Clonal Diversity and Genetic Landscape of mecC-Positive S. aureus in Human Samples from Iran: First Report of CC/ST423/t742 [0.03%]
伊朗人类样本中携带mecC的金黄色葡萄球菌的克隆多样性和遗传景观：首次报道携带CC/ST423/t742的菌株
Mehdi Goudarzi,Sima Sadat Seyedjavadi,Mozhgan Raigani et al.
Mehdi Goudarzi et al.
Background: The emergence of mecC-carrying Staphylococcus aureus strains is a serious concern in public health. Our study investigated the clonal diversity, genetic characteristics, antimicrobial resistance, virulence det...
Therapeutic Effects of Vernonia amygdalina on Oxidative Stress and Histopathological Damage in Pancreatic Toxicity Induced by 1,2-dimethylhydrazine in Wistar Rats [0.03%]
Vernonia amygdalina对1,2-二甲基肼诱导的Wistar大鼠胰毒性氧应激和组织病理损伤的治疗作用
Augustine O Okpiabhele,D Abu Osahon,E Akpovona Ambrose
Augustine O Okpiabhele
Background: 1,2-Dimethylhydrazine (DMH) induces pancreatic oxidative stress via reactive oxygen species overproduction and antioxidant depletion. Given the rich phytochemical and antioxidant properties of Vernonia amygdal...
Global Perspectives on Rabies Prevention and Control: A Decade of World Rabies Day Themes and Progress toward Elimination (2016–2025) [0.03%]
全球消除狂犬病行动十年(2016-2025):世界防治狂犬病日的主题及进展
Ashkan Alamdary,Mehdi Ajorloo,Alireza Gholami
Ashkan Alamdary
Rabies is a fatal zoonotic disease, responsible for approximately 59,000 human deaths annually; the majority occur in developing regions of Asia and Africa. This review explores worldwide efforts to prevent and control rabies during 2016-20...
Antidepressant Effects of L-Arginine and Its Role in Brain Energy Metabolism [0.03%]
L-arginine抗抑郁作用及其在脑能量代谢中的角色
T Mantashashvili,L Nakaidze,M Shengelia et al.
T Mantashashvili et al.
Background: Mitochondrial dysfunction and impaired cellular energy metabolism are increasingly recognized as key contributing factors in depression. This study evaluated the amino acid L-arginine as a potential agent for ...
Molecular Characterization of Multi-Drug Resistant Histamine-Producing Gram-Negative Bacteria Isolated from Fermented Prosopis africana Seeds (okpee) in Nigeria [0.03%]
尼日利亚发酵Prosopis africana种子（Okpee）中产生的多种耐药组胺产生革兰氏阴性菌的分子特征化研究
Adonu Cyril,Urama Sunday,Abugu Felix et al.
Adonu Cyril et al.
Background: Fermented Prosopis africana seeds (okpee) are naturally protein-rich but exude odors that attract houseflies. These flies can carry contaminants, including pathogens and histamine-producing bacteria. Bacterial...
Whole-Exome Sequencing Identified a Novel Mutation in an Iranian Patient with Epidermolysis Bullosa [0.03%]
全外显子组测序在一位伊朗交界性肢端雀斑样黑色素瘤患者中发现新的突变
Reza Mirfakhraie,Solmaz Hassani Fard Katiraei,Mina Mirnezami et al.
Reza Mirfakhraie et al.
Background: Epidermolysis bullosa (EB) is a rare, genetically heterogeneous disorder characterized by skin fragility. EB is categorized into four types: simplex, junctional, dystrophic, and Kindler syndromes. The conditio...
Resveratrol in Combination Therapy: Mechanisms and Limitations of Resveratrol in Cancer, Regeneration, and Chronic Disease [0.03%]
白藜芦醇联合疗法：癌症、再生和慢性疾病中白藜芦醇的作用机制与局限性
Effat Noori,Ramazan Rezaei,Samira Valiyari et al.
Effat Noori et al.
Resveratrol (RSV), a nonflavonoid polyphenol phytoalexin, has considerable therapeutic potential for managing chronic and acute diseases due to its anti-inflammatory, anti-cancer, antimicrobial, and antioxidant properties. It can help prote...
Antiviral Potential of Lipopeptide Biosurfactant Isolated from Acinetobacter junii B6 [0.03%]
来源于不动杆菌的脂肽生物表面活性剂抗病毒潜力研究
Amir Mohammad Bagheri,Hamid Forootanfar,Gholamreza Dehghannoudeh et al.
Amir Mohammad Bagheri et al.
Background: Influenza A virus (IAV) is a global health concern, increasing the exploration of alternative therapeutics. Biosurfactants (BSs) are biodegradable, non-toxic biomolecules with favorable biological activities. ...
Effect of HIF-1α and LDHA Blockade on Gene Expression of Tumor Immune Evasion in Myeloid Leukemia Cell Lines [0.03%]
缺氧诱导因子-1α和乳酸脱氢酶A抑制对髓系白血病细胞系肿瘤免疫逃逸基因表达的影响
Tamana Eskandari,Mehrshad Shams,Ali Khanari et al.
Tamana Eskandari et al.
Background: Tumor cells utilize metabolic reprogramming to obtain the energy required for rapid proliferation. In this study, we blocked two key factors, hypoxia-inducible factor 1-alpha (HIF-1α) and lactate dehydrogenas...
Design and Mode of Action of a New Synthetic Antibacterial Peptide against Pseudomonas aeruginosa [0.03%]
一种新的合成抗菌肽的设计、作用方式及其针对绿脓杆菌的效果研究
Armineh Azadian,Hamideh Mahmoodzadeh Hosseini,Seyed Ali Mirhosseini et al.
Armineh Azadian et al.
Background: Research into antimicrobial peptides (AMPs) and other novel antimicrobial strategies continues to be a focus of the scientific community to address the growing challenges posed by antibiotic resistance. The ai...