Seroprevalence, seroconversion, and mother-to-child transmission of dual and triplex infections of HIV, HBV, and HCV among Nigerian obstetric population: A national multicentre prospective cohort study [0.03%]
尼日利亚妇产科人群HIV、HBV和HCV双重和三重感染的血清流行率、血清转化及母婴传播：一项全国多中心前瞻性队列研究
George Uchenna Eleje,Hadiza Abdullahi Usman,Chinyere Ukamaka Onubogu et al.
George Uchenna Eleje et al.
ObjectivesTo determine seroprevalence, seroconversion, and mother-to-child transmission (MTCT) rates for dual and triplex infections of human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV) among pregnant ...
Multicenter Study
Antiviral therapy. 2025 Apr;30(2):13596535251333259. DOI:10.1177/13596535251333259 2025
Sustained viral suppression with once daily dolutegravir-containing regimen in presence of the strong inducer carbamazepine [0.03%]
卡马西平诱导情况下每日一次含多替拉韦方案能持续抑制病毒拷贝数
Micol Pallanza,Paul Thoueille,Myriam Briki et al.
Micol Pallanza et al.
Dolutegravir 50 mg twice daily (BID) dosing is currently recommended in presence of strong inducers of drug metabolism. However, this dosing has been challenged by studies showing similar rates of viral suppression with dolutegravir once da...
Durability of multi-drug antiretroviral therapy (mega-ART) in treatment-experienced people with HIV in the ARCA database [0.03%]
ARCA数据库中经治HIV感染者的多药抗逆转录病毒疗法（ mega-ART）的持久性
Laura Labate,Barbara Rossetti,Chiara Russo et al.
Laura Labate et al.
ObjectiveTo explore the durability of multi-drug antiretroviral regimens in treatment-experienced PWH.DesignThis retrospective observational study including PWH who started mega-ART regimens between 1 January 2009 and 31 December 2019, sele...
Observational Study
Antiviral therapy. 2025 Apr;30(2):13596535251317054. DOI:10.1177/13596535251317054 2025
Functional foods and immune system: A sustainable inhibitory approach against SARS-COV-2 [0.03%]
功能性食品与免疫系统：对抗SARS-COV-2的可持续抑制方法
Hubza Ruatt Khan,Rabia Sultan,Mehvish Javeed et al.
Hubza Ruatt Khan et al.
Background: COVID-19 has become the center of attention since its outbreak in December 2019. Despite the discovery of its preventive vaccine, role of healthy immune system is undebatable. Functional foods are continuously hunted as a promis...
Nathan Sudeep,Noah Kojima,Jeffrey D Klausner
Nathan Sudeep
Background: Nirmatrelvir has been shown to reduce morbidity and mortality associated with COVID-19. However, it is underutilized due to concerns regarding COVID-19 symptom rebound following nirmatrelvir's standard 5-day c...
Increased insulin resistance following switch from efavirenz to cobicistat-boosted elvitegravir [0.03%]
从依非韦伦换用依法韦仑/科比司他后胰岛素抵抗增强
Richard Taylor Pickering,Archana Asundi,Alex Olson et al.
Richard Taylor Pickering et al.
Background: Integrase strand transfer inhibitors (INSTIs) have been associated with excess weight gain in people living with HIV compared to other antiretroviral agents. The mechanisms that underlie these effects are not ...
Clinical outcomes among COVID-19 patients initiated on molnupiravir in Denmark - A national registry study [0.03%]
丹麦莫努匹韦治疗新冠肺炎患者的临床结局——一项全国登记队列研究
Carsten S Larsen,Caroline L Westergaard,Nina B Stærke et al.
Carsten S Larsen et al.
Background: Molnupiravir (MOV) is an orally bioavailable ribonucleoside with antiviral activity against all tested SARS-CoV-2 variants. We describe the demographic, clinical, and treatment characteristics of non-hospitali...
Effectiveness of bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) as switch strategy in virologically-suppressed patients: real world data from a monocentric cohort [0.03%]
伏立伟抑制剂/恩曲他滨/特诺福韦艾拉酚胺(BIC/FTC/TAF)换药策略对病毒学抑制患者的疗效：单一中心队列的现实世界数据
R A Passerotto,F Lamanna,P F Salvo et al.
R A Passerotto et al.
Introduction: BIC/FTC/TAF showed efficacy and tolerability in randomized trials as a switch strategy in virologically-suppressed people living with HIV. We evaluated its effectiveness in a real-life setting. ...
Repurposing FDA-approved drugs for COVID-19: targeting the main protease through multi-phase in silico approach [0.03%]
基于多阶段计算机模拟的新冠肺炎康复计划：针对主要蛋白酶的FDA批准药物再定位研究
Ahmed M Metwaly,Eslam B Elkaeed,Aisha A Alsfouk et al.
Ahmed M Metwaly et al.
Background: The COVID-19 pandemic has created an urgent need for effective therapeutic agents. The SARS-CoV-2 Main Protease (Mpro) plays a crucial role in viral replication and immune evasion, making it a key target for d...
Analysis of risk factors and prediction model construction for varicella encephalitis in children: A retrospective cohort study [0.03%]
儿童水痘脑炎风险因素分析及预测模型构建：队列研究
Ce Wang,Li Tang,Dandan Guo
Ce Wang
Introduction: This study aimed to analyze the risk factors for varicella encephalitis in children and establish a predictive model. Methods: ...