Establishment of a Radiation Dose-Response Calibration Curve Using a Rapid Cytokinesis-block Micronucleus Assay for Dose Assessment of Medical Radiation Equipment [0.03%]
利用快速有丝分裂阻滞 micronucleus 试验建立辐射剂量效应校准曲线进行医疗照射设备的剂量评估研究
Ji Young Kim,Seong-Jun Cho,Hoon Choi et al.
Ji Young Kim et al.
Dicentric chromosome analysis (DCA) has limitations in its use for the evaluation of the radiation dose upon the development of medical radiation equipment due to its time/labour-consuming procedure and the requirement of highly trained exp...
Transforming Healthcare: Artificial Intelligence (AI) Applications in Medical Imaging and Drug Response Prediction [0.03%]
医疗保健转型：医学影像和药物反应预测中的人工智能应用
Karthik Prathaban,M Prakash Hande
Karthik Prathaban
Artificial intelligence (AI) offers a broad range of enhancements in medicine. Machine learning and deep learning techniques have shown significant potential in improving diagnosis and treatment outcomes, from assisting clinicians in diagno...
Androgen Receptor Influenced Recurrence Score Correlation in Hormone Positive and HER2 Negative Breast Cancer Indian Patients: A Comparative Approach [0.03%]
雄激素受体影响激素阳性HER2阴性乳腺癌印度患者的复发评分：一种比较方法
Amit Roy Chowdhury,Somya Saswati Swain,Sandip Kumar Mohanty et al.
Amit Roy Chowdhury et al.
Breast cancer (BC) recurrence is a major concern for both patients and healthcare providers. Accurately predicting the risk of BC recurrence can help guide treatment decisions and improve patient outcomes for a disease-free survival. There ...
Role of Mitogen-Activated Protein (MAP) Kinase Pathways in Metabolic Diseases [0.03%]
MAP激酶途径在代谢性疾病中的作用
Gavin Yong Quan Ng,Zachary Wai-Loon Loh,David Y Fann et al.
Gavin Yong Quan Ng et al.
Physiological processes that govern the normal functioning of mammalian cells are regulated by a myriad of signalling pathways. Mammalian mitogen-activated protein (MAP) kinases constitute one of the major signalling arms and have been broa...
Telomerase Inhibition by MST-312 Sensitizes Breast Cancer Cells to the Anti-cancer Properties of Plumbagin [0.03%]
MST-312通过抑制端粒酶增强 plumbagin的抗肿瘤作用以杀死乳腺癌细胞
Safoura Sameni,Ramya Viswanathan,Gavin Yong-Quan Ng et al.
Safoura Sameni et al.
Breast cancer is the most common cause of malignancy and the second most common cause of death due to cancer in women. This heterogeneous disease is currently broadly classified as estrogen receptor (ER), progesterone receptor (PR) positive...
Therapeutic Fractional Doses of Ionizing Radiation Promote Epithelial-Mesenchymal Transition, Enhanced Invasiveness, and Altered Glycosylation in MCF-7 Breast Cancer Cells [0.03%]
分次电离辐射的治疗剂量可促进MCF-7乳腺癌细胞上皮间质转化、侵袭力增强及糖基化改变
Raheem Al-Abedi,Seda Tuncay Cagatay,Ammar Mayah et al.
Raheem Al-Abedi et al.
The clinical outcome of radiation therapy is restricted due to the acquired radio-resistance of a subpopulation of tumour cells that may cause tumour relapse and distant metastasis. While the effects of ionizing radiation (IR) such as DNA d...
The Detection of DNA Damage Response in MCF7 and MDA-MB-231 Breast Cancer Cell Lines after X-ray Exposure [0.03%]
X射线照射后在MCF7和MDA-MB-231乳腺癌细胞系中检测DNA损伤反应
Alkhansa Mahmoud,Arianna Casciati,Zuki Abu Bakar et al.
Alkhansa Mahmoud et al.
Radiotherapy is one of the main options to cure and control breast cancer. The aim of this study was to investigate the sensitivity of two human breast cancer cell lines, MCF7 and MDA-MD-231, to radiation exposure at timepoints 4 h and 24 h...
Oxidative Damage Induced Telomere Mediated Genomic Instability in Cells from Ataxia Telangiectasia Patients [0.03%]
氧化损伤诱导的阿佩尔-泰勒氏症患者的细胞端粒介导的基因组不稳定性研究
Prarthana Srikanth,Amit Roy Chowdhury,Grace Kah Mun Low et al.
Prarthana Srikanth et al.
Our cellular genome is susceptible to cytotoxic lesions which include single strand breaks and double strand breaks among other lesions. Ataxia telangiectasia mutated (ATM) protein was one of the first DNA damage sensor proteins to be disco...
Detection of Radiation-Induced DNA Damage in Breast Cancer Patients by Using Gamma H2AX Biomarker: A Possible Correlation with Their Body Mass Index [0.03%]
伽玛H2AX生物标志物检测乳腺癌患者的放射诱导DNA损伤：与体质指数的相关性研究
Alkhansa S Mahmoud,Ammar M E Hassan,Amna A Ali et al.
Alkhansa S Mahmoud et al.
Radiotherapy is one of the most important options for treating breast cancer in humans. The development of biomarkers to monitor radiosensitivity is scarce. The aim of this study is to investigate the γH2AX levels in the human blood sample...
Association of Telomere Length and Serum Vitamin D Levels with Type 2 Diabetes Mellitus and its Related Complications: A Possible Future Perspective [0.03%]
端粒长度和血清维生素D水平与2型糖尿病及其相关并发症的关系：未来可能的研究视角
C Akash,Madhav Prabhu,Arif Maldar et al.
C Akash et al.
Evidence show that shortened telomere length (TL) and low Vitamin D levels can increase the risk of type 2 diabetes mellitus (T2DM) and its associated complications. T2DM has been considered as an age-related disease, it may be associated w...