RVX-208, an inducer of Apolipoprotein A-I, inhibits the particle production of hepatitis B virus through activation of cGAS-STING pathway [0.03%]
RVX-208通过激活cGAS-STING途径抑制乙肝病毒颗粒产生
Dan Shu,Lin Cheng,Kefei Yuan et al.
Dan Shu et al.
Background: Previously, we have demonstrated that Apolipoprotein A-I (ApoA-I) could inhibit the secretion of Hepatitis B virus (HBV), suggesting that stimulation of ApoA-I may block particle production. In the present stu...
Waitlist-controlled trial of an online intervention to address mental health among older people living with HIV [0.03%]
一项针对HIV阳性老年人在线干预以解决精神健康问题的等候名单控制试验
Jeff Berko,Peter Mazonson,Duncan Short et al.
Jeff Berko et al.
Background: Older people living with HIV (PLWH) often experience elevated levels of depression, anxiety, and loneliness.Methods: This waitlist-controlled trial examined the effectiveness of online audio mindfulness lessons in impacting thes...
Randomized Controlled Trial
Antiviral therapy. 2023 Dec;28(6):13596535231216311. DOI:10.1177/13596535231216311 2023
Subacute thyroiditis following COVID-19 vaccination: Case presentation [0.03%]
新型冠状病毒疫苗接种后发生的亚急性甲状腺炎：病例报告
Aleksandra Z Tomic,Sonja S Zafirovic,Zoran M Gluvic et al.
Aleksandra Z Tomic et al.
Background: Subacute thyroiditis (SAT) is an organ-specific disease that various drugs, including COVID-19 vaccines, can trigger. COVID-19 infection has been associated with thyroid gland damage and disease SARS-CoV-2 direct action, euthyro...
Andrographolide inhibits infectious bronchitis virus-induced apoptosis, pyroptosis, and inflammation [0.03%]
安卡化合物通过抑制凋亡、焦亡和炎症来对抗禽流感病毒感染呼吸道上皮细胞的作用研究
Jiachen Shen,Qiuchi Xu,Lu Chen et al.
Jiachen Shen et al.
Background: Avian infectious bronchitis virus (IBV), a coronavirus, causes a huge economic loss to the poultry industry. Andrographolide (APL) is a compound with a variety of pharmacological properties, including antivira...
HIV drug resistance in the era of contemporary antiretroviral therapy: A clinical perspective [0.03%]
当代抗逆转录病毒疗法时代的 HIV 药物耐药性：临床视角
Andrew Carr,Nicola E Mackie,Roger Paredes et al.
Andrew Carr et al.
Contemporary antiretroviral therapy (ART) regimens have high barriers to the development of drug resistance. However, resistance to earlier antiretrovirals and uncommon cases of resistance to contemporary ART illustrate the continued need f...
Computer-assisted drug discovery of potential natural inhibitors of the SARS-CoV-2 RNA-dependent RNA polymerase through a multi-phase in silico approach [0.03%]
基于计算机辅助的抗SARS-CoV-2复制酶活性天然产物抑制剂的虚拟筛选与发现
Eslam B Elkaeed,Bshra A Alsfouk,Tuqa H Ibrahim et al.
Eslam B Elkaeed et al.
Background: The COVID-19 pandemic has led to significant loss of life and economic disruption worldwide. Currently, there are limited effective treatments available for this disease. SARS-CoV-2 RNA-dependent RNA polymeras...
Retrospective chart review of transplant recipients with cytomegalovirus infection who received maribavir in the Phase 3 SOLSTICE trial: Data at 52 weeks post-maribavir treatment initiation [0.03%]
III期SOLSTICE试验中接受马里巴韦治疗的巨细胞病毒感染移植受者患者的回顾性图表审查：为期52周的随访数据.post-马里巴韦治疗启动
Marielle Bassel,Dorothy Romanus,Tien Bo et al.
Marielle Bassel et al.
Background: Cytomegalovirus (CMV) infection is a frequent complication in haematopoietic cell/solid organ transplant (HCT/SOT) recipients. Previous studies report all-cause mortality rates of 31% and 50% in HCT/SOT recipi...
Hepatitis C virus/Hepatitis B virus coinfection: Current prospectives [0.03%]
丙型肝炎病毒/乙型肝炎病毒合并感染：当前展望
Quratulain Maqsood,Aleena Sumrin,Maryam Iqbal et al.
Quratulain Maqsood et al.
In endemic areas, hepatitis C virus (HCV)/hepatitis B virus (HBV) coinfection is common, and patients with coinfection have a higher risk of developing liver disease such as hepatocellular carcinoma, liver fibrosis and cirrhosis. In such ca...
Letter to the editor on use of antibodies from convalescent sera in the treatment of moderate and severe Covid-19 infection [0.03%]
致编辑关于使用康复血清中的抗体治疗中重症新冠肺炎感染的信
Sarah B Nahhal,Bassem Awada,Joe-David Azzo et al.
Sarah B Nahhal et al.
Fanconi syndrome, diabetes insipidus, and acute kidney injury due to tenofovir disoproxil fumarate: A case report [0.03%]
富马酸替诺福韦二吡呋酯导致范可尼综合征、尿崩症和急性肾损伤的病例报告
Nthabiseng Zilwa,Onalethata Mpejane,Golam Mehboob et al.
Nthabiseng Zilwa et al.
Background: Tenofovir disoproxil fumarate is widely used in Botswana as part of the first-line antiretroviral regimen in the 'Treat All' strategy implemented in 2016 by the Ministry of Health. Its use has been associated ...