Feifei Ni,Yangyang Chen,Ze Wang et al.
Feifei Ni et al.
Graphene and its derivatives are widely used in tissue-engineering scaffolds, especially in the form of hydrogels. This is due to their biocompatibility, electrical conductivity, high surface area, and physicochemical versatility. They are ...
Scaffold-mediated liver regeneration: A comprehensive exploration of current advances [0.03%]
肝脏再生的支架研究:目前的研究进展及未来方向
Supriya Bhatt S,Jayanthi Krishna Kumar,Shurthi Laya et al.
Supriya Bhatt S et al.
The liver coordinates over 500 biochemical processes crucial for maintaining homeostasis, detoxification, and metabolism. Its specialized cells, arranged in hexagonal lobules, enable it to function as a highly efficient metabolic engine. Ho...
Discovery of bioactive peptides as therapeutic agents for skin wound repair [0.03%]
皮肤伤口修复治疗剂生物活性肽的发现
Nur Izzah Md Fadilah,Nurul Aqilah Shahabudin,Raniya Adiba Mohd Razif et al.
Nur Izzah Md Fadilah et al.
Short sequences of amino acids called peptides have a wide range of biological functions and the potential to treat a number of diseases. Bioactive peptides can be derived from different sources, including marine organisms, and synthetic de...
Engineered pre-dentin with well-aligned hierarchical mineralized collagen fibril bundles promote bio-root regeneration [0.03%]
具有高度排列的类骨矿化胶原纤维束的工程前期牙本质促进生物根再生
Lei Hu,Dongmei Cheng,Xin Yuan et al.
Lei Hu et al.
Stem cell-mediated bio-root regeneration is an alternative tooth replacement strategy; however, physiologically functional bio-root regeneration with distinctive dentin structure remains challenging. In this study, the distinct arrangements...
Exosomal non-coding RNAs: Emerging insights into therapeutic potential and mechanisms in bone healing [0.03%]
外泌体非编码RNA:骨愈合治疗潜力及机制新见解
Huixin Shi,Yang Yang,Hao Xing et al.
Huixin Shi et al.
Exosomes are nano-sized extracellular vesicles (EVs) released by diverse types of cells, which affect the functions of targeted cells by transporting bioactive substances. As the main component of exosomes, non-coding RNA (ncRNA) is demonst...
Photocuring 3D printing technology as an advanced tool for promoting angiogenesis in hypoxia-related diseases [0.03%]
光固化3D打印技术作为促进缺氧相关疾病血管生成的先进工具
Sang Yoon Lee,Huynh Dai Phuc,Soong Ho Um et al.
Sang Yoon Lee et al.
Three-dimensional (3D) bioprinting has emerged as a promising strategy for fabricating complex tissue analogs with intricate architectures, such as vascular networks. Achieving this necessitates bioink formulations that possess highly print...
Enhanced interaction between genome-edited mesenchymal stem cells and platelets improves wound healing in mice [0.03%]
基因编辑的间充质干细胞与血小板相互作用增强可改善小鼠伤口愈合
De-Yong Li,Yu-Meng Li,Dan-Yi Lv et al.
De-Yong Li et al.
Impaired wound healing poses a significant burden on the healthcare system and patients. Stem cell therapy has demonstrated promising potential in the treatment of wounds. However, its clinical application is hindered by the low efficiency ...
Vascularized characteristics and functional regeneration of three-dimensional cell reconstruction of oral mucosa equivalents based on vascular homeostasis phenotypic modification [0.03%]
基于血管稳态表型调控的口腔粘膜等效物三维细胞重建的血管化特征及功能再生
Lijuan Shi,Yiwen Xu,Jingying Li et al.
Lijuan Shi et al.
Our prior research has effectively developed tissue-engineered vascularized oral mucosa equivalents (VOME); however, challenges such as low repeatability and stability, as well as the inability to accurately replicate the complexity of real...
EVs from cells at the early stages of chondrogenesis delivered by injectable SIS dECM promote cartilage regeneration [0.03%]
早期软骨发生细胞来源的SIS dECM注射递送的外泌体促进软骨再生
Weilai Zhu,Jiaying Shi,Bowen Weng et al.
Weilai Zhu et al.
Articular cartilage defect therapy is still dissatisfactory in clinic. Direct cell implantation faces challenges, such as tumorigenicity, immunogenicity, and uncontrollability. Extracellular vesicles (EVs) based cell-free therapy becomes a ...
Dynamic three-dimensional coculture model: The future of tissue engineering applied to the peripheral nervous system [0.03%]
动态三维共培养模型:组织工程在周围神经系统应用的未来方向
William Choinière,Ève Petit,Vincent Monfette et al.
William Choinière et al.
Traumatic injuries to the peripheral nervous system (PNI) can lead to severe consequences such as paralysis. Unfortunately, current treatments rarely allow for satisfactory functional recovery. The high healthcare costs associated with PNS ...