Sequence divergence in the Treponema denticola FhbB protein and its impact on factor H binding [0.03%]
Treponema denticola FhbB蛋白的序列分歧及其对结合因子H的影响
D P Miller,J V McDowell,D V Rhodes et al.
D P Miller et al.
Treponema denticola is an anaerobic spirochete whose abundance in the subgingival crevice correlates with the development and severity of periodontal disease. The ability of T. denticola to survive and thrive in the hostile environment of t...
Comparative Study
Molecular oral microbiology. 2013 Aug;28(4):316-30. DOI:10.1111/omi.12027 2013
Identification of β-haemolysin-encoding genes in Streptococcus anginosus [0.03%]
溶血性链球菌中编码β-溶血素基因的鉴定
D Asam,S Mauerer,E Walheim et al.
D Asam et al.
Streptococcus anginosus is an emerging pathogen, but little is known about its virulence factors. To detect the genes responsible for β-haemolysis we performed genomic mutagenesis of the β-haemolytic S. anginosus type strain ATCC 12395 us...
Comparative Study
Molecular oral microbiology. 2013 Aug;28(4):302-15. DOI:10.1111/omi.12026 2013
Fermentative 2-carbon metabolism produces carcinogenic levels of acetaldehyde in Candida albicans [0.03%]
卡波氏肉瘤病毒通过发酵型的二碳代谢产生致癌性乙醛
E Marttila,P Bowyer,D Sanglard et al.
E Marttila et al.
Acetaldehyde is a carcinogenic product of alcohol fermentation and metabolism in microbes associated with cancers of the upper digestive tract. In yeast acetaldehyde is a by-product of the pyruvate bypass that converts pyruvate into acetyl-...
A galactose-specific sugar: phosphotransferase permease is prevalent in the non-core genome of Streptococcus mutans [0.03%]
一种专性半乳糖磷酸转移酶渗入酶是非核心基因组中变异链球菌中存在的普遍现象
L Zeng,P Xue,M J Stanhope et al.
L Zeng et al.
Three genes predicted to encode the A, B and C domains of a sugar : phosphotransferase system (PTS) permease specific for galactose/(EII(Gal) ) were identified in the genomes of 35 of 57 recently sequenced isolates of Streptococcus mutans, ...
Toll-like receptor 2-mediated modulation of growth and functions of regulatory T cells by oral streptococci [0.03%]
口腔链球菌通过 toll 样受体 2 调节调节性 T 细胞的生长和功能
A Saeki,T Segawa,T Abe et al.
A Saeki et al.
This study was designed to determine whether oral streptococci modulate the growth and functions of regulatory T cells. Heat-killed cells of wild-type strains of Streptococcus gordonii and Streptococcus mutans induced the Toll-like receptor...
Differential interactions of Streptococcus gordonii and Staphylococcus aureus with cultured osteoblasts [0.03%]
牙囊细胞培养中金黄色葡萄球菌和戈登链球菌对骨形成细胞的相互作用差异性研究
C E Jauregui,J P Mansell,M A Jepson et al.
C E Jauregui et al.
The impedance of normal osteoblast function by microorganisms is at least in part responsible for the failure of dental or orthopedic implants. Staphylococcus aureus is a major pathogen of bone, and exhibits high levels of adhesion and inva...
Characteristics of Porphyromonas gingivalis lipopolysaccharide in co-culture with Fusobacterium nucleatum [0.03%]
与核梭杆菌共培养的牙龈卟啉单胞菌脂多糖的特性
S H Lee,D H Baek
S H Lee
Porphyromonas gingivalis is associated with chronic periodontitis and forms multi-species biofilms. They can communicate within species as well as with other species found in the subgingiva, which may induce changes in the growth ratio and ...
Evidence of mutualism between two periodontal pathogens: co-operative haem acquisition by the HmuY haemophore of Porphyromonas gingivalis and the cysteine protease interpain A (InpA) of Prevotella intermedia [0.03%]
牙周病原菌互惠的证据:具核梭杆菌的细胞外血红素结合蛋白HmuY与中间普氏菌的半胱氨酸蛋白酶Interpain A(InpA)协同获取血红素
D P Byrne,J Potempa,T Olczak et al.
D P Byrne et al.
Haem (iron protoporphyrin IX) is both an essential growth factor and a virulence regulator of the periodontal pathogens Porphyromonas gingivalis and Prevotella intermedia, which acquire it through the proteolytic degradation of haemoglobin ...
Mechanism and implications of CXCR4-mediated integrin activation by Porphyromonas gingivalis [0.03%]
牙龈卟啉单胞菌通过CXCR4介导的整合素活化机制及其意义
G Hajishengallis,M L McIntosh,S-I Nishiyama et al.
G Hajishengallis et al.
In monocytes and macrophages, the interaction of Porphyromonas gingivalis with Toll-like receptor 2 (TLR2) leads to the activation of a MyD88-dependent antimicrobial pathway and a phosphatidylinositol-3 kinase (PI3K) -dependent pro-adhesive...
VimA mediates multiple functions that control virulence in Porphyromonas gingivalis [0.03%]
VimA调控牙龈卟啉单胞菌毒力的多种功能
A W Aruni,A Robles,H M Fletcher
A W Aruni
Porphyromonas gingivalis, a black-pigmented, gram-negative anaerobe, is an important etiological agent of periodontal disease. Its ability to survive in the periodontal pocket and orchestrate the microbial/host activities that can lead to d...