Free energy simulations on a biomimetic glucose receptor: understanding the selectivity of GluHUT [0.03%]
类葡萄糖受体的自由能计算：GluHUT的选择性机制研究
Ryan Eades,Marko Hanzevacki,Adrian J Mulholland et al.
Ryan Eades et al.
The bicyclic glucose receptor GluHUT represents a significant advance in supramolecular chemistry, binding glucose in water with an association constant of approximately 18 000 M-1 and exhibiting exceptional selectivity. Elucidating the mol...
Tunable synaptic memory response using organic regioisomeric donor-acceptor-donor luminophore triads [0.03%]
基于有机区域异构体给体-受体-给体三联分子的可调式突触记忆响应
Mainak Bose,Manoj Kangsabanik,Dibyendu Dey et al.
Mainak Bose et al.
Modeling synaptic memory with small molecular compounds allows for replication of key features of biological learning and memory in a simplified, controllable, and tunable chemical system, where processes such as signal transmission, plasti...
Youhao Wei,Kengo Kasama,Antòn Igartua et al.
Youhao Wei et al.
Heteroaromatic scaffolds are central to modern medicinal chemistry. Methods that can reconfigure the core heterocycle of a molecule while preserving its substitution pattern would greatly streamline analogue synthesis and bioisosteric repla...
Enzymatically hydrolyzed oligosaccharide fingerprinting using nanopipettes at the single-molecule level [0.03%]
基于纳米移液管的单分子酶解寡糖指纹分析法
Qi-Yun Lu,Hui Ma,Shi-Guo Chen
Qi-Yun Lu
Enzymatic hydrolysis of oligosaccharides plays a pivotal role in important biological processes, but conventional analytical tools struggle to determine these functional components with single-monosaccharide resolution and ultrahigh sensiti...
Correction: Regioselective synthesis of aza-saccharins via anionic [1,4] Fries-type rearrangement of aryl sulfonimidoyl fluorides [0.03%]
关于芳基磺亚胺氟的阴离子[1,4] fries重排及aza-糖精的选择性合成的更正论文
Mario Leypold,Lorenzo Poli,Max Earl et al.
Mario Leypold et al.
[This corrects the article DOI: 10.1039/D6SC00432F.]. This journal is © The Royal Society of Chemistry.
Published Erratum
Chemical science. 2026 May 27. DOI:10.1039/d6sc90113a 2026
Boron buckminsterfullerene [0.03%]
硼富勒烯
Hyun Wook Choi,Yang-Yang Zhang,Deniz Kahraman et al.
Hyun Wook Choi et al.
Fullerenes, spherical molecules made entirely of carbon atoms, have played a foundational role in the birth of nanoscience. Despite extensive research, however, comparable structures composed of other elements have remained elusive, highlig...
Synthesis and machine learning techniques to enable data-driven investigation of supramolecular host-guest interactions [0.03%]
数据驱动超分子主客体相互作用研究的合成和机器学习方法学及相关应用基础研究
Alok Shaurya,Amir Hassan Bagherzadeh Mostaghimi,David R Turnbull et al.
Alok Shaurya et al.
The availability of large datasets such as the Protein DataBank and ChEMBL have allowed for rapid progress in developing machine learning tools for predicting the biological activity of organic small molecules. The binding between supramole...
Construction of axial chirality through addressing the meta constraint in the Catellani reaction [0.03%]
卡特拉尼反应中解除元定位规律以构建轴手性的研究
Jin Ge,Yaopeng Liu,Xi Wu et al.
Jin Ge et al.
Axially chiral biaryls represent an important class of atropisomers that are prevalent in organic ligands, bioactive molecules, and materials. Despite recent advances in the synthesis of atropisomers via the Catellani reaction, the construc...
Photochemical post-functionalization of polystyrene enables accelerated chemical recycling [0.03%]
光化学后官能化使聚苯乙烯加速化学回收成为可能
Stanley Lo,Angela Lin,Cher Tian Ser et al.
Stanley Lo et al.
Molecular post-modification design strategies that enable low-temperature pyrolysis of polystyrene (PS) remain an underexplored area. Conventional pyrolysis of PS demands heating above 400 °C, creating economic barriers to commercial-scale...
Nano-visualization of hydrogel dynamics via surface plasmon-enhanced aggregation-induced emission [0.03%]
基于表面等离子体增强聚集诱导发光的水凝胶动力学纳米可视化研究
Qing-Bo Liang,Zhao Li,Yu-Hua Weng et al.
Qing-Bo Liang et al.
Understanding conformational transitions in hydrogels is essential for deciphering their stimulus-responsive behavior, yet real-time, label-free monitoring at the nanoscale has remained a fundamental barrier. Here, we introduce surface plas...