VimA-dependent modulation of the secretome in Porphyromonas gingivalis [0.03%]
牙龈卟啉单胞菌中VimA依赖性的分泌组调节机制研究
D Osbourne,A Wilson Aruni,Y Dou et al.
D Osbourne et al.
The VimA protein of Porphyromonas gingivalis is a multifunctional protein involved in cell surface biogenesis. To further determine if its acetyl coenzyme A (acetyl-CoA) transfer and putative sorting functions can affect the secretome, its ...
Comparative Study
Molecular oral microbiology. 2012 Dec;27(6):420-35. DOI:10.1111/j.2041-1014.2012.00661.x 2012
Beyond the red complex and into more complexity: the polymicrobial synergy and dysbiosis (PSD) model of periodontal disease etiology [0.03%]
超越红 complexes：牙周病病因的多微生物协同和微生态失衡(PSD)模型
G Hajishengallis,R J Lamont
G Hajishengallis
Recent advancements in the periodontal research field are consistent with a new model of pathogenesis according to which periodontitis is initiated by a synergistic and dysbiotic microbial community rather than by select 'periopathogens', s...
Sustained mitogen-activated protein kinase activation with Aggregatibacter actinomycetemcomitans causes inflammatory bone loss [0.03%]
牙龈密螺旋体持续激活MAPK可引起炎性骨破坏
J Dunmyer,B Herbert,Q Li et al.
J Dunmyer et al.
Aggregatibacter actinomycetemcomitans is a gram-negative facultative capnophile involved in pathogenesis of aggressive forms of periodontal disease. In the present study, we interrogated the ability of A. actinomycetemcomitans to stimulate ...
Comparative Study
Molecular oral microbiology. 2012 Oct;27(5):397-407. DOI:10.1111/j.2041-1014.2012.00656.x 2012
Characterization of the secretion pathway of the collagen adhesin EmaA of Aggregatibacter actinomycetemcomitans [0.03%]
牙龈卟啉单胞菌胶原蛋白粘附素EmaA分泌途径的特征研究
X Jiang,T Ruiz,K P Mintz
X Jiang
The extracellular matrix protein adhesin A (EmaA) surface antennae-like structures of the periodontal pathogen Aggregatibacter actinomycetemcomitans are composed of three identical protein monomers. Recently, we have demonstrated that the p...
Toll-like receptor 4 mediates intrauterine growth restriction after systemic Campylobacter rectus infection in mice [0.03%]
全身感染牙龈卟啉单胞菌后， toll 样受体 4介导小鼠宫内生长受限
R M Arce,K M Caron,S P Barros et al.
R M Arce et al.
Campylobacter rectus is associated with fetal exposure and low birthweight in humans. C. rectus also invades placental tissues and induces fetal intrauterine growth restriction (IUGR) in mice, along with overexpression of Toll-like receptor...
Comparative Study
Molecular oral microbiology. 2012 Oct;27(5):373-81. DOI:10.1111/j.2041-1014.2012.00651.x 2012
Salivary proteins promote proteolytic activity in Streptococcus mitis biovar 2 and Streptococcus mutans [0.03%]
唾液蛋白促进口腔链球菌属生物变种的蛋白水解活性
C Kindblom,J R Davies,M C Herzberg et al.
C Kindblom et al.
A major function of the salivary pellicle on oral surfaces is to promote colonization of the commensal microbiota by providing binding sites for adherence. Streptococcus mitis is an early colonizer of the oral cavity whereas Streptococcus m...
Comparative Study
Molecular oral microbiology. 2012 Oct;27(5):362-72. DOI:10.1111/j.2041-1014.2012.00650.x 2012
Molecular approaches for viable bacterial population and transcriptional analyses in a rodent model of dental caries [0.03%]
分子方法在啮齿动物牙釉质脱矿模型中检测菌斑细菌及转录分析
M I Klein,K M Scott-Anne,S Gregoire et al.
M I Klein et al.
Culturing methods are the primary approach for microbiological analysis of plaque biofilms in rodent models of dental caries. In this study, we developed strategies for the isolation of DNA and RNA from plaque biofilms formed in vivo to ana...
Novel iron-regulated and Fur-regulated small regulatory RNAs in Aggregatibacter actinomycetemcomitans [0.03%]
牙龈卟啉单胞菌中铁调控的小分子调节RNA的鉴定及其功能研究
J J Amarasinghe,T D Connell,F A Scannapieco et al.
J J Amarasinghe et al.
Iron can regulate biofilm formation via non-coding small RNA (sRNA). To determine if iron-regulated sRNAs are involved in biofilm formation by the periodontopathogen Aggregatibacter actinomycetemcomitans, total RNA was isolated from bacteri...
Identification and characterization of a collagen-binding protein, Cbm, in Streptococcus mutans [0.03%]
变异链球菌胶原结合蛋白Cbm的鉴定及特性分析
R Nomura,K Nakano,S Naka et al.
R Nomura et al.
Streptococcus mutans, a major pathogen of dental caries, is occasionally isolated from the blood of patients with infective endocarditis. Bacterial attachment of exposed collagen tissue in the impaired endothelium is an important step in th...
Streptococcus oralis coaggregation receptor polysaccharides induce inflammatory responses in human aortic endothelial cells [0.03%]
口腔链球菌聚集受体多糖诱导人主动脉内皮细胞的炎症反应
A de Toledo,E Nagata,Y Yoshida et al.
A de Toledo et al.
Streptococcus oralis, belonging to the oral viridans group streptococci, has been detected in human cardiovascular lesions including infective endocarditis and atheromatous plaques. The organism has coaggregation receptor polysaccharides (R...