Developmental perfluorobutanesulfonic acid (PFBS) exposure alters exocrine pancreas function in zebrafish (Danio rerio) [0.03%]
developmental perfluorobutanesulfonic acid （pfbs）暴露影响斑马鱼（Danio rerio）外分泌胰腺功能
Charlotte Gridley,Kelsey Rodrigues,Isabella Boyack et al.
Charlotte Gridley et al.
Embryonic exposures to perfluorobutanesulfonic acid (PFBS) in zebrafish have been shown to impair pancreas growth. This study investigated the persistence of the truncated pancreas phenotype, functional impacts on digestive enzyme productio...
Developmental perfluorobutanesulfonic acid (PFBS) exposure alters exocrine pancreas function in zebrafish (Danio rerio) [0.03%]
发育期接触全氟丁烷磺酸(PFBS)对斑马鱼（Danio rerio）外分泌胰腺功能的影响
Charlotte Gridley,Kelsey Rodrigues,Isabella Boyack et al.
Charlotte Gridley et al.
Embryonic exposures to perfluorobutanesulfonic acid (PFBS) in zebrafish have been shown to impair pancreas growth. This study investigated the persistence of the truncated pancreas phenotype, functional impacts on digestive enzyme productio...
Linking prenatal exposure to temperature intensity and variability to child mortality: evidence from 31 low-and middle-income countries [0.03%]
温度剧烈变化对低收入和中等收入国家儿童死亡率的影响
Rafi Amir-Ud-Din,Rasheed Ahmed,Fatima Irfan et al.
Rafi Amir-Ud-Din et al.
High child mortality in low-and middle-income countries is compounded by rising temperatures and climate variability. We conducted a retrospective cohort study of singleton live births from DHS birth histories (IPUMS-DHS) linked to gridded ...
The maternal microbiome-epigenome axis in gestational diabetes: pathogenesis, diagnosis, and emerging therapies [0.03%]
妊娠糖尿病下的母体微生态-表观基因轴：发病机制、诊断及新兴疗法
Aliya Abbas Rizvi,Mohammad Abbas,Asma Imran Ansari et al.
Aliya Abbas Rizvi et al.
Gestational diabetes mellitus (GDM) is a common pregnancy complication with profound short- and long-term consequences for both mother and offspring. Beyond transient hyperglycemia, GDM represents a multifactorial metabolic condition shaped...
The Art of Creation: arts-based approaches to translating the Developmental Origins of Health and Disease science for public health impact [0.03%]
从艺术角度解读发育起源健康学说以产生公共卫生影响的艺术创作方法研究
Jordan Chin,Sara Dickinson,Luseadra McKerracher et al.
Jordan Chin et al.
Public understanding of the Developmental Origins of Health and Disease (DOHaD) remains limited, hindering efforts to shift health behaviours and policy. Arts-based knowledge translation (ABKT) offers a promising approach to engage the publ...
Relative fat mass and myopia in adolescents: a cross-sectional study using NHANES data [0.03%]
基于NHANES数据的青少年相对脂肪量与近视的横断面研究
Yan He
Yan He
Adolescence is a peak period for myopia onset, which is closely related to environmental and lifestyle factors. Relative fat mass (RFM), a novel indicator of body fat, provides a more precise measure of adiposity. However, its relationship ...
Maternal high-fat diet impairs pancreatic β-cell development and reduces VAMP-2 levels in islets of mouse offspring [0.03%]
高脂饮食通过降低胰岛VAMP-2水平损害子代小鼠胰岛β细胞的发育
Daniele Correia de Sales,Camila Calvo de Fontes,Adriana Prado Zanella et al.
Daniele Correia de Sales et al.
Maternal nutrition can influence offspring metabolism through metabolic programming, potentially leading to long-term disorders such as obesity and type 2 diabetes. However, the cellular- and tissue-level mechanisms involved in the metaboli...
Developmental origins of ADHD: sex-specific influences of early life unpredictability on symptom profiles [0.03%]
注意缺陷多动障碍的发育起源：生命早期环境不可预测性对男女症状表现的影响不同
Emily C Sweiss,Vanessa Vargas,Curt Sandman et al.
Emily C Sweiss et al.
Exposure to early life adversity (ELA) increases risk of poor mental health outcomes, including attention deficit/hyperactivity disorder (ADHD). In fact, ELA, especially in the form of "household ACEs" (e.g., socioeconomic disadvantage, inc...
The effect of N-acetylcysteine use in high-fat diet-exposed pregnant rats on glucose metabolism and oxidative status in dams and their offspring [0.03%]
N-乙酰半胱氨酸用于高脂饮食暴露妊娠大鼠对其子代糖代谢和氧化应激状态的影响研究
Tugba Tatar,Kıymet Kübra Tüfekci,Musa Tatar
Tugba Tatar
Maternal obesity has been associated with an increased risk of oxidative and metabolic disorders in offspring later in life. This study investigates the therapeutic effects of N-acetylcysteine (NAC), a potent antioxidant, on obesity-induced...
Assessing the influence of preconception paternal nutrition on offspring health: an evidence gap map [0.03%]
评估孕前父亲营养对后代健康影响的证据缺口地图
Maurya Hart,Shreya Saha,Afreen Khan et al.
Maurya Hart et al.
The Developmental Origins of Health and Disease (DOHaD) framework recognizes that preconception exposures influence offspring health, yet paternal nutrition has received little attention compared to maternal diet. To better understand this ...