A comprehensive analysis of antigen-specific autoimmune liver disease related autoantibodies in patients with multiple sclerosis [0.03%]
多发性硬化症患者自身免疫性肝病相关自身抗体的全面分析
Zisis Tsouris,Christos Liaskos,Efthymios Dardiotis et al.
Zisis Tsouris et al.
Introduction: Abnormal liver function tests are frequently seen in patients with multiple sclerosis (MS) and their origin at times is attributed to the possible co-occurrence or the de novo induction of autoimmune liver d...
Association of CD58 polymorphism and multiple sclerosis in Malaysia: a pilot study [0.03%]
CD58基因多态性与马来西亚多发性硬化症的关联：一项初步研究
Yee Ming Ching,Shanthi Viswanathan,Nurhanani Mohamed Nor et al.
Yee Ming Ching et al.
Background: Multiple sclerosis is an immune mediated disease targeting the central nervous system. Association of non-human leukocyte antigen gene, CD58, with multiple sclerosis has been reported in several populations bu...
HERV-K and HERV-W transcriptional activity in myalgic encephalomyelitis/chronic fatigue syndrome [0.03%]
肌痛性脑脊髓炎/慢性疲劳综合征中的HERV-K和HERV-W转录活性
Lucas S Rodrigues,Luiz H da Silva Nali,Cibele O D Leal et al.
Lucas S Rodrigues et al.
Background: Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/MS) is an incapacitating chronic disease that dramatically compromise the life quality. The CFS/ME pathogenesis is multifactorial, and it is believed tha...
Preclinical studies on the toxicology, pharmacokinetics and safety of K1-70TM a human monoclonal autoantibody to the TSH receptor with TSH antagonist activity [0.03%]
K1-70TM的毒理学、药代动力学和安全性以及一种具有促甲状腺激素(TSH)拮抗活性的人类单克隆自身抗体的临床前研究
Jadwiga Furmaniak,Jane Sanders,Jill Clark et al.
Jadwiga Furmaniak et al.
Background: The human monoclonal autoantibody K1-70™ binds to the TSH receptor (TSHR) with high affinity and blocks TSHR cyclic AMP stimulation by TSH and thyroid stimulating autoantibodies. ...
Evolving liver inflammation in biochemically normal individuals with anti-mitochondria antibodies [0.03%]
Biochemically正常但抗线粒体抗体阳性个体中肝脏炎症的演变规律
Danielle Cristiane Baldo,Alessandra Dellavance,Maria Lucia Gomes Ferraz et al.
Danielle Cristiane Baldo et al.
Background: Anti-mitochondria autoantibodies (AMA) occur in > 95% primary biliary cholangitis (PBC) patients. Biochemically normal AMA-positive (BN/AMA+) individuals, occasionally noticed by indirect immunofluorescence (I...
Antiphospholipid syndrome: a case report with an unusual wide spectrum of clinical manifestations [0.03%]
抗磷脂综合征一例罕见而独特的临床表现病例报告
Carmela Mazzoccoli,Domenico Comitangelo,Alessia D&#x;Introno et al.
Carmela Mazzoccoli et al.
Background: Antiphospholipid syndrome (APS) is an autoimmune disease characterized by the occurrence of venous and/or arterial thrombosis, and the detection of circulating antiphospholipid antibodies. The classification c...
Look granulomatosis with polyangiitis (GPA) straight in the face: missed opportunities leading to a delayed diagnosis [0.03%]
直面肉芽肿性多血管炎(GPA)：导致误诊的潜在风险因素分析
N Rolle,M Muruganandam,I Jan et al.
N Rolle et al.
Granulomatosis with polyangiitis (GPA) is a systemic vasculitis with a potential to involve any organ system. It remains an important cause of kidney related morbidity and mortality. Early diagnosis can be difficult and requires high index ...
Brain atrophy in multiple sclerosis: mechanisms, clinical relevance and treatment options [0.03%]
多发性硬化脑萎缩：机制、临床意义和治疗选择
Athina Andravizou,Efthimios Dardiotis,Artemios Artemiadis et al.
Athina Andravizou et al.
Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system characterized by focal or diffuse inflammation, demyelination, axonal loss and neurodegeneration. Brain atrophy can be seen in the earliest stages of MS, pr...
The clinical significance of atypical indirect immunofluorescence patterns on primate cerebellum in paraneoplastic antibody screening [0.03%]
以灵长类小脑为底物的免疫荧光模式在自身抗体检测中的意义
Joris Godelaine,Xavier Bossuyt,Koen Poesen
Joris Godelaine
Purpose: Screening for paraneoplastic antibodies is often performed by means of indirect immunofluorescence on primate cerebellar slices. However, atypical immunofluorescence patterns, i.e. patterns that are not specifica...
A new M23-based ELISA assay for anti-aquaporin 4 autoantibodies: diagnostic accuracy and clinical correlation [0.03%]
基于M23的新抗水通道蛋白4自身抗体ELISA检测方法：诊断准确性及其临床相关性研究
Marilina Tampoia,Letizia Abbracciavento,Giuseppina Barberio et al.
Marilina Tampoia et al.
Purpose: Although many assays have been developed to detect anti-aquaporin-4 (AQP4) antibodies, most of these assays require sophisticated techniques and are thus only available at specialized laboratories. The aim of thi...