Statin effect on coronary calcium distribution, mass and volume scores and associations with immune activation among HIV+ persons on antiretroviral therapy [0.03%]
他汀类药物对HIV感染者在接受逆转录病毒治疗后的冠状钙分布、质量和体积的影响及与免疫激活的相关性研究
Jerry Lipinski,Seunghee Margevicius,Mark D Schluchter et al.
Jerry Lipinski et al.
Background: Inflammation has been associated with whole heart coronary artery calcification (CAC) among people with HIV (PWH) on antiretroviral therapy (ART); however, prior studies have not evaluated the distribution of ...
Randomized Controlled Trial
Antiviral therapy. 2020;25(8):419-427. DOI:10.3851/IMP3389 2020
Treatment modification after second-line failure among people living with HIV in the Asia-Pacific [0.03%]
亚洲太平洋地区艾滋病患者的二线治疗失败后调整治疗方法的状况分析
Awachana Jiamsakul,Iskandar Azwa,Fujie Zhang et al.
Awachana Jiamsakul et al.
Background: The World Health Organization recommends continuation with the failing second-line regimen if third-line option is not available. We investigated treatment outcomes among people living with HIV in Asia who con...
Cytomegalovirus infection associated with severe intraocular inflammation in an HIV patient: a case report [0.03%]
HIV患者巨细胞病毒感染伴严重眼内炎症的病例报告
Viviana P Lezcano Carduz,Nicolás Alejandre Alba,Elena Guzmán Almagro et al.
Viviana P Lezcano Carduz et al.
This is a report of a case of severe intraocular inflammation associated with cytomegalovirus in an untreated HIV+ patient with a marked CD4+ T-cell depletion. The atypical presentation shown could confuse and delay the diagnosis. Early sus...
Case Reports
Antiviral therapy. 2020;25(6):341-344. DOI:10.3851/IMP3381 2020
Effect of vitamin D3 and calcium carbonate supplementation on muscle strength in postmenopausal women living with HIV [0.03%]
维生素D3和碳酸钙补充对生活在艾滋病毒中的绝经后妇女的肌肉力量的影响
Michael T Yin,Mariana Bucovsky,John Williams et al.
Michael T Yin et al.
Background: Both falls and fractures are increased in older persons living with HIV (PLWH). Low serum total 25-hydroxyvitamin D (25-OHD) levels have been associated with falls, fractures and poor muscle strength. We hypot...
Randomized Controlled Trial
Antiviral therapy. 2020;25(8):411-418. DOI:10.3851/IMP3386 2020
Antiviral activity of 1,4-disubstituted-1,2,3-triazoles against HSV-1 in vitro [0.03%]
一类取代的1,2,3-三唑化合物体外抗HSV-1活性研究
Daiane J Viegas,Verônica D da Silva,Camilla D Buarque et al.
Daiane J Viegas et al.
Background: Herpes simplex virus 1 (HSV-1) affects a large part of the adult population. Anti-HSV-1 drugs, such as acyclovir, target thymidine kinase and viral DNA polymerase. However, the emerging of resistance of HSV-1 ...
The protease inhibitor lopinavir, boosted with ritonavir, as treatment for COVID-19: a rapid review [0.03%]
蛋白酶抑制剂洛匹那韦/利托那韦治疗新型冠状病毒肺炎的快速证据回顾
Jienchi Dorward,Oghenekome Gbinigie,Ting Cai et al.
Jienchi Dorward et al.
Background: The HIV protease inhibitor lopinavir, boosted with ritonavir, has been used off-label to treat COVID-19. We aimed to synthesize the clinical evidence for lopinavir/ritonavir as a treatment for COVID-19. ...
Antiviral activity of different extracts of standardized propolis preparations against HSV [0.03%]
标准化蜂胶制品的不同提取物抗HSV病毒活性研究
Sevda Demir,Ali Timucin Atayoglu,Fabio Galeotti et al.
Sevda Demir et al.
Background: Viral infections are among the most common problems in health-care practice. Natural products offer great promise as potentially effective antiviral drugs. Propolis is a honeybee product with biological proper...
How can the latent cytomegalovirus cause an increase in all-cause mortality? An answer based on the microcompetition model [0.03%]
潜伏性人巨细胞病毒导致全因死亡率增加的机制探讨——基于病毒微竞争模型理论
Hanan Polansky
Hanan Polansky
Many studies showed the existence of a positive association between cytomegalovirus (CMV) seropositivity and all-cause mortality. In this paper, we use the microcompetition model to explain how the latent CMV sequesters the limiting GABP∙p...
Saleh A Alqahtani,Maria Buti
Saleh A Alqahtani
The 2019 coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has emerged as a major burden worldwide, resulting in serious public health challenges. HBV infection is another widely spread vi...
Early low-molecular-weight heparin administration is associated with shorter time to SARS-CoV-2 swab negativity [0.03%]
早期给予低分子肝素与缩短新冠病毒核酸检测转阴时间相关
Mattia Trunfio,Elena Salvador,Alberto Gaviraghi et al.
Mattia Trunfio et al.
Background: Antiviral and immune-modulating properties of low-molecular-weight heparin (LMWH) against Coronaviridae have been reported by in vitro studies, but no in vivo evidence is yet available. We sought to know wheth...