Whole-Exome Sequencing Identified a Novel Mutation in an Iranian Patient with Epidermolysis Bullosa [0.03%]
全外显子组测序在一位伊朗交界性肢端雀斑样黑色素瘤患者中发现新的突变
Reza Mirfakhraie,Solmaz Hassani Fard Katiraei,Mina Mirnezami et al.
Reza Mirfakhraie et al.
Background: Epidermolysis bullosa (EB) is a rare, genetically heterogeneous disorder characterized by skin fragility. EB is categorized into four types: simplex, junctional, dystrophic, and Kindler syndromes. The conditio...
Resveratrol in Combination Therapy: Mechanisms and Limitations of Resveratrol in Cancer, Regeneration, and Chronic Disease [0.03%]
白藜芦醇联合疗法：癌症、再生和慢性疾病中白藜芦醇的作用机制与局限性
Effat Noori,Ramazan Rezaei,Samira Valiyari et al.
Effat Noori et al.
Resveratrol (RSV), a nonflavonoid polyphenol phytoalexin, has considerable therapeutic potential for managing chronic and acute diseases due to its anti-inflammatory, anti-cancer, antimicrobial, and antioxidant properties. It can help prote...
Antiviral Potential of Lipopeptide Biosurfactant Isolated from Acinetobacter junii B6 [0.03%]
来源于不动杆菌的脂肽生物表面活性剂抗病毒潜力研究
Amir Mohammad Bagheri,Hamid Forootanfar,Gholamreza Dehghannoudeh et al.
Amir Mohammad Bagheri et al.
Background: Influenza A virus (IAV) is a global health concern, increasing the exploration of alternative therapeutics. Biosurfactants (BSs) are biodegradable, non-toxic biomolecules with favorable biological activities. ...
Effect of HIF-1α and LDHA Blockade on Gene Expression of Tumor Immune Evasion in Myeloid Leukemia Cell Lines [0.03%]
缺氧诱导因子-1α和乳酸脱氢酶A抑制对髓系白血病细胞系肿瘤免疫逃逸基因表达的影响
Tamana Eskandari,Mehrshad Shams,Ali Khanari et al.
Tamana Eskandari et al.
Background: Tumor cells utilize metabolic reprogramming to obtain the energy required for rapid proliferation. In this study, we blocked two key factors, hypoxia-inducible factor 1-alpha (HIF-1α) and lactate dehydrogenas...
Design and Mode of Action of a New Synthetic Antibacterial Peptide against Pseudomonas aeruginosa [0.03%]
一种新的合成抗菌肽的设计、作用方式及其针对绿脓杆菌的效果研究
Armineh Azadian,Hamideh Mahmoodzadeh Hosseini,Seyed Ali Mirhosseini et al.
Armineh Azadian et al.
Background: Research into antimicrobial peptides (AMPs) and other novel antimicrobial strategies continues to be a focus of the scientific community to address the growing challenges posed by antibiotic resistance. The ai...
Exercise-Induced Lactate Is Associated with the Modulation of Mitophagy and Ferroptosis and Reduced Amyloid-Beta and Tau in Type 2 Diabetes [0.03%]
运动诱导的乳酸与线粒体自噬和铁死亡调节及Ⅱ型糖尿病小鼠脑内淀粉样蛋白-β和tau减少有关
Pouria Khosravi,Fereshteh Shahidi,Arezoo Eskandari et al.
Pouria Khosravi et al.
Background: Type 2 diabetes (T2D) is associated with increased oxidative stress, impaired mitophagy, enhanced ferroptosis, and the accumulation of amyloid beta (Aβ) and hyperphosphorylated tau in the hippocampus. Exercis...
Expression of Epithelial-Mesenchymal Transition-Related Genes in Primary Brain Tumors [0.03%]
原发性脑肿瘤中上皮间质转化相关基因的表达
Shiva Bayat,Negar Mousavi,Fatemeh Vand-Rajabpour et al.
Shiva Bayat et al.
Background: Gliomas are the most common malignant primary brain tumors in adults. Meningiomas, on the other hand, are benign primary brain tumors treated by surgical resection. Epithelial-to-mesenchymal transition (EMT), ...
Quercetin and 5-Fluorouracil Synergistically Suppress ZEB1 and Restore Epithelial Integrity in Triple-Negative Breast Cancer [0.03%]
槲皮素和氟尿嘧啶协同抑制三阴性乳腺癌中的ZEB1并恢复上皮完整性
Leila Nejat,Mahdi Hatami,Maryam Adelipour et al.
Leila Nejat et al.
Background: Triple-negative breast cancer (TNBC) remains a therapeutic challenge due to its metastatic features and resistance to conventional therapies. This study investigated the synergistic potential of quercetin (QC)...
Hamidreza Saber,Zahra Mousavipour
Hamidreza Saber
Adenoviral vectors (AdVs) represent one of the most extensively researched platforms in the realm of gene therapy, providing advantages such as high transduction efficiency, large transgene capacity, and broad tropism. This review provides ...
Bacteroides thetaiotaomicron and Human Health: A Bibliometric Analysis of Global Research Trends [0.03%]
拟杆菌和人类健康：全球研究趋势的计量分析
Farzaneh Hasanian-Langroudi,Mehdi Hedayati,Farzad Esmaeili et al.
Farzaneh Hasanian-Langroudi et al.
Bacteroides thetaiotaomicron is a highly abundant Gram-negative anaerobic bacterium that plays a crucial role in maintaining intestinal homeostasis and modulating intestinal diseases. A bibliometric study was conducted to examine global pub...