ADNP missense variant p.C687R disrupts chromatin regulation and GABAergic differentiation in Helsmoortel-Van der Aa syndrome [0.03%]
ADNP错义突变p.cys687arg通过干扰染色质调节和Helsmoortel-Van der Aa综合征中的GABA能分化导致疾病发生发展
Qi Chen,Xixi Liu,Mengnan Wu et al.
Qi Chen et al.
Background: Activity-dependent neuroprotective protein (ADNP) is a critical regulator of neurodevelopment, and most pathogenic variants reported in Helsmoortel–Van der Aa syndrome (HVDAS) are truncating variants. In cont...
Increased c-Fos expression in lateral habenula during social transmission of negative valence in prairie voles [0.03%]
草原田鼠在负面情绪的社会传递过程中侧缰核c-Fos表达增加
Daniella Gamboa Pabón,Jolee Hatfield-King,Shivangi Patel et al.
Daniella Gamboa Pabón et al.
Background: Social learning is the process of acquiring social skills, new information, or associating negative or positive valence to a context through the observation of others and through direct social interaction with...
Reduced task adaptation and contextual awareness in autistic adults during facial emotion recognition: evidence from mixed-effects modeling and automated facial analysis [0.03%]
自闭症成人面部情绪识别过程中的任务适应减退和情境意识缺失：来自混合效应建模和自动面部分析的证据
Simon Kirsch,Hanna Drimalla,William Saakyan et al.
Simon Kirsch et al.
Biased mental face representations of autistic children in the general population [0.03%]
普通人群中自闭症儿童的偏倚化面部表征
Qiandong Wang,Waxun Su,Liting Zeng et al.
Qiandong Wang et al.
Large-scale neural network compensation associated with camouflaging in trait autism and its potential mental health costs [0.03%]
与自闭症特征掩饰相关的大型神经网络补偿及其潜在的精神健康成本
Han Guo,Xiaobing Chen,Aihua Zhou et al.
Han Guo et al.
Siti Nurnadhirah Binte Mohd Ikhsan,Rosemary Holt,Amber Ruigrok et al.
Siti Nurnadhirah Binte Mohd Ikhsan et al.
Background: Despite rising rates of autism prevalence, there remains a pressing need to enhance the quality of life for autistic people in Europe and around the world. ...
Association of glymphatic dysfunction, free water, white matter integrity and long-term memory performance in aging autistic adults [0.03%]
老年自闭症患者糖淋巴系统功能障碍、自由水、白质完整性和长期记忆表现之间的关联研究
Yuanchao Zhang,Edward Ofori,Kewei Chen et al.
Yuanchao Zhang et al.
Background: Autistic adults are at elevated risk of accelerated cognitive aging and Alzheimer’s disease and related dementias (ADRD), yet the underlying neurobiological mechanisms remain poorly understood. Dysfunction in...
Reduced inter-subject functional connectivity during movies in autism: replicability across cross-national fMRI datasets [0.03%]
利用跨国磁共振数据集验证自闭症患者观看电影时的功能连接减小现象
Feng Lin,Laura Albantakis,Tuomo Noppari et al.
Feng Lin et al.
Background: Autism is a neurodevelopmental disorder characterized by repetitive behaviors and difficulties in social communication and interaction. Previous research has shown that these symptoms are linked to idiosyncrat...
Cholecystokinin upregulation in mPFC leads to social defeat-induced anxiety susceptibility in neuroligin 3 R451C knockin mice [0.03%]
神经粘着蛋白3 R451C敲入小鼠社会挫败引起的焦虑易感性与mPFC胆囊收缩素上调有关
Yuzhen Fu,Yuke Xu,Huiyi Li et al.
Yuzhen Fu et al.
Cerebellar purkinje cell dysfunction contributes to gait impairments in Shank3-mutant mice [0.03%]
突触蛋白3基因突变小鼠小脑浦肯野细胞功能障碍导致运动缺陷
Haiying Liu,Xin Huang,Guaiguai Ma et al.
Haiying Liu et al.