Comparative genotyping of Streptococcus mutans by repetitive extragenic palindromic polymerase chain reaction and multilocus sequence typing [0.03%]
重复回文序列聚合酶链反应和多重序列分型法对变异链球菌的基因分型比较研究
S S Momeni,J Whiddon,S A Moser et al.
S S Momeni et al.
The genetic diversity of Streptococcus mutans has been extensively studied using a variety of genotyping methods. Repetitive extragenic palindromic-polymerase chain reaction (rep-PCR) is a genotyping approach used for screening large number...
Comparative Study
Molecular oral microbiology. 2013 Feb;28(1):18-27. DOI:10.1111/omi.12002 2013
Alpha-amylase is a human salivary protein with affinity to lipopolysaccharide of Aggregatibacter actinomycetemcomitans [0.03%]
人唾液淀粉酶与牙龈卟啉单胞菌脂多糖的亲和力研究
J E Baik,S W Hong,S Choi et al.
J E Baik et al.
Aggregatibacter actinomycetemcomitans lipopolysaccharide (Aa.LPS) is a major virulence factor associated with aggressive periodontitis. Although the recognition of Aa.LPS is potentially initiated by salivary proteins in the oral cavity, Aa....
Nuclear factor-κB and p38 mitogen-activated protein kinase signaling pathways are critically involved in Porphyromonas gingivalis lipopolysaccharide induction of lipopolysaccharide-binding protein expression in human oral keratinocytes [0.03%]
牙龈卟啉单胞菌脂多糖诱导人口腔角质细胞脂多糖结合蛋白表达的核因子-κB和p38丝裂原活化蛋白激酶信号途径的参与作用
P-H Ding,C-Y Wang,R P Darveau et al.
P-H Ding et al.
Lipopolysaccharide (LPS) -binding protein (LBP) plays a crucial role in innate host response to bacterial challenge. Porphyromonas gingivalis is a keystone pathogen in periodontal disease and the shift of P. gingivalis LPS lipid A structure...
A novel phosphotransferase system of Streptococcus mutans is responsible for transport of carbohydrates with α-1,3 linkage [0.03%]
乳链球菌中一种新颖的磷酸转移系统可运输具有α-1,3连接的糖类
D Ajdic,Z Chen
D Ajdic
The most common type of carbohydrate-transport system in Streptococcus mutans is the phosphoenolpyruvate-sugar phosphotransferase system (PTS). Fourteen PTS exist in S. mutans UA159. Several studies have shown that microorganisms growing in...
Neutrophils alter epithelial response to Porphyromonas gingivalis in a gingival crevice model [0.03%]
中性粒细胞改变牙龈隐窝模型中牙龈卟啉单胞菌的上皮反应
J L Bondy-Carey,J Galicia,J Bagaitkar et al.
J L Bondy-Carey et al.
A gingival crevice model (epithelial cell-Porphyromonas gingivalis-neutrophil) was established and used to profile gingipain, matrix metalloproteinase (MMP), MMP mediators [neutrophil gelatinase-associated lipocalin (NGAL) and tissue inhibi...
Divergence of the systemic immune response following oral infection with distinct strains of Porphyromonas gingivalis [0.03%]
不同牙龈卟啉单胞菌株引起的不同全身免疫反应
J T Marchesan,T Morelli,S K Lundy et al.
J T Marchesan et al.
Periodontitis is a polymicrobial oral infection characterized by the destruction of tooth-supporting structures that can be linked to systemic diseases such as cardiovascular disease, diabetes or rheumatoid arthritis. Porphyromonas gingival...
The fate of Treponema denticola within human gingival epithelial cells [0.03%]
Treponema denticola 在人牙龈上皮细胞内的命运
J Shin,Y Choi
J Shin
Treponema denticola is one of the major pathogens associated with chronic periodontitis. Bacterial invasion into gingival tissues is a critical process in the pathogenesis of periodontal disease. We recently reported that T. denticola can i...
Identification and characterization of novel glycoproteins involved in growth and biofilm formation by Porphyromonas gingivalis [0.03%]
齿龈密螺旋体生长及生物被膜形成的新糖蛋白的鉴定和表征
M Kishi,Y Hasegawa,K Nagano et al.
M Kishi et al.
Porphyromonas gingivalis has been implicated as a major pathogen associated with chronic periodontitis. To extend our knowledge of post-translational protein glycosylation in P. gingivalis, a proteomic analysis involving two-dimensional pol...
Inhibition of Porphyromonas gingivalis-induced periodontal bone loss by CXCR4 antagonist treatment [0.03%]
CXCR4拮抗剂治疗可抑制牙龈卟啉单胞菌诱导的牙槽骨丧失
M L McIntosh,G Hajishengallis
M L McIntosh
Microbial pathogens have evolved mechanisms to proactively manipulate innate immunity, thereby improving their fitness in mammalian hosts. We have previously shown that Porphyromonas gingivalis exploits CXC-chemokine receptor-4 (CXCR4) to i...
C Cunha Villar,J Chukwuedum Aniemeke,X-R Zhao et al.
C Cunha Villar et al.
During infection, interactions between Candida albicans and oral epithelial cells result in oral epithelial cell death. This is clinically manifested by the development of oral mucosal ulcerations generally associated with discomfort. In vi...