An integrated complete-genome sequencing and systems biology approach to predict antimicrobial resistance genes in the virulent bacterial strains of Moraxella catarrhalis [0.03%]
一种针对摩拉菌属细菌毒力菌株的预测抗菌药物耐药基因的整合全基因组测序和系统生物学方法
Sadia Afrin Bristy,Md Arju Hossain,Md Imran Hasan et al.
Sadia Afrin Bristy et al.
Moraxella catarrhalis is a symbiotic as well as mucosal infection-causing bacterium unique to humans. Currently, it is considered as one of the leading factors of acute middle ear infection in children. As M. catarrhalis is resistant to mul...
Effect of EGR1/LIPT1 regulatory axis on cuproptosis in chromophobe renal cell carcinoma [0.03%]
EGR1/LIPT1调节轴对嫌色肾细胞癌铜死亡的影响研究
Jingxian Luo,Mingqiang Su,Xianyong Li et al.
Jingxian Luo et al.
Renal cell carcinoma (RCC) is one of the most prevalent solid tumors, and chromophobe renal cell carcinoma (chRCC) is its third most common subtype. The cuproptosis has become a hot topic in the field of cancer treatment. This study aimed t...
Unraveling risk factors and transcriptomic signatures in liver cancer progression and mortality through machine learning and bioinformatics [0.03%]
通过机器学习和生物信息学解析肝癌进展和死亡的风险因素及转录组标志物
Tania Akter Asa,Md Ali Hossain,Md Shahjahan Ali et al.
Tania Akter Asa et al.
Liver cancer (LC) is the second leading cause of cancer-related deaths globally, yet the molecular mechanisms linking its progression with associated risk factors (RFs) remain poorly understood. To address this, we developed an integrative ...
Bioinformatics insights into plant genomic imprinting: approaches, challenges, and future perspectives [0.03%]
植物基因组印记的生物信息学见解：方法、挑战和未来展望
Xiaotong Jing,Xi Su,Quan Zou et al.
Xiaotong Jing et al.
Genomic imprinting is an epigenetic occurrence that results in the expression of alleles specific to the parent of origin, plays pivotal roles in plant development, stress adaptation, and agronomic trait regulation. While imprinting has bee...
Meiling Huang,Changjiao Yan,Rui Ling et al.
Meiling Huang et al.
Thyroid cancer is one of the most common endocrine diseases worldwide with phenotypic heterogeneity. Deubiquitinating enzymes (DUBs) participated in ubiquitin (Ub) conjugases-induced signal by removing Ub from the substrates. Dysregulation ...
A dynamic model of gene activation in response to hypoxia accounting for both HIF-1 and HIF-2 [0.03%]
一个动态的基因激活模型响应低氧环境（包括HIF-1和HIF-2）
Aleksandra Cabaj,Agata Charzyńska,Adrianna Moszyńska et al.
Aleksandra Cabaj et al.
We developed an ordinary differential equations (ODEs) model of hypoxia signaling that, in addition to HIF-1α, takes into account also HIF-2α. Our model can be separated into two parts, the first, describing the production and degradation...
Computational inference of Rhizobium phaseoli transcriptional regulatory network predicts Transcription Factors involved in nodulation [0.03%]
计算推理根瘤菌调控网络预测参与固氮的转录因子
Ericka M Hernandez-Benitez,Esperanza Martínez-Romero,José Luis Aguirre-Noyola et al.
Ericka M Hernandez-Benitez et al.
Growth of the common bean plant Phaseolus vulgaris is tightly linked to its symbiotic relationship with diverse rhizobial species, particularly Rhizobium phaseoli, an alphaproteobacterium that forms root nodules and provides high levels of ...