Engineering strategies and translational progress in targeted nanoparticle drug delivery [0.03%]
靶向纳米颗粒药物递送的工程策略及转化进展
Nithya Ajay,Anu Shibi Anilkumar,Ramakrishnan Veerabathiran
Nithya Ajay
Introduction: Nanoparticle-based drug delivery has emerged as a transformative approach in modern therapeutics, offering improved targeting efficiency, enhanced pharmacokinetics, and reduced systemic toxicity compared to ...
PROTEX platforms as molecular navigators in oral squamous cell carcinoma [0.03%]
PROTEX平台作为口腔鳞状细胞癌的分子导航工具
Debnath Das,Sourabh Kumar,Nisha Bharti et al.
Debnath Das et al.
"Microneedles in breast cancer therapy: navigating treatment innovation amid biological and technological challenges" [0.03%]
乳腺癌治疗中的微针技术：在生物和科技挑战中探索治疗创新之路
Mokshitha Pachipala,J Joysa Ruby,Venkatesh Dinnekere Puttegowda
Mokshitha Pachipala
Breast cancer remains a leading cause of cancer-related morbidity and mortality worldwide, with conventional treatments frequently limited by systemic toxicity, multidrug resistance, and high recurrence rates, particularly in triple-negativ...
A narrative review on nanogel-based topical delivery of chemotherapeutic and phytoagents for non- melanoma skin cancer treatment [0.03%]
纳米凝胶基化学药物和植物药剂的局部递送治疗非黑色素瘤皮肤癌的文字叙述审查报告
Harshita Singh,Devika Unnithan,Nida Nehal et al.
Harshita Singh et al.
Introduction: Non-Melanoma Skin Cancer (NMSC) arises from oxidative stress induced by ultraviolet (UV) radiation, ongoing inflammation, and genetic mutations that promote cell growth. Mainstream treatment often faces chal...
Combination therapy strategies for diabetic foot ulcers: synthesizing antibiotics, growth factors, and nanocarriers in modern wound management [0.03%]
糖尿病足溃疡的联合治疗策略：抗生素、生长因子及纳米载体在现代创面管理中的应用展望
Priyanshu Pathak,Shatrudhan Prajapati,Shikha Yadav
Priyanshu Pathak
Diabetic foot ulcers (DFUs) are serious complications of diabetes, and consist of chronic wound healing, chronic biofilm infection, impaired angiogenesis, oxidized stress, and persistent inflammation. Standard treatments such as systemic an...
Integrative in vitro - in silico evaluation of β-carotene-loaded nanoliposomes for targeted therapy against prostate carcinoma (PC-3) cells [0.03%]
体外-体内的集成评价β-胡萝卜素载药纳米脂质体靶向治疗前列腺癌(PC-3)细胞的潜力
Mahmoud H Khedr,Ali G Asem,Ahmed A Elbadry et al.
Mahmoud H Khedr et al.
Aims: This study evaluated β-carotene-loaded lecithin nanoliposomes as a prostate cancer nanoplatform and assessed whether B-cell lymphoma 2 (Bcl-2) modulation could explain their activity. ...
Tumor spheroids: opportunities for in vitro validation of anticancer drugs in imaging and targeted drug delivery [0.03%]
肿瘤球体：体外验证抗癌药物的影像学和靶向给药机会
Amit Ranjan Maity,Thyageshwar Chandran,Surya K Ghosh
Amit Ranjan Maity
Naturally derived excipients in injectable nanomedicines: a systematic review of pharmacokinetic performance, regulatory readiness, and future quality by design perspectives [0.03%]
基于天然来源的注射用纳米药物辅料的药代动力学性能、监管和未来质量设计研究系统的回顾
Ghassan Sonji,Nada Sonji,Afaf El Katerji
Ghassan Sonji
Introduction: Naturally derived excipients such as lecithin, chitosan, and hyaluronic acid offer biocompatibility for injectable nanomedicines, although material variability may limit clinical translation. This systematic...
Flavonoid nanoformulations for cutaneous administration: overcoming delivery barriers for targeted therapeutics and bioavailability enhancement [0.03%]
用于皮肤给药的黄酮类纳米制剂：克服传递障碍，实现靶向治疗和生物利用度增强
Aya Said,Eman M El-Marakby,Mona M A Abdel-Mottaleb et al.
Aya Said et al.
Flavonoids represent one of the most pharmacologically diverse classes of natural polyphenols, demonstrating broad therapeutic potential in oncology, neurodegeneration, cardiovascular, and metabolic disorders. However, their clinical utilit...
Optimization of nanoemulsion formulations of Piper sarmentosum for topical application in skin cancer [0.03%]
猫薄荷素提取物纳米乳膏局部用药的优化配方及药效学研究
Bassam Mohamed Jawahar,Munira Shahbuddin,Raha Ahmad Raus et al.
Bassam Mohamed Jawahar et al.
Aims: Topical delivery for skin cancer treatment is a better alternative for a highly localized tumor and lower severity of adverse effects associated with oral or parental administration of chemotherapeutic drugs. Topica...