Curcumin Lowers the Accelerated Speed of Epileptogenesis by Traumatic Brain Injury [0.03%]
姜黄素降低创伤性脑损伤诱发癫痫的速度
Hanieh Jahi,Mansoureh Eslami,Mohammad Sayyah et al.
Hanieh Jahi et al.
Background: Traumatic brain injury or TBI can underlie epilepsy. Prevention of PTE has been of great interest to scientists. Given the antiepileptic, antioxidant and anti-inflammatory activities of curcumin, we examined w...
Biocompatibility and Osseointegration of the Biomimetically Coated and Water-Soluble Eggshell Membrane Protein Cross-Linked Ti Alloy Screws [0.03%]
生物仿生涂层与水溶性蛋壳膜蛋白交联的Ti合金螺钉的生物相容性和骨整合性研究
Mehmet Bahadır İlik,Ercan Durmuş,İlhami Çelik
Mehmet Bahadır İlik
Background: The surface properties of dental and orthopedic implants are directly related to their osseointegration rate. Coating and/or modifying the implant surface might reduce the time of healing. In this study, we ai...
Polyethylene Glycol -Mediated Exosome Isolation: A Method for Exosomal RNA Analysis [0.03%]
聚乙二醇介导的外泌体分离：一种用于外泌体RNA分析的方法
Abdulwahab Teflischi Gharavi,Azadeh Niknejad,Saeed Irian et al.
Abdulwahab Teflischi Gharavi et al.
Background: : Exosomal RNAs (ExoRNAs) offer valuable insights into their cellular origin. ExoRNA studies were faced with challenges in obtaining sufficient amounts of high-quality RNA. Herein, we aimed to compare three tr...
In vitro Effect of EBV Infection on HERV-K18 env Expression in the Presence and Absence of Vitamin D in Multiple Sclerosis Patients [0.03%]
维生素D存在与否的EB病毒在多发性硬化症病人身上对HERV-K18 env表达的影响的试管研究
Tayebeh Latifi,Majid Teymoori-Rad,Ahmad Nejati et al.
Tayebeh Latifi et al.
Background: HERV-K env is associated with several neurological disorders, including MS. Clinical studies have demonstrated a plausible interaction between HERV-K env and other MS risk factors. The present study aimed to i...
Curcumin Modulates NOX Gene Expression and ROS Production via P-Smad3C in TGF-β-Activated Hepatic Stellate Cells [0.03%]
姜黄素通过TGF-β激活的肝星状细胞中的P-Smad3C调节NOX基因表达和ROS生成
Shahla Asadizade,Mahdi Hatami,Samaneh Salehipour Bavarsad et al.
Shahla Asadizade et al.
Background: Liver fibrosis, associated with hepatic stellate cells (HSCs), occurs when a healthy liver sustains damage, thereby impairing its function. NADPH oxidases (NOXs), specifically isoforms 1, 2, and 4, play a role...
Methylation Status of miR-34a and miR-126 in Non-Small Cell Lung Cancer (NSCLC) Tumor Tissues [0.03%]
非小细胞肺癌(NSCLC)肿瘤组织中miR-34a和miR-126的甲基化状态
Nazanin Mehrzad,Mohammad Saber Zamani,Amirabbas Rahimi et al.
Nazanin Mehrzad et al.
Background: MiR-34a and miR-126 mainly act as tumor suppressors and are often downregulated in various cancers, including non-small cell lung cancer (NSCLC). We aimed to determine the methylation status of miR-34a and miR...
Melittin as an Activator of the Autophagy and Unfolded Protein Response Pathways in Colorectal HCT116 Cell Line [0.03%]
蜂毒肽作为结肠直肠HCT116细胞系自噬和未折叠蛋白反应途径的激活剂
Mozhdeh Zamani,Farzaneh Bozorg-Ghalati,Pooneh Mokarram
Mozhdeh Zamani
Background: The potential anticancer effect of melittin has motivated scientists to find its exact molecular mechanism of action. There are few data on the effect of melittin on the UPR and autophagy as two critical pathw...
Erfaneh Jafari,Niloufar Soleymani,Masoud Hamidi et al.
Erfaneh Jafari et al.
Celiac disease (CD) is a complex disorder influenced by genetic and environmental factors. When people with a genetic predisposition to CD consume gluten, an inflammatory response is triggered in the small intestine, and this reaction can b...
Simvastatin-Loaded Nanoniosome Protects H9c2 Cells from Oxygen-Glucose Deprivation/ Reperfusion Injury by Downregulating Inflammation [0.03%]
载西立伐他汀纳米尼斯omes通过下调炎症保护H9c2细胞免受氧葡萄糖剥夺/再灌注损伤
Maryam Naseroleslami,Mahdieh Mehrab Mohseni
Maryam Naseroleslami
Background: Simvastatin (SIM) has anti-inflammatory and antioxidant properties against cardiac ischemia/reperfusion injury (I/RI). However, it suffers from low bioavailability and a short half-life. Nanoniosomes are novel...
Evaluation of t-DARPP Expression Alteration in Association with DDR1 Expression in Non-Small Cell Lung Cancer [0.03%]
t-DARPP表达改变与非小细胞肺癌中DDR1表达关联性的评估
Zahra Damavandi,Pardis Riahi,Tayebeh Majidizadeh et al.
Zahra Damavandi et al.
Background: Discoidin domain receptor 1 (DDR1) signaling plays a critical role in various cellular functions. Increased DDR1 expression has been shown in different human cancers. t-DARPP is a truncated isoform of DARPP-32...