Low-dose cyantraniliprole alters hepatorenal parameters in pubertal and adult male Wistar rats exposed during pregnancy and lactation [0.03%]
妊娠和哺乳期暴露低剂量氯虫苯甲酰胺对大鼠青春期前后雄性Wistar肝肾参数的影响
Lucas Marcelo Meira Silva,Isadora Chagas Vercellone,Ana Camila Ferreira de Menezes et al.
Lucas Marcelo Meira Silva et al.
Cyantraniliprole is a widely used insecticide that disrupts calcium homeostasis by binding to ryanodine receptors (RyRs) in the sarcoplasmic reticulum. Insects have a type of RyR with a 47% sequence homology to mammalian RyRs. Due to the hi...
Anthropometry to advanced technologies: evaluation of growth and body composition in neonates [0.03%]
从人体测量到先进技术：新生儿生长和身体组成的评估
Cansu Cakici,Eda Koksal
Cansu Cakici
Neonatal growth assessment during the first 28 days of life is a critical determinant of infant health and survival. Anthropometric measurements provide a simple, inexpensive, and non-invasive means to evaluate neonatal size, nutritional st...
Activation of the heat shock response by human milk-derived extracellular vesicles in neonates with perinatal high-fat diet exposure [0.03%]
人类乳汁衍生的细胞外囊泡激活脂肪摄入过多导致的新生儿热休克反应
Jasmyne A Storm,Jueqin Lu,Mon Francis Obtial et al.
Jasmyne A Storm et al.
Maternal consumption of a high-fat diet (mHFD) during perinatal life influences hypothalamic-pituitary-adrenal (HPA) axis activation and impacts the long-term physiological and metabolic health of offspring. Milk-derived extracellular vesic...
Sexual behavior and sexual identity in female offspring of women exposed in utero to diethylstilbestrol (DES) [0.03%]
母体内暴露于己烯雌酚（DES）的女性后代的性行为与性别认同
Rebecca Troisi,Elizabeth E Hatch,Kimberly Bertrand et al.
Rebecca Troisi et al.
Hormone exposure in utero affects male- and female-typical behavior in animals, and these effects may persist in the next generation. Prenatal exposure to diethylstilbestrol (DES), a potent estrogen and endocrine disruptor, has been associa...
Developmental programming of the neonatal period in ruminant livestock: a review [0.03%]
反刍家畜新生期发育程序的回顾性研究
Allison M Meyer
Allison M Meyer
Early life, or the neonatal period, is perhaps the most challenging time for ruminant livestock, as they adapt to the extra-uterine environment, undergo important physiological maturation, and navigate harsh ambient conditions. Maternal inf...
Early prenatal undernutrition leads to metabolic dysfunction-associated steatotic liver disease in a rat model of menopause [0.03%]
孕期早期营养不良可致绝经大鼠代谢功能紊乱相关肝脂肪变性疾病
Tomoko Kimura,Kodai Hino,Minoru Kuroida et al.
Tomoko Kimura et al.
The prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) has increased. MASLD notably increases after menopause in women owing to the drastic reduction in estrogen, which regulates lipid metabolism. While prenatal ...
Peri-conception maternal nutrition and its association with offspring sex: a prospective cohort study using the Japan Environment and Children's Study data [0.03%]
孕前母亲的营养与子女性别的关联：一项使用日本环境与儿童研究数据的前瞻性队列研究
Rie Matsushita,Sachiko Tanaka-Mizuno,Misaki Nakahata et al.
Rie Matsushita et al.
The impact of maternal nutrition during the peri-conception period on offspring sex remains unclear. Therefore, this study aimed to explore the association between maternal nutritional intake around conception and offspring sex. Data were c...
Maternal iron deficiency alters the expression of glucose transporters in offspring [0.03%]
母体缺铁可改变后代葡萄糖转运蛋白的表达
Misaki Furuta,Shunsuke Fujii,Madoka Kumai
Misaki Furuta
Iron deficiency anemia is a major health problem worldwide. Iron is an essential micronutrient in the human body; its demand increases with fetal growth and gestation. Although it has been reported that glucose metabolism is also affected b...
Intrauterine growth restriction promotes hypothalamic circadian dysregulation in adult mouse offspring [0.03%]
宫内生长受限促进小鼠后代成年期下丘脑昼夜节律失调
Alexandra E O&#x;Brien,Peter J Mark,Jeremy T Smith et al.
Alexandra E O&#x;Brien et al.
Adverse prenatal conditions can induce intrauterine growth restriction (IUGR) and increase the risk of adulthood metabolic disease. Mechanisms underlying developmentally programmed metabolic disease remain unclear but may involve disrupted ...
Associations between low birth weight, childhood adversity, and natural disaster with delay discounting among children [0.03%]
儿童低体重、童年创伤及自然灾害经历与即刻折扣的关系研究
Shuhei Terada,Yuto Maeda,Pamela J Surkan et al.
Shuhei Terada et al.
According to the Developmental Origins of Health and Disease (DOHaD) hypothesis, low-birthweight (LBW) infants are programmed to seek additional resources as compensation for early deprivation. However, no study has yet explored this in the...