Conventional Risk Factors, Telomere Length, and Ischemic Heart disease: Insights into the Mediation Analysis [0.03%]
传统危险因素、端粒长度和缺血性心脏病：中介分析的新见解
Shobhit Piplani,Madhav Prabhu,Nadezdha Niyarah Alemao et al.
Shobhit Piplani et al.
Telomere length is regarded as a potential biomarker of biological ageing and is associated with various age-related diseases, such as ischemic heart disease (IHD), myocardial infarction, peripheral vascular disease, and cancer. As there is...
Analysis of Xq27.3 Fragility Using the Micronucleus-Fluorescence In situ Hybridization Assay [0.03%]
采用微核-荧光原位杂交技术分析Xq27.3脆性部位
Leyla Özer,Hatice Ilgın Ruhi,Işık Bökesoy
Leyla Özer
Chromosome fragile sites tend to form gap or break in chromosomes when the cells are exposed to replication stress. Folic acid deprivation in the culture medium induces folate-sensitive rare fragile sites, such as FRAXA which is responsible...
Radiation-induced Chromosome Instability: The Role of Dose and Dose Rate [0.03%]
辐射诱导的染色体不稳定性：剂量和剂量率的作用
Eman Mohammed Elbakrawy,Mark A Hill,Munira A Kadhim
Eman Mohammed Elbakrawy
Nontargeted effects include radiation-induced genomic instability (RIGI) which is observed in the progeny of cells exposed to ionizing radiation and can be manifested in different ways, including chromosomal instability and micronucleus (MN...
Development of Dose-Response Calibration Curve for Dicentric Chromosome Induced by X-Rays [0.03%]
X射线诱导dicentric染色体剂量效应校准曲线的建立研究
Yanti Lusiyanti,Mukh Syaifudin,Tuti Budiantari et al.
Yanti Lusiyanti et al.
Chromosome aberration is a biomarker that has been used as a standard tool in biological dosimetry (biodosimetry) of individuals after exposure to ionizing radiation. It is based mainly on the induction of dicentric chromosomes - one of the...
Development of Dose-Response Calibration Curve for Dicentric Chromosome Induced by X-Rays [0.03%]
X射线诱发二цentric染色体剂量效应校准曲线的建立研究
Yanti Lusiyanti,Mukh Syaifudin,Tuti Budiantari et al.
Yanti Lusiyanti et al.
Chromosome aberration is a biomarker that has been used as a standard tool in biological dosimetry (biodosimetry) of individuals after exposure to ionizing radiation. It is based mainly on the induction of dicentric chromosomes - one of the...
A Child with Partial Trisomy 4 (q26 - qterminal) Resulting from Paternally Inherited Translocation (4:18) Associated with Multiple Congenital Anomalies and Death [0.03%]
一个因父亲遗传的易位（4：18）而导致4号染色体部分三体现（qter-q26），并伴有多种先天畸形和死亡的患儿报告
Abhik Chakraborty,Santosh Kumar Panda,Nirmal Kumar Mohakud et al.
Abhik Chakraborty et al.
Parental balanced reciprocal translocations can result in partial aneuploidy in the offspring due to unbalanced meiotic segregation during gametogenesis. Herein, we report the phenotypic and cytogenetic characterization in a 9-day-old male ...
Case Reports
Genome integrity. 2019 May 24:10:1. DOI:10.4103/genint.genint_4_18 2019
Micronucleus Assay-based Evaluation of Radiosensitivity of Lymphocytes among Inhabitants Living in High Background Radiation Area of Mamuju, West Sulawesi, Indonesia [0.03%]
印度尼西亚西苏拉威斯马穆朱高本底辐射区居民淋巴细胞放射敏感性的微核试验评估
Mukh Syaifudin,Vira Putri Defiyandra,Siti Nurhayati et al.
Mukh Syaifudin et al.
Naturally occurring radiation can be found all around us and account for most of the radiation received by human beings each year. Indonesia has a region with high-dose natural radiation located in the suburb of West Sulawesi province with ...
The Frequency of Lymphocytes Containing Dumbbell-Shaped Nuclei Depends on Ionizing Radiation Dose and Correlates with Appearance of Chromosomal Aberrations [0.03%]
染色体异常出现的哑铃形淋巴细胞频率依赖于电离辐射剂量且与染色体异常相关性较大
Viacheslav Yu Kravtsov,Alexandra A Livanova,Oleg V Belyakov et al.
Viacheslav Yu Kravtsov et al.
Nuclear anomalies of different types appear in cells in response to the action of ionizing radiation after the passage of the first mitotic division. In this article, we present the results of the study of the frequency of occurrence of thr...
The Application of Imaging Flow Cytometry to High-Throughput Biodosimetry [0.03%]
高通量生物剂量学中影像式流动细胞术的应用研究进展
Ruth C Wilkins,Matthew A Rodrigues,Lindsay A Beaton-Green
Ruth C Wilkins
Biodosimetry methods, including the dicentric chromosome assay, the cytokinesis-block micronucleus assay and the γH2AX marker of DNA damage are used to determine the dose of ionizing radiation. These techniques are particularly useful when...
Dimphy Zeegers,Shriram Venkatesan,Shu Wen Koh et al.
Dimphy Zeegers et al.
Humans are exposed to ionizing radiation not only through background radiation but also through the ubiquitous presence of devices and sources that generate radiation. With the expanded use of radiation in day-to-day life, the chances of ac...