increasingly being recognized as a multidimensional disease ass...
Bright light therapy in Parkinson's disease: an overview of the background and evidence [0.03%]
帕金森病的光照治疗：背景与证据概览
Sonja Rutten,Chris Vriend,Odile A van den Heuvel et al.
Sonja Rutten et al.
Sleep disorders are common in Parkinson's disease (PD) and seem to be strongly associated with depression. It has been suggested that sleep disorders as well as depression are caused by a disturbed circadian rhythm. Indeed, PD patients are ...
Periodontal health and caries prevalence evaluation in patients affected by Parkinson's disease [0.03%]
帕金森病患者的牙周健康和龋齿患病率评估
Marco Cicciù,Giacomo Risitano,Giuseppe Lo Giudice et al.
Marco Cicciù et al.
Parkinson's disease (PD) is a progressive neurodegenerative disorder related to the loss or absence of dopaminergic neurons in the brain. These deficits result in slowness of movement, tremor, rigidity, and dysfunction of behaviour. These s...
Factors influencing quality of life in caregivers of people with Parkinson's disease and implications for clinical guidelines [0.03%]
帕金森病照料者生活质量的影响因素及对临床指南的启示
D Morley,S Dummett,M Peters et al.
D Morley et al.
The quality of life (QoL) of informal caregivers can be adversely affected by a number of factors. This issue, however, has not been well explored for carers of people with Parkinson's (PwP), with research largely restricted to the assessme...
Anna Rosa Carta,Andrea Giuffrida,Gilberto Fisone
Anna Rosa Carta
A Link between Autophagy and the Pathophysiology of LRRK2 in Parkinson's Disease [0.03%]
连接自噬与帕金森病中LRRK2的病理生理学之间的联系
Patricia Gómez-Suaga,Elena Fdez,Marian Blanca Ramírez et al.
Patricia Gómez-Suaga et al.
Parkinson's disease is a debilitating neurodegenerative disorder, and its molecular etiopathogenesis remains poorly understood. The discovery of monogenic forms has significantly advanced our understanding of the molecular mechanisms underl...
Effect of deep brain stimulation on speech performance in Parkinson's disease [0.03%]
大脑深部刺激对帕金森病患者言语功能的影响研究进展
Sabine Skodda
Sabine Skodda
Deep brain stimulation (DBS) has been reported to be successful in relieving the core motor symptoms of Parkinson's disease (PD) and motor fluctuations in the more advanced stages of the disease. However, data on the effects of DBS on speec...
Should One Measure Balance or Gait to Best Predict Falls among People with Parkinson Disease? [0.03%]
应测量平衡功能还是步态以预测帕金森病患者的跌倒风险？
Ryan P Duncan,Gammon M Earhart
Ryan P Duncan
Introduction. We aimed to determine whether gait velocity is as useful as a balance test, a self-report measure of freezing of gait (FOG), and/or a measure of motor symptom severity for predicting falls among people with Parkinson Disease (...
John W Wright,Joseph W Harding
John W Wright
Parkinson's disease (PD) has become a major health problem affecting 1.5% of the world's population over 65 years of age. As life expectancy has increased so has the occurrence of PD. The primary direct consequence of this disease is the lo...