A preliminary report on disordered speech with deep brain stimulation in individuals with Parkinson's disease [0.03%]
帕金森病患者深部脑刺激引起失序语言的初步报告
Christopher Dromey,Suzy Bjarnason
Christopher Dromey
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) has proven effective in treating the major motor symptoms of advanced Parkinson's disease (PD). The aim of this study was to learn which laryngeal and articulatory acoustic featu...
Deep brain stimulation of caudal zona incerta and subthalamic nucleus in patients with Parkinson's disease: effects on voice intensity [0.03%]
脑深部电刺激尾状区纹状体联合苍白球外侧核和内侧丘脑核治疗帕金森病患者：对声音强度的影响
Sofie Lundgren,Thomas Saeys,Fredrik Karlsson et al.
Sofie Lundgren et al.
Deep brain stimulation of the subthalamic nucleus (STN-DBS) in patients with Parkinson's disease (PD) affects speech inconsistently. Recently, stimulation of the caudal zona incerta (cZi-DBS) has shown superior motor outcomes for PD patient...
Gait difficulty, postural instability, and muscle weakness are associated with fear of falling in people with Parkinson's disease [0.03%]
帕金森病患者的步态障碍、姿势不稳和肌肉无力与跌倒恐惧有关
Margaret K Y Mak,Marco Y C Pang,Vincent Mok
Margaret K Y Mak
The present study aimed to examine the contribution of gait impairment, postural stability and muscle weakness to the level of fear of falling in people with Parkinson's disease (PD). Fifty-seven community-dwelling individuals with PD compl...
Imbalanced Dopaminergic Transmission Mediated by Serotonergic Neurons in L-DOPA-Induced Dyskinesia [0.03%]
多巴胺递质不平衡通过五羟色胺神经元在左旋多巴诱发的异动症中的介导作用
Sylvia Navailles,Philippe De Deurwaerdère
Sylvia Navailles
L-DOPA-induced dyskinesias (LIDs) are one of the main motor side effects of L-DOPA therapy in Parkinson's disease. The review will consider the biochemical evidence indicating that the serotonergic neurons are involved in the dopaminergic e...
Deep brain stimulation of caudal zona incerta and subthalamic nucleus in patients with Parkinson's disease: effects on diadochokinetic rate [0.03%]
丘脑底核和腹中束区深部电刺激对帕金森病患者叠加运动速率的影响
Fredrik Karlsson,Elin Unger,Sofia Wahlgren et al.
Fredrik Karlsson et al.
The hypokinetic dysarthria observed in Parkinson's disease (PD) affects the range, speed, and accuracy of articulatory gestures in patients, reducing the perceived quality of speech acoustic output in continuous speech. Deep brain stimulati...
Lingual kinematics in dysarthric and nondysarthric speakers with Parkinson's disease [0.03%]
帕金森病构音障碍和非构音障碍患者的言语运动特性研究
Min Ney Wong,Bruce E Murdoch,Brooke-Mai Whelan
Min Ney Wong
Articulatory dysfunction is recognised as a major contributor to the speech disturbances seen in Parkinson's disease (PD). The present study aimed to compare lingual kinematics during consonant production within a sentence in eight dysarthr...
Karen Chenausky,Joel Macauslan,Richard Goldhor
Karen Chenausky
According to the U.S. National Institutes of Health, approximately 500,000 Americans have Parkinson's disease (PD), with roughly another 50,000 receiving new diagnoses each year. 70%-90% of these people also have the hypokinetic dysarthria ...
A perfusion MRI study of emotional valence and arousal in Parkinson's disease [0.03%]
帕金森病的情绪价值和唤醒的灌注磁共振成像研究
Sunsern Limsoontarakul,Meghan C Campbell,Kevin J Black
Sunsern Limsoontarakul
Background. Brain regions subserving emotion have mostly been studied using functional magnetic resonance imaging (fMRI) during emotion provocation procedures in healthy participants. Objective. To identify neuroanatomical regions associate...
Assessment of prosodic communicative efficiency in Parkinson's disease as judged by professional listeners [0.03%]
帕金森病韵律交际效率的专业听者评价
Heidi Martens,Gwen Van Nuffelen,Patrick Cras et al.
Heidi Martens et al.
This study examines the impact of Parkinson's disease (PD) on communicative efficiency conveyed through prosody. A new assessment method for evaluating productive prosodic skills in Dutch speaking dysarthric patients was devised and tested ...
Lorinda C Kwan,Tara L Whitehill
Lorinda C Kwan
A few clinical reports and empirical studies have suggested a possible deficit in the perception of speech in individuals with Parkinson's disease. In this paper, these studies are reviewed in an attempt to support clinical anecdotal observ...