Solamargine inhibited the progression of non-small cell lung cancer in vitro by activating T cells [0.03%]
索马辛通过激活T细胞抑制体外非小细胞肺癌的进展
Changchun Zhang,Yichen Sun,Wei Jiang et al.
Changchun Zhang et al.
Lung cancer is the leading cause of cancer-related death globally and the most common cancer type. Solamargine is an extract from the traditional Chinese medicine, Long Kui, which exhibits antitumor effects in a number of cancer types, incl...
circRNA-79530 regulates Twist-mediated mitochondrial damage via s ponging miR-214 affecting hypoxia/reoxygenation-induced injury in H9c2 cardiomyocytes [0.03%]
circRNA-79530通过海绵吸附miR-214调节Twist介导的线粒体损伤以影响H9c2心肌细胞中的缺氧/复氧诱导损伤
Ziyang Yu,Wenbo Xu,Yirong Teng et al.
Ziyang Yu et al.
Cardiomyocyte injury related to hypoxia/reoxygenation (H/R) is pivotal in myocardial infarction. The circular RNA circRNA-79530 (circ79530) may play a regulatory role in this process, though its exact function has yet to be elucidated. This...
Expression of bone morphogenetic protein signaling pathway players in the jejunum and colon of adult rats [0.03%]
成年大鼠空肠和结肠骨形态发生蛋白信号通路各成员的表达式研究
Emma Cogo,Edwin Fouché,Charline Buisson et al.
Emma Cogo et al.
The bone morphogenetic protein (BMP) pathway, which plays a crucial role in the control of intestinal epithelial cell homeostasis, has been studied in mice and humans, leading to an understanding of its involvement in several intestinal pat...
Aloe-emodin ameliorates chronic kidney disease fibrosis by inhibiting PI3K-mediated signaling pathway [0.03%]
大黄素通过抑制PI3 K信号通路改善慢性肾病纤维化
Ming Chen,Wenhui Zhu,Yao Chen et al.
Ming Chen et al.
Chronic kidney disease (CKD) impacts a vast number of individuals worldwide, culminating in renal fibrosis. Renal fibrosis serves as the main reason for end-stage renal failure. However, the current targeted treatment methods for renal fibr...
Beatrice Camia,Andrea Casasco,Manuela Monti
Beatrice Camia
The statement "Plastics define the way we live today" summarizes the findings of the Plastic Europe 2020 final document (https://plasticseurope.org/knowledge-hub/plastics-the-facts-2020/). Sadly, this also means that the plastic waste gener...
Histological and histochemical characterization of the musk gland in forest musk deer (Moschus berezovskii): a preliminary study [0.03%]
林麝鹿香腺的组织学和组织化学特征的初步研究
Qianyi Wang,Chunyu Han,Dong Zhang et al.
Qianyi Wang et al.
Musk is a biologically valuable secretion from the musk gland of male musk deer, with significant economic and medicinal importance. Due to severe decline and depletion of wild musk deer population, captive breeding of musk deer has become ...
NR4A3 suppresses bladder cancer progression by modulating autophagy via the PI3K/AKT/mTOR pathway [0.03%]
NR4A3通过PI3K/AKT/mTOR信号通路调节自噬从而抑制膀胱癌进展
Li Fan,Feng Xu,Shouyong Liu et al.
Li Fan et al.
Bladder cancer (BC) is a prevalent and aggressive malignancy with high recurrence. Autophagy plays a dual role in cancer, acting as a tumor suppressor early on and promoting survival in later stages. NR4A3, a nuclear receptor with tumor-sup...
Targeting EphA2 suppresses the proliferation, migration and invasion of endometriosis via the AMPK signaling pathway [0.03%]
靶向EphA2通过AMPK信号通路抑制子宫内膜增殖、迁移和侵袭
Chaoyi Yang,Shujun Wang,Mengru Li et al.
Chaoyi Yang et al.
Endometriosis is a benign disease with similar characteristics to tumors. Recent studies have found that the erythropoietin-producing hepatoma receptor A2 (EphA2) has the dual effect of promoting tumor and inhibiting tumor. The objective of...
Tanshinone IIA attenuates hepatic stellate cell activation, oxidative stress, and liver fibrosis by inhibiting YAP signaling [0.03%]
丹参酮 ⅡA通过抑制YAP信号通路减弱肝星状细胞活化、氧化应激及肝纤维化的作用
Dan Wang,Qingquan Tan,Qing Zheng et al.
Dan Wang et al.
Tanshinone IIA is derived from Salvia miltiorrhiza and has multiple therapeutic targets and functions. The exact therapeutic effects on liver fibrosis as well as the underlying hepatoprotective mechanisms are still lacking. A liver fibrosis...
Carlo Pellicciari
Carlo Pellicciari
Especially in the latest years, histochemical investigations have progressively been oriented toward the visualization and quantitative assessment of single molecules, thanks to the availability of stains, reactions and procedures allowing ...