Using DGGE profiling to develop a novel culture medium suitable for oral microbial communities [0.03%]
利用DGGE文库筛选技术构建新型的人口腔微生物培养基
Y Tian,X He,M Torralba et al.
Y Tian et al.
More than 700 bacterial species have been detected in the human oral cavity. They form highly organized microbial communities and are responsible for many oral infectious diseases, such as dental caries and periodontal disease. The preventi...
Early activation of the interleukin-23-17 axis in a murine model of oropharyngeal candidiasis [0.03%]
毛霉目念珠菌致小鼠口咽念珠菌病模型中白细胞介素-23-17轴的早期活化
J M Saunus,S A Wagner,M A Matias et al.
J M Saunus et al.
Candida albicans is an oral commensal yeast that causes oropharyngeal candidiasis (OPC) in immunocompromised individuals. The immunological pathways involved in OPC have been revisited after the interleukin-17 (IL-17) pathway was implicated...
Characterization of the Streptococcus sobrinus acid-stress response by interspecies microarrays and proteomics [0.03%]
用于检测酸不耐受反应的亲缘芯片和蛋白质组学的技术及其特征符号表征
A R Martinez,J Abranches,J K Kajfasz et al.
A R Martinez et al.
Streptococcus mutans and Streptococcus sobrinus are considered the primary organisms responsible for human dental caries. The ability to generate acids and to adapt to low pH conditions is directly associated with the cariogenic potential o...
Tannerella forsythia infection-induced calvarial bone and soft tissue transcriptional profiles [0.03%]
齿龈密螺旋体感染引起的头骨骨组织和软组织转录谱分析
V Bakthavatchalu,A Meka,S Sathishkumar et al.
V Bakthavatchalu et al.
Tannerella forsythia is associated with subgingival biofilms in adult periodontitis, although the molecular mechanisms contributing to chronic inflammation and loss of periodontal bone remain unclear. We examined changes in the host transcr...
Review: Pathogen-induced inflammation at sites distant from oral infection: bacterial persistence and induction of cell-specific innate immune inflammatory pathways [0.03%]
评论：口腔感染远处部位的病原体诱导性炎症：细菌持续存在和诱导细胞特异性先天免疫炎性通路
C Hayashi,C V Gudino,F C Gibson rd et al.
C Hayashi et al.
A hallmark of infection with the gram-negative pathogen Porphyromonas gingivalis is the induction of a chronic inflammatory response. P. gingivalis induces a local chronic inflammatory response that results in oral inflammatory bone destruc...
Annexin-A1 identified as the oral epithelial cell anti-Candida effector moiety [0.03%]
annexin-a1被鉴定为口腔上皮细胞抗白色念珠菌效应成分
E A Lilly,J Yano,P L Fidel Jr
E A Lilly
Innate and adaptive immunity are considered critical to protection against mucosal candidal infections. Among innate anti-Candida mechanisms, oral and vaginal epithelial cells have antifungal activity. The mechanism is fungistatic, acid-lab...
Adaptive immune response in osteoclastic bone resorption induced by orally administered Aggregatibacter actinomycetemcomitans in a rat model of periodontal disease [0.03%]
牙龈炎大鼠模型中牙周病发病过程中Aggregatibacter actinomycetemcomitans诱导破骨性骨吸收的适应性免疫反应
Y Li,C Messina,M Bendaoud et al.
Y Li et al.
There is mounting evidence that innate and adaptive immunity are critical for periodontal disease-mediated bone resorption. These studies examined the role of B and CD4 T cells in adaptive immunity of rats infected with Aggregatibacter acti...
Molecular characterization of Treponema denticola infection-induced bone and soft tissue transcriptional profiles [0.03%]
齿密螺旋体感染诱导的骨和软组织转录图谱的分子表征
V Bakthavatchalu,A Meka,S Sathishkumar et al.
V Bakthavatchalu et al.
Treponema denticola is associated with subgingival biofilms in adult periodontitis and with acute necrotizing ulcerative gingivitis. However, the molecular mechanisms by which T. denticola impacts periodontal inflammation and alveolar bone ...
S D Riewe,J J Mans,T Hirano et al.
S D Riewe et al.
Porphyromonas gingivalis is a periodontal pathogen that is also associated with preterm low-birthweight delivery. We investigated the transcriptional responses of human extravillous trophoblasts (HTR-8) to infection with P. gingivalis. Over...
The Hpk2-Rrp2 two-component regulatory system of Treponema denticola: a potential regulator of environmental and adaptive responses [0.03%]
齿密螺旋体中的Hpk2-Rrp2双组分调控系统：环境及适应性响应的潜在调节因子
J Sarkar,J Frederick,R T Marconi
J Sarkar
Treponema denticola levels in the gingival crevice become elevated as periodontal disease develops. Oral treponemes may account for as much as 40% of the total bacterial population in the periodontal pocket. The stimuli that trigger enhance...