Extracellular cholesterol oxidase from Rhodococcus sp.: isolation and molecular characterization [0.03%]
来自Rhodococcus菌的胞外胆固醇氧化酶：分离和分子特征分析
Hamed Lashkarian,Jamshid Raheb,Kiana Shahzamani et al.
Hamed Lashkarian et al.
Background: Cholesterol oxidase (CHO) has various clinical and industrial applications. Recently, microbial CHO have received a great attention for their wide usage in medicine. Here, taxonomic characterizations of isolat...
Role of estrogen receptor- α in an experimental model of bronchial asthma [0.03%]
雌激素受体-α在支气管哮喘实验模型中的作用研究
Saloni P Shah,Priyanshee V Gohil,Gaurang B Shah
Saloni P Shah
Background: Use of hormone replacement therapy (HRT) may increase the risk of adult-onset asthma in women. Various in vitro studies have reported that estradiol stimulates human mast cell lines causing release of allergic...
Chronic oral pelargonidin alleviates streptozotocin-induced diabetic neuropathic hyperalgesia in rat: involvement of oxidative stress [0.03%]
苯甲酰素缓解链尿佐菌素诱导的大鼠糖尿病神经性疼痛：氧化应激的参与作用
Mohammadali Mirshekar,Mehrdad Roghani,Mohsen Khalili et al.
Mohammadali Mirshekar et al.
Background: Diabetes mellitus in some clinical cases is accompanied with hyperalgesia. In this study, we evaluated the possible beneficial effect of chronic pelargonidin (PG) treatment on hyperalgesia in streptozotocin (S...
Cytotoxicity of subtoxic AgNP in human hepatoma cell line (HepG2) after long-term exposure [0.03%]
长期暴露条件下银离子纳米颗粒对人肝癌细胞（HepG2）的细胞毒性作用研究
Azin Nowrouzi,Khadijeh Meghrazi,Taghi Golmohammadi et al.
Azin Nowrouzi et al.
We aimed at evaluating the toxicity effects of low (subtoxic) concentrations of silver nanoparticles nanoparticles (AgNP, 5-10 nm) in human hepatoblastoma (HepG2) cell line after and during a period of about one month. ...
The effect of aspartate-lysine-isoleucine and aspartate-arginine-tyrosine mutations on the expression and activity of vasopressin V2 receptor gene [0.03%]
天冬氨酸-赖氨酰异亮氨酸和天冬氨酸-精氨酰酪氨酸变异对血管加压素V2受体基因表达及活性的影响
Hossein Najafzadeh,Leila Safaeian,Hamid Mirmohammad Sadeghi et al.
Hossein Najafzadeh et al.
Background: Vasopressin type 2 receptor (V2R) plays an important role in the water reabsorption in the kidney collecting ducts. V2R is a G protein coupled receptor (GPCR) and the triplet of amino acids aspartate-arginine-...
Differential gene-expression of metallothionein 1M and 1G in response to zinc in sertoli TM4 cells [0.03%]
TM4支持细胞中金属硫蛋白1M和1G对锌的表达反应差异性分析研究
Fatemeh Kheradmand,Issa Nourmohammadi,Mohammad Hossein Modarressi et al.
Fatemeh Kheradmand et al.
Background: Zinc (Zn) as an important trace element is essential for testicular development and spermatogenesis. Molecular mechanism of Zn action in the reproductive system may be related to metal binding low-molecular we...
Bcr-abl silencing by specific small-interference RNA expression vector as a potential treatment for chronic myeloid leukemia [0.03%]
用小干挠RNA表达载体特异沉默bcr-abl作为治疗慢性粒细胞白血病的潜在方法
Ali Zaree Mahmodabady,Hamid Reza Javadi,Mehdi Kamali et al.
Ali Zaree Mahmodabady et al.
Background: RNA interference (RNAi) is the mechanism of gene silencing-mediated messenger RNA degradation by small interference RNA (siRNA), which becomes a powerful tool for in vivo research, especially in the areas of c...