Detection of autoantibodies to DSF70/LEDGFp75 in Mexican Hispanics using multiple complementary assay platforms [0.03%]
采用多种互补分析平台检测墨西哥裔美国人DSF70 / LEDGFp75自身抗体
Mónica Vázquez-Del Mercado,Eduardo Gómez-Bañuelos,Rosa Elena Navarro-Hernández et al.
Mónica Vázquez-Del Mercado et al.
Purpose: Antinuclear autoantibodies (ANA) targeting the dense fine speckled antigen DFS70, also known as lens epithelium-derived growth factor p75 (LEDGF/p75), are attracting attention due to their low frequency in system...
Development and evaluation of a standardized ELISA for the determination of autoantibodies against cN-1A (Mup44, NT5C1A) in sporadic inclusion body myositis [0.03%]
用于测定散发性包涵体肌炎中针对cN-1A（Mup44，NT5C1A）自身抗体的标准化ELISA的建立与评估
Sabine L Kramp,Dmitry Karayev,Guo Shen et al.
Sabine L Kramp et al.
Purpose: Sporadic inclusion body myositis (sIBM) is an autoimmune degenerative disease of the muscle, with inflammatory infiltrates and inclusion vacuoles. Its pathogenesis is not fully understood and the diagnosis is ham...
Anti-rods/rings autoantibody seropositivity does not affect response to telaprevir treatment for chronic hepatitis C infection [0.03%]
抗棒状/环状抗体阳性不影响特拉普_revir治疗慢性丙型肝炎的疗效
S John Calise,Nicola Bizzaro,Thuy Nguyen et al.
S John Calise et al.
Purpose: Autoantibodies to intracellular 'rods and rings' structures (anti-rods/rings or anti-RR) are strongly associated with hepatitis C (HCV) patients treated with interferon-α/ribavirin (IFN/RBV) and are linked with ...
Intraepithelial lymphocytes subsets in different forms of celiac disease [0.03%]
不同形式的乳糜泻中上皮内淋巴细胞亚群的区别
M Sánchez-Castañon,B G Castro,M Toca et al.
M Sánchez-Castañon et al.
Aim: The enumeration of intraepithelial lymphocytes subsets (total, γδ, and CD3(-) IELs) by flow cytometry (FCM), named as IEL lymphogram, constitutes a useful tool for celiac disease (CD) diagnosis. The aim of this stu...
Lazaros I Sakkas,Dimitrios P Bogdanos
Lazaros I Sakkas
Exogenous and endogenous environmental exposures and particularly infections may participate in the breakage of tolerance and the induction of autoimmunity in rheumatic diseases. Response to infections apparently occurs years before clinica...
Deciphering the role of DNA methylation in multiple sclerosis: emerging issues [0.03%]
解读DNA甲基化在多发性硬化症中的作用：新兴问题
Maria Sokratous,Efthimios Dardiotis,Zisis Tsouris et al.
Maria Sokratous et al.
Multiple sclerosis (MS) is an autoimmune inflammatory and neurodegenerative disease of the central nervous system that involves several not yet fully elucidated pathophysiologic mechanisms. There is increasing evidence that epigenetic modif...
Giulia Di Dalmazi,Jason Hirshberg,Daniel Lyle et al.
Giulia Di Dalmazi et al.
Reactive oxygen species (ROS) have been extensively studied in the induction of inflammation and tissue damage, especially as it relates to aging. In more recent years, ROS have been implicated in the pathogenesis of autoimmune diseases. He...
Measurement of anti-DFS70 antibodies in patients with ANA-associated autoimmune rheumatic diseases suspicion is cost-effective [0.03%]
怀疑患有ANA相关自身免疫性风湿病患者的抗DFS70抗体检测具有成本效益
Simón Gundín,Juan Irure-Ventura,Esther Asensio et al.
Simón Gundín et al.
The presence of antinuclear antibodies (ANA) is associated with a wide range of ANA-associated autoimmune rheumatic diseases (AARD). The most commonly method used for the detection of ANA is indirect immunofluorescence (IIF) on HEp-2 cells....
The ANA-reflex test as a model for improving clinical appropriateness in autoimmune diagnostics [0.03%]
ANA试验作为提高自身免疫性疾病诊断恰当性的模型研究
Elio Tonutti,Nicola Bizzaro,Gabriella Morozzi et al.
Elio Tonutti et al.
Reflex tests are widely used in clinical laboratories, for example, to diagnose thyroid disorders or in the follow-up of prostate cancer. Reflex tests for antinuclear antibodies (ANA) have recently gained attention as a way to improve appro...
Recognition of the dense fine speckled (DFS) pattern remains challenging: results from an international internet-based survey [0.03%]
密集细点状（DFS）染色模式的识别仍然具有挑战性：基于国际互联网调查的结果
Chelsea Bentow,Marvin J Fritzler,Eckart Mummert et al.
Chelsea Bentow et al.
Purpose: The dense fine speckled (DFS) pattern as detected by indirect immunofluorescence (IIF) on HEp-2 cells has been associated with several inflammatory diseases but is most commonly observed in individuals that do no...