Energy and metabolism [0.03%]
能量与代谢
Raul K Suarez
Raul K Suarez
Although firmly grounded in metabolic biochemistry, the study of energy metabolism has gone well beyond this discipline and become integrative and comparative as well as ecological and evolutionary in scope. At the cellular level, ATP is hy...
James D Stockand,Volker Vallon,Pablo Ortiz
James D Stockand
Analysis of tubule function with in vivo and ex vivo approaches has been instrumental in revealing renal physiology. This work allows assignment of functional significance to known gene products expressed along the nephron, primary of which...
Chronic blood pressure control [0.03%]
慢性血压控制
Michael W Brands
Michael W Brands
Chronic blood pressure is maintained within very narrow limits around an average value. However, the multitude of physiologic processes that participate in blood pressure control present a bewildering array of possibilities to explain how s...
Greg S Martin,Kenneth L Brigham
Greg S Martin
Acute lung injury (ALI) and its most severe form, acute respiratory distress syndrome (ARDS), were presciently described nearly two centuries ago by René Laennec, later to be described clinically in the 1950s and 1960s. Substantial advance...
Mathias Dutschmann,Thomas E Dick
Mathias Dutschmann
Pontine respiratory nuclei provide synaptic input to medullary rhythmogenic circuits to shape and adapt the breathing pattern. An understanding of this statement depends on appreciating breathing as a behavior, rather than a stereotypic rhy...
John E Hall,Joey P Granger,Jussara M do Carmo et al.
John E Hall et al.
Despite major advances in understanding the pathophysiology of hypertension and availability of effective and safe antihypertensive drugs, suboptimal blood pressure (BP) control is still the most important risk factor for cardiovascular mor...
Cell migration [0.03%]
细胞迁移
Xavier Trepat,Zaozao Chen,Ken Jacobson
Xavier Trepat
Cell migration is fundamental to establishing and maintaining the proper organization of multicellular organisms. Morphogenesis can be viewed as a consequence, in part, of cell locomotion, from large-scale migrations of epithelial sheets du...
Eckehard A E Stuth,Astrid G Stucke,Edward J Zuperku
Eckehard A E Stuth
This article provides a comprehensive, up to date summary of the effects of volatile, gaseous, and intravenous anesthetics and opioid agonists on ventilatory control. Emphasis is placed on data from human studies. Further mechanistic insigh...
Computational models and emergent properties of respiratory neural networks [0.03%]
呼吸神经网络的计算模型及其涌现特性研究进展
Bruce G Lindsey,Ilya A Rybak,Jeffrey C Smith
Bruce G Lindsey
Computational models of the neural control system for breathing in mammals provide a theoretical and computational framework bringing together experimental data obtained from different animal preparations under various experimental conditio...
Mary I Townsley
Mary I Townsley
The pulmonary vasculature comprises three anatomic compartments connected in series: the arterial tree, an extensive capillary bed, and the venular tree. Although, in general, this vasculature is thin-walled, structure is nonetheless comple...