Effects of esaxerenone add-on therapy versus angiotensin II receptor blocker dose escalation on albuminuria and blood pressure in hypertensive patients with type 2 diabetes: An exploratory randomized study [0.03%]
盐皮质激素受体拮抗剂esorasartan与血管紧张素II受体拮抗剂治疗2型糖尿病肾病患者的降蛋白尿及降压疗效的探索性研究：一项随机对照研究
Makoto Ohara,Takemasa Omachi,Nobuaki Takehana et al.
Makoto Ohara et al.
Aims: Residual albuminuria remains a major clinical challenge in patients with type 2 diabetes mellitus and hypertension despite renin-angiotensin system inhibitor therapy. Esaxerenone, a selective nonsteroidal mineraloco...
Serum-derived microribonucleic acids as potential novel biomarkers for slowly progressive type 1 diabetes mellitus [0.03%]
Ⅰ型成人晚发糖尿病患者血清微小核糖核酸谱系分析及潜在标志物筛查
Hideyuki Okuma,Takahiro Tsutsumi,Masashi Ichijo et al.
Hideyuki Okuma et al.
Objectives: We aimed to identify microribonucleic acids (miRNAs) that could serve as biomarkers for slowly progressive type 1 diabetes mellitus (SPIDDM). ...
Liraglutide reprograms vascular smooth muscle cell metabolism to suppress extracellular matrix remodeling in diabetic atherosclerosis [0.03%]
利拉鲁肽通过重新编程血管平滑肌细胞代谢来抑制糖尿病动脉粥样硬化中外源性基质重塑
Kun Zhu,Hanxiu Liu,Ni He et al.
Kun Zhu et al.
Background: Metabolic reprogramming contributes to vascular dysfunction in diabetic atherosclerosis, but the mechanisms linking hyperglycemia-induced metabolic alterations to extracellular matrix remodeling in vascular sm...
Real-world risk factors and clinical implications of early estimated glomerular filtration rate decline after sodium-glucose cotransporter-2 inhibitor therapy [0.03%]
钠葡萄糖协同转运蛋白-2抑制剂治疗后早期估算肾小球滤过率下降的现实世界风险因素和临床意义
Jangwook Lee,Dayoung Kang,Kyoung-Ah Kim et al.
Jangwook Lee et al.
Aim: To assess the prevalence, risk factors, estimated glomerular filtration rate trajectory, and clinical implications of the early estimated glomerular filtration rate dip after sodium-glucose cotransporter 2 inhibitors...
Takafumi Ojima,Toshimasa Yamauchi
Takafumi Ojima
Recent genomic studies in Asian populations have advanced our understanding of the diagnosis, pathophysiology, risk prediction, and precision care of diabetes. Monogenic diabetes, including maturity-onset diabetes of the young (MODY) and mi...
Alteration of subgingival microbiome in patients with type 2 diabetes induced by diabetes treatment [0.03%]
二甲双胍和吡格列酮对2型糖尿病患者牙周下面微生物群的影响
Moe Inoue,Akito Sakanaka,Naoto Katakami et al.
Moe Inoue et al.
Aims/introduction: Diabetes and periodontal disease, a bacterial infection involving the oral microbiome, have a bidirectional relationship. However, the relationship between poor glycemic control and the oral microbiome ...
The miR-145-5p/NRF2/SLC7A11 axis regulates ferroptosis-mediated renal tubular epithelial cell injury in diabetic nephropathy [0.03%]
miR-145-5p/NRF2/SLC7A11轴调节糖尿病肾病中促进铁死亡的肾小管上皮细胞损伤
Ganlin Wu,Yu Fang,Meirong Xu et al.
Ganlin Wu et al.
Purpose: This study aimed to investigate the molecular mechanism by which the miR-145-5p/NRF2/SLC7A11 axis regulates ferroptosis-mediated renal tubular epithelial cell (RTEC) injury in diabetic nephropathy (DN). ...
Association of glycation gap with hypoglycemia CGM indices, diabetic complications, and quality of life in Japanese type 2 diabetes patients [0.03%]
日本2型糖尿病患者的糖化缺口与动态血糖监测低血糖指标、糖尿病并发症及生活质量的相关性研究
Satomi Sonoda,Yosuke Okada,Tomoya Mita et al.
Satomi Sonoda et al.
Background: The glycation gap (GGap), defined as the discrepancy between glycated hemoglobin (HbA1c) and the value estimated from actual blood glucose level, is associated with diabetic complications, but its association ...
Clinical and psychological effects of the JADEC Diabetes Card System assessed using the Problem Areas in Diabetes (PAID): A retrospective observational study [0.03%]
使用问题糖尿病区域（PAID）评估JADEC糖尿病卡系统的临床和心理影响：回顾性观察研究
Yu Kouchi
Yu Kouchi
Aims/introduction: Diabetes self-management education and support (DSMES) is essential for long-term diabetes care; however, its psychological impact in routine outpatient practice remains unclear. This study evaluated th...
Effects of age, sex, and renal function on bowel movement-improving effects of Bifidobacterium bifidum G9-1 on constipation in patients with type 2 diabetes mellitus and chronic kidney disease: A prespecified subgroup analysis of the BIRDIE study [0.03%]
年龄、性别和肾功能对Bb-G9-1改善2型糖尿病合并慢性肾脏病患者便秘效果的影响：BIRDIE研究的预设亚组分析
Fuki Ikeda,Junko Sato,Hidenori Yoshii et al.
Fuki Ikeda et al.
Introduction: Type 2 diabetes mellitus and chronic kidney disease are associated with increasing risk of constipation. We previously reported that Bifidobacterium bifidum G9-1 improved stool consistency, bowel movement, a...