Parkinson's disease and mesenchymal stem cells: potential for cell-based therapy [0.03%]
间充质干细胞与帕金森病细胞治疗的潜能研究进展
Masaaki Kitada,Mari Dezawa
Masaaki Kitada
Cell transplantation is a strategy with great potential for the treatment of Parkinson's disease, and many types of stem cells, including neural stem cells and embryonic stem cells, are considered candidates for transplantation therapy. Mes...
Postmortem Interval Influences α-Synuclein Expression in Parkinson Disease Brain [0.03%]
死后间隔时间对帕金森病脑内α-突触核蛋白表达的影响
Alexandra Dumitriu,Carlee Moser,Tiffany C Hadzi et al.
Alexandra Dumitriu et al.
Duplications and triplications of the α-synuclein (SNCA) gene increase risk for PD, suggesting increased expression levels of the gene to be associated with increased PD risk. However, past SNCA expression studies in brain tissue report in...
Web-based assessment of visual and visuospatial symptoms in Parkinson's disease [0.03%]
基于网络的帕金森病视觉和空间症状评估
Melissa M Amick,Ivy N Miller,Sandy Neargarder et al.
Melissa M Amick et al.
Visual and visuospatial dysfunction is prevalent in Parkinson's disease (PD). To promote assessment of these often overlooked symptoms, we adapted the PD Vision Questionnaire for Internet administration. The questionnaire evaluates visual a...
LSVT LOUD and LSVT BIG: Behavioral Treatment Programs for Speech and Body Movement in Parkinson Disease [0.03%]
用于帕金森病的言语和身体运动的行为治疗方法 LSVT LOUD 和 LSVT BIG
Cynthia Fox,Georg Ebersbach,Lorraine Ramig et al.
Cynthia Fox et al.
Recent advances in neuroscience have suggested that exercise-based behavioral treatments may improve function and possibly slow progression of motor symptoms in individuals with Parkinson disease (PD). The LSVT (Lee Silverman Voice Treatmen...
Altered Dynamic Postural Control during Step Turning in Persons with Early-Stage Parkinson's Disease [0.03%]
帕金森病早期患者的动态姿势控制变化步态期转身分析
Jooeun Song,Susan Sigward,Beth Fisher et al.
Jooeun Song et al.
Persons with early-stage Parkinson's disease (EPD) do not typically experience marked functional deficits but may have difficulty with turning tasks. Studies evaluating turning have focused on individuals in advanced stages of the disease. ...
Improving community healthcare for patients with Parkinson's disease: the dutch model [0.03%]
改善帕金森病患者的社区医疗保健：荷兰模式
S H J Keus,L B Oude Nijhuis,M J Nijkrake et al.
S H J Keus et al.
Because of the complex nature of Parkinson's disease, a wide variety of health professionals are involved in care. Stepwise, we have addressed the challenges in the provision of multidisciplinary care for this patient group. As a starting p...
Dyskinesias and treatment with pramipexole in patients with Parkinson's disease [0.03%]
普拉克索治疗帕金森病患者的运动障碍症状疗效观察
John C P Piedad,Andrea E Cavanna
John C P Piedad
Dopamine agonists such as pramipexole (PPX) have first been proposed as adjunctive treatment to levodopa (L-DOPA) for patients with Parkinson's disease (PD) and then as a monotherapy alternative to alleviate dyskinesia. Treatment with PPX h...
Are verbal fluency and nonliteral language comprehension deficits related to depressive symptoms in Parkinson's disease? [0.03%]
帕金森病的抑郁症状与语言流畅度和非字面意思理解缺陷有关吗？
Christina Tremblay,Oury Monchi,Carol Hudon et al.
Christina Tremblay et al.
Depression in Parkinson's disease (PD) is frequently associated with executive deficits, which can influence nonliteral comprehension and lexical access. This study explores whether depressive symptoms in PD modulate verbal fluency and nonl...
Posture and locomotion coupling: a target for rehabilitation interventions in persons with Parkinson's disease [0.03%]
姿势和步态耦合：帕金森病患者的康复目标
Marie-Laure Mille,Robert A Creath,Michelle G Prettyman et al.
Marie-Laure Mille et al.
Disorders of posture, balance, and gait are debilitating motor manifestations of advancing Parkinson's disease requiring rehabilitation intervention. These problems often reflect difficulties with coupling or sequencing posture and locomoti...
Risk of falls in Parkinson's disease: a cross-sectional study of 160 patients [0.03%]
帕金森病患者跌倒的危险因素：160例患者的横断面研究
Ana Contreras,Francisco Grandas
Ana Contreras
Falls are a major source of disability in Parkinson's disease. Risk factors for falling in Parkinson's disease remain unclear. To determine the relevant risk factors for falling in Parkinson's disease, we screened 160 consecutive patients w...