Sandro Eridani
Sandro Eridani
A linkage between presence of Sickle Haemoglobin (HbS) and protection from malaria infection and clinical manifestations in certain areas was suspected from early observations and progressively elucidated by more recent studies. Research ha...
Translocation t(11;14) (q13;q32) and genomic imbalances in multi-ethnic multiple myeloma patients: a Malaysian study [0.03%]
马来西亚多族裔骨髓瘤患者t(11;14)(q13; q32)易位和基因组不平衡的分析研究
Ivyna Bong Pau Ni,Ng Ching Ching,Chang Kian Meng et al.
Ivyna Bong Pau Ni et al.
More than 50% of myeloma cases have normal karyotypes under conventional cytogenetic analysis due to low mitotic activity and content of plasma cells in the bone marrow. We used a polymerase chain reaction (PCR)-based translocation detectio...
Overexpression of lung resistance-related protein and P-glycoprotein and response to induction chemotherapy in acute myelogenous leukemia [0.03%]
急性髓系白血病中肺耐药相关蛋白和P-糖蛋白过表达与诱导化疗反应的关系研究
Kazue Tsuji,Yan-Hua Wang,Minoko Takanashi et al.
Kazue Tsuji et al.
Lung resistance-related protein (LRP) and P-glycoprotein (P-gp) are associated with multidrug resistance. P-gp overexpression reduces intracellular anticancer drug concentrations and is correlated with low remission rates. However, whether ...
Pure red cell aplasia in a simultaneous pancreas-kidney transplantation patient: inside the erythroblast [0.03%]
胰腺肾联合移植患者纯红细胞再生障碍的病例报告及红系祖细胞体外增殖能力研究
Francesca Labbadia,Eduardo Salido-Fierréz,Juliana Majado-Martinez et al.
Francesca Labbadia et al.
A case of pure red cell aplasia in a simultaneous kidney-pancreas transplant recipient on immunosuppressive therapy is reported here. The patient presented with anemia unresponsive to erythropoietin treatment. Bone marrow cytomorphology was...
Case Reports
Hematology reports. 2012 Jul 11;4(3):e17. DOI:10.4081/hr.2012.e17 2012
Epstein-Barr virus-negative aggressive natural killer-cell leukaemia with high P-glycoprotein activity and phosphorylated extracellular signal-regulated protein kinases 1 and 2 [0.03%]
EB病毒阴性且P-糖蛋白活性高并有丝裂原活化蛋白激酶磷酸化的NK细胞白血病-Larstrom病
Sanja Perkovic,Sandra Basic-Kinda,Vladimir Gasparovic et al.
Sanja Perkovic et al.
Aggressive natural killer-cell leukaemia (ANKL) is a rare type of disease with fulminant course and poor outcome. The disease is more prevalent among Asians than in other ethnic groups and shows strong association with Epstein-Barr virus (E...
Case Reports
Hematology reports. 2012 Jul 11;4(3):e16. DOI:10.4081/hr.2012.e16 2012
B-cell acute lymphoblastic leukemia with t(4;11)(q21;q23) in a young woman: evolution into mixed phenotype acute leukemia with additional chromosomal aberrations in the course of therapy [0.03%]
年轻女性t(4;11)(q21;q23)B细胞急性淋巴细胞白血病:治疗过程中向混合表型急性白血病转化并出现新的染色体异常
Giovanni Carulli,Alessandra Marini,Maria I Ferreri et al.
Giovanni Carulli et al.
About 5% of adult B-cell acute lymphoblastic leukemias (B-ALL) are characterized by t(4;11)(q21;q23), which confers peculiar features to this B-ALL subtype, including a very immature immunophenotype and poor prognosis. We describe the case ...
Case Reports
Hematology reports. 2012 Jul 11;4(3):e15. DOI:10.4081/hr.2012.e15 2012
Combination of cyclophosphamide, etoposide, carboplatin and dexamethasone as a salvage regimen for refractory multiple myeloma patients: a comparison with a historical control group [0.03%]
环磷酰胺、依托泊苷、卡铂和地塞米松联合治疗难治性多发性骨髓瘤:与历史对照组的比较研究
Reza Safaee,Ahmad Ahmadzadeh,Ramezanali Sharifian et al.
Reza Safaee et al.
The aim of this study was to design a regimen for refractory multiple myeloma with minimum complications to achieve a reasonable response. Fifteen patients with active multiple myeloma after at least two lines of conventional treatment unde...
Genotype-phenotype correlation of β-thalassemia spectrum of mutations in an Indian population [0.03%]
印度人群β-地中海贫血谱系突变的基因型表型相关性研究
Praveen Kishore Sahu,Sudhanshu Shekhar Pati,Saroj Kanti Mishra
Praveen Kishore Sahu
Coexistence of thalassemia, hemoglobinopathies and malaria has interested geneticists over many decades. The present study represents such a population from the eastern Indian state of Orissa. Children and their siblings (n=38) were genotyp...
Sanjeev Shyam Rao,Jagdish Prasad Goyal,S V Raghunath et al.
Sanjeev Shyam Rao et al.
The aim of this study was to determine hematological profile of sickle cell disease (SCD) from Surat, South Gujarat, India. This prospective cross-sectional study was conducted in the Department of Pediatrics and Sickle Cell Anemia Laborato...
Adrenal extramedullary hematopoiesis associated with β-thalassemia major [0.03%]
重型β-地中海贫血相关的肾上腺髓外造血
Bijan Keikhaei,Ahmad Soltani Shirazi,Mahboob Mohammad Pour
Bijan Keikhaei
The presence of apparently normal hematopoietic tissue outside of bone marrow cavity is defined as extramedullary hematopoiesis (EMH). EMH is a rare complication in thalassemia major (TM) and adrenal gland as well. This report describes a c...
Case Reports
Hematology reports. 2012 May 10;4(2):e7. DOI:10.4081/hr.2012.e7 2012